All Outputs (128)

Applications of digital technology in Covid-19 pandemic planning and response (2020)
Journal Article
Mamas. (2020). Applications of digital technology in Covid-19 pandemic planning and response. Lancet, https://doi.org/10.1016/S2589-7500%2820%2930142-4

With high transmissibility and no effective vaccine or therapy, COVID-19 is now a global pandemic. Government-coordinated efforts across the globe have focused on containment and mitigation, with varying degrees of success. Countries that have mainta... Read More about Applications of digital technology in Covid-19 pandemic planning and response.

Impact of coronary lesion complexity in percutaneous coronary intervention: 1-year outcomes from the large, multicenter e-ULTIMASTER registry (2020)
Journal Article
Mamas. (2020). Impact of coronary lesion complexity in percutaneous coronary intervention: 1-year outcomes from the large, multicenter e-ULTIMASTER registry. https://doi.org/10.4244/EIJ-D-20-00361

Aims: The present study sought to examine the prevalence, clinical characteristics and 1-year outcomes of patients undergoing percutaneous coronary intervention (PCI) to complex lesions (multivessel PCI, =3 stents, =3 lesions, bifurcation with =2 ste... Read More about Impact of coronary lesion complexity in percutaneous coronary intervention: 1-year outcomes from the large, multicenter e-ULTIMASTER registry.

A systematic review of the studies that evaluate the performance of the DAPT score. (2020)
Journal Article
Mamas. (2020). A systematic review of the studies that evaluate the performance of the DAPT score. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13591

BACKGROUND: The Dual Antiplatelet Therapy (DAPT) score was derived to determine which patients may benefit from prolonged DAPT therapy after 12 months based on the balance between ischemic and bleeding events. Several studies have attempted to valida... Read More about A systematic review of the studies that evaluate the performance of the DAPT score..

Outcomes of Percutaneous Coronary Intervention in Patients with Crohn’s Disease and Ulcerative Colitis (from a nationwide cohort) (2020)
Journal Article
Nolan, & Mamas. (2020). Outcomes of Percutaneous Coronary Intervention in Patients with Crohn’s Disease and Ulcerative Colitis (from a nationwide cohort). American Journal of Cardiology, 30-36. https://doi.org/10.1016/j.amjcard.2020.06.013

Patients with inflammatory bowel disease (IBD) are at an increased risk of ischemic heart disease. However, there is limited evidence on how their outcomes after percutaneous coronary intervention (PCI) compare to those without IBD. All PCI-related h... Read More about Outcomes of Percutaneous Coronary Intervention in Patients with Crohn’s Disease and Ulcerative Colitis (from a nationwide cohort).

Impact of Charlson Comorbidity Index Score on Management and Outcomes after Acute Coronary Syndrome (2020)
Journal Article
Mamas. (2020). Impact of Charlson Comorbidity Index Score on Management and Outcomes after Acute Coronary Syndrome. American Journal of Cardiology, https://doi.org/10.1016/j.amjcard.2020.06.022

Patients presenting with acute coronary syndrome (ACS) are frequently comorbid. However, there is limited data on how comorbidity burden impacts their receipt of invasive management and subsequent outcomes. We analyzed all patients with a discharge d... Read More about Impact of Charlson Comorbidity Index Score on Management and Outcomes after Acute Coronary Syndrome.

Impact of Charlson Comorbidity Index Score on Management and Outcomes after Acute Coronary Syndrome (2020)
Journal Article
Mamas. (2020). Impact of Charlson Comorbidity Index Score on Management and Outcomes after Acute Coronary Syndrome. American Journal of Cardiology, 15-23. https://doi.org/10.1016/j.amjcard.2020.06.022

Patients presenting with acute coronary syndrome (ACS) are frequently comorbid. However, there is limited data on how comorbidity burden impacts their receipt of invasive management and subsequent outcomes. We analyzed all patients with a discharge d... Read More about Impact of Charlson Comorbidity Index Score on Management and Outcomes after Acute Coronary Syndrome.

Proximal Left Anterior Descending Artery Treatment Using a Bioresorbable Polymer Coating Sirolimus-Eluting Stent: Real-World Outcomes From the Multicenter Prospective e-Ultimaster Registry (vol 8, e013786, 2019) (2020)
Journal Article
Mamas. (2020). Proximal Left Anterior Descending Artery Treatment Using a Bioresorbable Polymer Coating Sirolimus-Eluting Stent: Real-World Outcomes From the Multicenter Prospective e-Ultimaster Registry (vol 8, e013786, 2019). Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, https://doi.org/10.1161/JAHA.119.014539

Correction.

FRI0610-HPR Β-ADRENORECEPTOR BLOCKING DRUGS ASSOCIATE WITH LOWER RISK OF KNEE OSTEOARTHRITIS AND KNEE PAIN CONSULTATIONS IN PRIMARY CARE: A PROPENSITY SCORE MATCHED COHORT STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK. (2020)
Presentation / Conference
Nakafero, G., Grainge, M., Valdes, A., Townsend, N., Mallen, C., Zhang, W., …Abhishek, A. (2020, June). FRI0610-HPR Β-ADRENORECEPTOR BLOCKING DRUGS ASSOCIATE WITH LOWER RISK OF KNEE OSTEOARTHRITIS AND KNEE PAIN CONSULTATIONS IN PRIMARY CARE: A PROPENSITY SCORE MATCHED COHORT STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK

Background: The pharmacologic management of OA is centred around optimising pain control but first-line analgesics only have modest efficacy1. Findings from several studies suggest that β-adrenoreceptor blocking drugs (β-blockers) have anti-nocicepti... Read More about FRI0610-HPR Β-ADRENORECEPTOR BLOCKING DRUGS ASSOCIATE WITH LOWER RISK OF KNEE OSTEOARTHRITIS AND KNEE PAIN CONSULTATIONS IN PRIMARY CARE: A PROPENSITY SCORE MATCHED COHORT STUDY USING THE CLINICAL PRACTICE RESEARCH DATALINK..

Association between Hospital Cardiac Catheter Laboratory Status, use of an Invasive Strategy and Outcomes after NSTEMI (2020)
Journal Article
Mamas, Nolan, & Rashid. (2020). Association between Hospital Cardiac Catheter Laboratory Status, use of an Invasive Strategy and Outcomes after NSTEMI. Canadian Journal of Cardiology, 868-877. https://doi.org/10.1016/j.cjca.2019.10.010

Background
While previous studies report increased use of invasive coronary strategy in patients admitted to hospitals with onsite cardiac catheter laboratory (CCL) facilities, the utility of invasive coronary strategy according to types of CCL faci... Read More about Association between Hospital Cardiac Catheter Laboratory Status, use of an Invasive Strategy and Outcomes after NSTEMI.

Are Higher Operator Volumes for Unprotected Left Main Stem Percutaneous Coronary Intervention Associated With Improved Patient Outcomes?: A Survival Analysis of 6724 Procedures From the British Cardiovascular Intervention Society National Database. (2020)
Journal Article
Mamas. (2020). Are Higher Operator Volumes for Unprotected Left Main Stem Percutaneous Coronary Intervention Associated With Improved Patient Outcomes?: A Survival Analysis of 6724 Procedures From the British Cardiovascular Intervention Society National Database. Circulation: Cardiovascular Interventions, e008782 - ?. https://doi.org/10.1161/CIRCINTERVENTIONS.119.008782

BACKGROUND: The relationship between operator volume and survival after unprotected left main stem percutaneous coronary intervention (uLMS-PCI) is poorly defined. METHODS: Data from the British Cardiovascular Intervention Society national PCI databa... Read More about Are Higher Operator Volumes for Unprotected Left Main Stem Percutaneous Coronary Intervention Associated With Improved Patient Outcomes?: A Survival Analysis of 6724 Procedures From the British Cardiovascular Intervention Society National Database..

Temporal Trends in Comorbidity Burden and Impact on Prognosis in Patients With Acute Coronary Syndrome Using the Elixhauser Comorbidity Index Score. (2020)
Journal Article
Mamas. (2020). Temporal Trends in Comorbidity Burden and Impact on Prognosis in Patients With Acute Coronary Syndrome Using the Elixhauser Comorbidity Index Score. American Journal of Cardiology, 1603-1611. https://doi.org/10.1016/j.amjcard.2020.02.044

Despite current evidence, little is known about the impact of comorbidity burden on invasive management strategies and clinical outcomes in the context of acute coronary syndrome (ACS). All ACS hospitalizations between 2004 and 2014 from the National... Read More about Temporal Trends in Comorbidity Burden and Impact on Prognosis in Patients With Acute Coronary Syndrome Using the Elixhauser Comorbidity Index Score..

Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction. (2020)
Journal Article
Mallen, C., Belcher, J., Mamas, M., Clarson, L., Welsh, V., & Bajpai, R. (2020). Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction. Heart, 916-922. https://doi.org/10.1136/heartjnl-2019-315511

OBJECTIVES: Despite many shared risk factors and pathophysiological pathways, the risk of ischaemic heart disease (IHD) and myocardial infarction (MI) in interstitial lung disease (ILD) remains poorly understood. This lack of data could be preventing... Read More about Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction..

Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction (2020)
Journal Article
Elise Clarson, L., Bajpai, R., Whittle, R., Belcher, J., Abdul Sultan, A., Shing Kwok, C., …Mallen, C. D. (2020). Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction. Heart, Article 12. https://doi.org/10.1136/heartjnl-2019-315511

Objectives Despite many shared risk factors and pathophysiological pathways, the risk of ischaemic heart disease (IHD) and myocardial infarction (MI) in interstitial lung disease (ILD) remains poorly understood. This lack of data could be preventing... Read More about Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction.

Understanding the Analytics of Twitter in Cardiovascular Medicine. (2020)
Journal Article
Mamas. (2020). Understanding the Analytics of Twitter in Cardiovascular Medicine. https://doi.org/10.1016/j.jaccas.2020.03.008

Role of Coronary Computed Tomography Angiography in Percutaneous Coronary Intervention of Chronic Total Occlusions (2020)
Journal Article
Velagapudi, P., Abbott, J. D., Mamas, M., Blankstein, R., Chatzizisis, Y. S., Brilakis, E. S., & Jaffer, F. A. (2020). Role of Coronary Computed Tomography Angiography in Percutaneous Coronary Intervention of Chronic Total Occlusions. Current Cardiovascular Imaging Reports, 13(7), Article 20. https://doi.org/10.1007/s12410-020-09541-3

Despite significant advances in procedural techniques for revascularization of chronic total occlusions (CTO), comprehensive procedural planning and accurate prediction of procedural success remain the Achilles’ heels of CTO percutaneous coronary int... Read More about Role of Coronary Computed Tomography Angiography in Percutaneous Coronary Intervention of Chronic Total Occlusions.

Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study. (2020)
Journal Article
Mamas, Chew-Graham, & Mallen. (2020). Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study. BMJ Open Diabetes Research and Care, https://doi.org/10.1136/bmjdrc-2019-000962

OBJECTIVE: Clinically applicable diabetes severity measures are lacking, with no previous studies comparing their predictive value with glycated hemoglobin (HbA1c). We developed and validated a type 2 diabetes severity score (the DIabetes Severity SC... Read More about Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study..

Evaluation of the DAPT score in patients who undergo percutaneous coronary intervention in England and Wales. (2020)
Journal Article
Mamas. (2020). Evaluation of the DAPT score in patients who undergo percutaneous coronary intervention in England and Wales. Cardiovascular Revascularization Medicine, 1509-1514. https://doi.org/10.1016/j.carrev.2020.05.003

This study aims to evaluate the temporal changes in DAPT score and determine whether there is an association between DAPT score and mortality. We analyzed all patients who underwent PCI in England and Wales 2007-2014. Statistical analyses were perfor... Read More about Evaluation of the DAPT score in patients who undergo percutaneous coronary intervention in England and Wales..

Prevalence and in-hospital outcomes of patients with malignancies undergoing de novo cardiac electronic device implantation in the United States (2020)
Journal Article
Mamas. (2020). Prevalence and in-hospital outcomes of patients with malignancies undergoing de novo cardiac electronic device implantation in the United States. EP-Europace, 1083-1096. https://doi.org/10.1093/europace/euaa087

Aims: To study the outcomes of cancer patients undergoing cardiac implantable electronic device (CIED) implantation.

Methods: De novo CIED implantations (2004 to 2015; n=2,670,590) from the National Inpatient Sample were analysed for characterist... Read More about Prevalence and in-hospital outcomes of patients with malignancies undergoing de novo cardiac electronic device implantation in the United States.

Institutional use of National Clinical Audits by healthcare providers (2020)
Journal Article
Mamas. (2020). Institutional use of National Clinical Audits by healthcare providers. Journal of Evaluation in Clinical Practice, https://doi.org/10.1111/jep.13403

Abstract Rationale, aims, and objectives Healthcare systems worldwide devote significant resources towards collecting data to support care quality assurance and improvement. In the United Kingdom, National Clinical Audits are intended to contribute t... Read More about Institutional use of National Clinical Audits by healthcare providers.

Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis. (2020)
Journal Article
Mamas. (2020). Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis. Annals of Internal Medicine, 474 - 483

BACKGROUND: The safety and effectiveness of dual therapy (direct oral anticoagulant [DOAC] plus P2Y12 inhibitor) versus triple therapy (vitamin K antagonist plus aspirin and P2Y12 inhibitor) in patients with nonvalvular atrial fibrillation (AF) after... Read More about Dual Versus Triple Therapy for Atrial Fibrillation After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis..