Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative

Chan, Christopher; Combes, Gill; Davies, Simon; Finkelstein, Fred; Firanek, Catherine; Gomez, Rafael; Jager, Kitty J.; Jha George, Vivek; Johnson, David W.; Lambie, Mark; Madero, Magdalena; Masakane, Ikuto; McDonald, Stephen; Misra, Madhukar; Mitra, Sandip; Moraes, Thyago; Nadeau-Fredette, Annie-Claire; Mukhopadhyay, Purna; Perl, Jeff; Pisoni, Ronald; Robinson, Bruce; Ryu, Dong-Ryeol; Saran, Rajiv; Sloand, James; Sukul, Nidhi; Tong, Allison; Szeto, Cheuk-Chun; Van Biesen, Wim

doi:10.3747/pdi.2017.00242

All Outputs (6)

How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies (2019)
Journal Article
Barrowman, M. A., Peek, N., Lambie, M., Martin, G. P., & Sperrin, M. (2019). How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies. BMC medical research methodology, 19, Article 166. https://doi.org/10.1186/s12874-019-0808-7

Background
Analysis of competing risks is commonly achieved through a cause specific or a subdistribution framework using Cox or Fine & Gray models, respectively. The estimation of treatment effects in observational data is prone to unmeasured confo... Read More about How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies.

Attitudes towards Peritoneal Dialysis among Peritoneal Dialysis and Hemodialysis Medical Directors: Are we preaching to the right choir? (2019)
Journal Article
Shen, J. I., Schreiber, M. J., Zhao, J., Robinson, B. M., Pisoni, R. L., Mehrotra, R., …Perl, J. (2019). Attitudes towards Peritoneal Dialysis among Peritoneal Dialysis and Hemodialysis Medical Directors: Are we preaching to the right choir?. Clinical Journal of the American Society of Nephrology, 14(7), 1067-1070. https://doi.org/10.2215/CJN.01320119

Research letter.

Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018) (2019)
Journal Article
Davies, & Lambie. (2019). Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018). Clinical Journal of the American Society of Nephrology, 909 - 909. https://doi.org/10.2215/CJN.02830319

Background and objectives: The inflammation-driven increase in peritoneal solute transport rate that occurs during long-term peritoneal dialysis is associated with higher mortality, hospitalization, and encapsulating peritoneal sclerosis. Because bio... Read More about Biocompatible solutions and long-term changes in peritoneal solute transport (vol 13, pg 1526, 2018).

Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death (2019)
Journal Article
Lambie, M., Teece, L., Johnson, D. W., Petrie, M., Mactier, R., Solis-Trapala, I., …Davies, S. J. (2019). Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death. Nephrology Dialysis Transplantation, 1585-1591. https://doi.org/10.1093/ndt/gfz034

Background
Risk of Encapsulating Peritoneal Sclerosis (EPS) is strongly associated with the duration of peritoneal dialysis (PD), such that patients who have been on PD for some time may consider elective transfer to haemodialysis to mitigate risk o... Read More about Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death.

Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients (2019)
Journal Article
Yu, Z., Lambie, M., Chess, J., Williams, A., Do, J., Topley, N., & Davies, S. J. (2019). Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients. Frontiers in Physiology, 10, 105 -105. https://doi.org/10.3389/fphys.2019.00105

It is not clear whether the association of increased peritoneal protein clearance with worse survival on PD is a consequence of either local or systemic inflammation or indicative of generalized endothelial dysfunction associated with comorbidity. To... Read More about Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients.

Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative (2019)
Journal Article
Chan, C., Combes, G., Davies, S., Finkelstein, F., Firanek, C., Gomez, R., …Van Biesen, W. (2019). Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 39(1), 4 -12. https://doi.org/10.3747/pdi.2017.00242

Patients with end-stage kidney disease (ESKD) have different options to replace the function of their failing kidneys. The "integrated care" model considers treatment pathways rather than individual renal replacement therapy (RRT) techniques. In such... Read More about Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative.