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Alternative models to support weight loss in chronic musculoskeletal conditions: effectiveness of a physiotherapist-delivered intensive diet programme for knee osteoarthritis, the POWER randomised controlled trial (2024)
Journal Article
Allison, K., Jones, S., Hinman, R. S., Pardo, J., Li, P., DeSilva, A., …Bennell, K. L. (2024). Alternative models to support weight loss in chronic musculoskeletal conditions: effectiveness of a physiotherapist-delivered intensive diet programme for knee osteoarthritis, the POWER randomised controlled trial. British Journal of Sports Medicine, 58(10), 538-547. https://doi.org/10.1136/bjsports-2023-107793

Objectives: To determine if physiotherapists can deliver a clinically effective very low energy diet (VLED) supplementary to exercise in people with knee osteoarthritis (OA) and overweight or obesity. Methods: 88 participants with knee OA and bod... Read More about Alternative models to support weight loss in chronic musculoskeletal conditions: effectiveness of a physiotherapist-delivered intensive diet programme for knee osteoarthritis, the POWER randomised controlled trial.

Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals (2024)
Journal Article
Simkins, J., Holden, M. A., Babatunde, O., White, S., Nicholls, E., Long, A., …O’Brien, N. (2024). Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals. Musculoskeletal Care, 22(1), Article e1873. https://doi.org/10.1002/msc.1873

Introduction Osteoarthritis is the commonest form of chronic joint pain, which patients often self-manage before seeking healthcare advice. Patients frequently seek advice from community pharmacies, and a recent policy has recommended integrating co... Read More about Exploring the potential extended role of community pharmacy in the management of osteoarthritis: A multi‐methods study with pharmacy staff and other healthcare professionals.

Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA) (2024)
Journal Article
Babatunde, O. O., Cottrell, E., White, S., Chudyk, A., Healey, E. L., Edwards, J., …Holden, M. A. (in press). Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA). BMC Musculoskeletal Disorders, 25(1), Article 54. https://doi.org/10.1186/s12891-023-07105-2

Background Osteoarthritis is a common, painful and disabling long-term condition. Delivery of high-quality guideline-informed osteoarthritis care that successfully promotes and maintains supported self-management is imperative. However, osteoarthrit... Read More about Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA).

The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis (2023)
Journal Article
Kigozi, J., Oppong, R., Paskins, Z., Bromley, K., Lewis, M., Hughes, G., …Roddy, E. (2023). The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis. Rheumatology, https://doi.org/10.1093/rheumatology/kead659

Objectives. Evidence for the comparative cost-effectiveness of intra-articular corticosteroid injection in people with hip osteoarthritis (OA) remains unclear. This study investigated the cost-effectiveness of best current treatment (BCT) comprising... Read More about The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis.

A new measure of exercise adherence: the ATEMPT (Adherence To Exercise for Musculoskeletal Pain Tool) (2023)
Journal Article
Bailey, D. L., Bishop, A., McCray, G., Foster, N. E., & Holden, M. A. (2023). A new measure of exercise adherence: the ATEMPT (Adherence To Exercise for Musculoskeletal Pain Tool). British Journal of Sports Medicine, 58(2), bjsports-2022-106347. https://doi.org/10.1136/bjsports-2022-106347

Objectives: This study aimed to (1) develop a new measure of adherence to exercise for musculoskeletal (MSK) pain (Adherence To Exercise for Musculoskeletal Pain Tool: ATEMPT) based on previously conceptualised domains of exercise adherence, (2) repo... Read More about A new measure of exercise adherence: the ATEMPT (Adherence To Exercise for Musculoskeletal Pain Tool).

Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study (2023)
Journal Article
Hawarden, A., Holden, M. A., Paskins, Z., Roddy, E., Mallen, C. D., Liddle, J., …Jinks, C. (2023). Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study. Musculoskeletal Care, https://doi.org/10.1002/msc.1830

Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic, or local anaesthetic alone, to advice and education among people with... Read More about Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study.

Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank (2023)
Journal Article
Runhaar, J., A Holden, M., Hattle, M., Quicke, J., Healey, E. L., van der Windt, D., …Menek, M. Y. (2023). Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank. RMD Open, 9(3), Article e003220. https://doi.org/10.1136/rmdopen-2023-003220

Objectives: To evaluate mediating factors for the effect of therapeutic exercise on pain and physical function in people with knee/hip osteoarthritis (OA). Methods: For Subgrouping and TargetEd Exercise pRogrammes for knee and hip OsteoArthritis (... Read More about Mechanisms of action of therapeutic exercise for knee and hip OA remain a black box phenomenon: an individual patient data mediation study with the OA Trial Bank.

Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment? (2023)
Journal Article
Nicolson, P. J. A., & Holden, M. A. (2023). Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment?. Current Treatment Options in Rheumatology, 9(3), 120-131. https://doi.org/10.1007/s40674-023-00208-w

Purpose of review: Patient-centred care for people with osteoarthritis requires shared decision making. Understanding and considering patients’ preferences for osteoarthritis treatments is central to this. In this narrative review, we present an over... Read More about Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment?.

Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis (2023)
Journal Article
Holden, M. A., Hattle, M., Runhaar, J., Riley, R. D., Healey, E. L., Quicke, J., …Exercise Collaborative, O. T. B. (2023). Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis. The Lancet Rheumatology, 5(7), e386-e400. https://doi.org/10.1016/S2665-9913%2823%2900122-4

Background Many international clinical guidelines recommend therapeutic exercise as a core treatment for knee and hip osteoarthritis. We aimed to identify individual patient-level moderators of the effect of therapeutic exercise for reducing pain an... Read More about Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis.

Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). (2023)
Journal Article
Foster, N. E., Nicholls, E., Holden, M. A., Healey, E. L., Hay, E. M., & trial team, T. B. (2023). Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial). Archives of Rehabilitation Research and Clinical Translation, 5(2), Article 100266. https://doi.org/10.1016/j.arrct.2023.100266

To investigate whether knee osteoarthritis (OA) related pain and function can be improved by offering enhanced physical therapist-led exercise interventions. Three-arm prospectively designed pragmatic randomized controlled trial. General practices an... Read More about Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial)..

Tailored exercise management (TEMPO) versus usual care for people aged 80 years or older with hip/knee osteoarthritis: study protocol for a feasibility randomised controlled trial (2023)
Journal Article
Nicolson, P. J. A., Holden, M. A., Marian, I. R., Williamson, E., Dutton, S. J., Garrett, A., …Lamb, S. E. (in press). Tailored exercise management (TEMPO) versus usual care for people aged 80 years or older with hip/knee osteoarthritis: study protocol for a feasibility randomised controlled trial. Pilot and Feasibility Studies, 9(1), Article 56. https://doi.org/10.1186/s40814-023-01275-5

Background: Exercise is recommended for all people with osteoarthritis. However, these recommendations are based on randomised clinical trials including people with an average age between 60 and 70 years, and these findings cannot reliably be genera... Read More about Tailored exercise management (TEMPO) versus usual care for people aged 80 years or older with hip/knee osteoarthritis: study protocol for a feasibility randomised controlled trial.

Evaluating Osteoarthritis Management Programs: outcome domain recommendations from the OARSI Joint Effort Initiative. (2023)
Journal Article
Allen, K., Huffman, K., Cleveland, R., van der Esch, M., Abbott, J., Abbott, A., …Hinman, R. (2023). Evaluating Osteoarthritis Management Programs: outcome domain recommendations from the OARSI Joint Effort Initiative. Osteoarthritis and Cartilage, 31(7), 954-965. https://doi.org/10.1016/j.joca.2023.02.078

Objective To develop sets of core and optional recommended domains for describing and evaluating Osteoarthritis Management Programs (OAMPs), with a focus on hip and knee Osteoarthritis (OA). Design We conducted a 3-round modified Delphi survey i... Read More about Evaluating Osteoarthritis Management Programs: outcome domain recommendations from the OARSI Joint Effort Initiative..

What should a toolkit to aid the delivery of therapeutic exercise for hip and knee osteoarthritis look like? Qualitative analysis of an international survey of 318 researchers, clinicians, and consumers by the OARSI Rehabilitation Discussion Group (2023)
Journal Article
Holden, M. A., Lawford, B. J., Master, H., Larsen, J. B., Bartholdy, C., Corrigan, P., …White, D. K. (2023). What should a toolkit to aid the delivery of therapeutic exercise for hip and knee osteoarthritis look like? Qualitative analysis of an international survey of 318 researchers, clinicians, and consumers by the OARSI Rehabilitation Discussion Group. Musculoskeletal Care, 21(2), 545-555. https://doi.org/10.1002/msc.1732

BACKGROUND: We aimed to identify important components of, and practical resources relevant for inclusion in, a toolkit to aid exercise delivery for people with hip/knee osteoarthritis. METHOD: An online international multi-disciplinary survey was con... Read More about What should a toolkit to aid the delivery of therapeutic exercise for hip and knee osteoarthritis look like? Qualitative analysis of an international survey of 318 researchers, clinicians, and consumers by the OARSI Rehabilitation Discussion Group.

Conceptualising adherence to exercise for musculoskeletal pain: A concept mapping study (2022)
Journal Article
Bailey, D., Bishop, A., Foster, N. E., & Holden, M. A. (2023). Conceptualising adherence to exercise for musculoskeletal pain: A concept mapping study. Physiotherapy Research International, 28(2), https://doi.org/10.1002/pri.1989

AbstractBackgroundThe concept of adherence to exercise for musculoskeletal (MSK) pain is poorly defined and inadequately measured. This study aimed to, (1) conceptualise adherence to exercise therapy for MSK pain, and (2) identify statements most rep... Read More about Conceptualising adherence to exercise for musculoskeletal pain: A concept mapping study.

Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group (2022)
Journal Article
Holden, M., Metcalf, B., Lawford, B., Hinman, R., Boyd, M., Button, K., …Bennell, K. (2023). Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group. Osteoarthritis and Cartilage, 31(3), 386-396. https://doi.org/10.1016/j.joca.2022.10.009

Objective To develop evidence-informed recommendations to support the delivery of best practice therapeutic exercise for people with knee and/or hip osteoarthritis (OA). Design A multi-stage, evidence-informed, international multi-disciplinary c... Read More about Recommendations for the delivery of therapeutic exercise for people with knee and/or hip osteoarthritis. An international consensus study from the OARSI Rehabilitation Discussion Group.

Osteoarthritis year in review 2022: rehabilitation (2022)
Journal Article
Holden, M., Nicolson, P., Thomas, M., Corp, N., Hinman, R., & Bennell, K. (2023). Osteoarthritis year in review 2022: rehabilitation. Osteoarthritis and Cartilage, 31(2), 177-186. https://doi.org/10.1016/j.joca.2022.10.004

This year in review presents key highlights from research relating to osteoarthritis (OA) rehabilitation published from the 1st April 2021 to the 18th March 2022. To identify studies for inclusion in the review, an electronic database search was carr... Read More about Osteoarthritis year in review 2022: rehabilitation.

Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial. (2022)
Journal Article
Holden. (2022). Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial. BMC Musculoskeletal Disorders, 733 - ?. https://doi.org/10.1186/s12891-022-05685-z

BACKGROUND: Obesity is associated with knee osteoarthritis (OA). Weight loss, alongside exercise, is a recommended treatment for individuals with knee OA and overweight/obesity. However, many patients cannot access weight loss specialists such as die... Read More about Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial..

POS1106 MEDIATORS OF THE EFFECT OF THERAPEUTIC EXERCISE ON PAIN AND FUNCTION IN PATIENTS WITH KNEE AND HIP OSTEOARTHRITIS; AN INDIVIDUAL PATIENT DATA MEDIATION STUDY FROM THE OA TRIAL BANK. (2022)
Journal Article
Runhaar, J., Holden, M., Hattle, M., Quicke, J., Riley, R., Healey, E., …Foster, N. (2022). POS1106 MEDIATORS OF THE EFFECT OF THERAPEUTIC EXERCISE ON PAIN AND FUNCTION IN PATIENTS WITH KNEE AND HIP OSTEOARTHRITIS; AN INDIVIDUAL PATIENT DATA MEDIATION STUDY FROM THE OA TRIAL BANK. Annals of the Rheumatic Diseases, 81(Suppl 1), 881.2-882. https://doi.org/10.1136/annrheumdis-2022-eular.530