A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.

Bowerman, Mélissa; Murray, Lyndsay M.; Beauvais, Ariane; Pinheiro, Bruno; Kothary, Rashmi

doi:10.1016/j.nmd.2011.09.007

All Outputs (46)

Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology (2014)
Journal Article
Bowerman, M., Michalski, J., Beauvais, A., Murray, L. M., DeRepentigny, Y., & Kothary, R. (2014). Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology. Human molecular genetics, 23(13), 3432-3444. https://doi.org/10.1093/hmg/ddu052

Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis (2013)
Journal Article
Bowerman, M., Vincent, T., Scamps, F., Perrin, F. E., Camu, W., & Raoul, C. Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis. Frontiers in Cellular Neuroscience, 7, https://doi.org/10.3389/fncel.2013.00214

The Neuroinflammation in the Physiopathology of Amyotrophic Lateral Sclerosis (2013)
Book Chapter
Bowerman, M., Vincent, T., Scamps, F., Camu, W., & Raoul, C. The Neuroinflammation in the Physiopathology of Amyotrophic Lateral Sclerosis. In Current Advances in Amyotrophic Lateral Sclerosis. InTech. https://doi.org/10.5772/56489

Glucose metabolism and pancreatic defects in spinal muscular atrophy. (2012)
Journal Article
Bowerman, M., Swoboda, K. J., Michalski, J., Wang, G., Reeks, C., Beauvais, A., …Kothary, R. (2012). Glucose metabolism and pancreatic defects in spinal muscular atrophy. Annals of Neurology, https://doi.org/10.1002/ana.23582

Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy. (2012)
Journal Article
Bowerman, M., Murray, L. M., Boyer, J. G., Anderson, C. L., & Kothary, R. (2012). Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy. BMC Medicine, https://doi.org/10.1186/1741-7015-10-24

A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology. (2012)
Journal Article
Bowerman, M., Murray, L. M., Beauvais, A., Pinheiro, B., & Kothary, R. (2012). A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology. Neuromuscular Disorders, https://doi.org/10.1016/j.nmd.2011.09.007