All Outputs (30)

An investigation into the synthesis of azido-functionalised coumarins for application in 1,3-dipolar "click" cycloaddition reactions (2016)
Journal Article
Watkinson. (2016). An investigation into the synthesis of azido-functionalised coumarins for application in 1,3-dipolar "click" cycloaddition reactions. Dyes and Pigments, 36 - 40. https://doi.org/10.1016/j.dyepig.2016.06.028

A range of reported methods have been assessed for the synthesis of two coumarin fluorophores containing azides, 1a and 2, for subsequent “click” modification. In the case of 1a reported methods were successfully applied, but the resulting azide prov... Read More about An investigation into the synthesis of azido-functionalised coumarins for application in 1,3-dipolar "click" cycloaddition reactions.

The effect of gold nanoparticles on the impedance of microcapsules visualized by scanning photo-induced impedance microscopy (2016)
Journal Article
Watkinson. (2016). The effect of gold nanoparticles on the impedance of microcapsules visualized by scanning photo-induced impedance microscopy. Electrochimica Acta, 39 - 46. https://doi.org/10.1016/j.electacta.2016.05.017

Polyelectrolyte microcapsules have attracted great interest in drug delivery applications, and microcapsules modified with gold nanoparticles have been used in this way with triggered release when a laser can be used to remotely open shells through l... Read More about The effect of gold nanoparticles on the impedance of microcapsules visualized by scanning photo-induced impedance microscopy.

Incorporation of Cobalt-Cyclen Complexes into Templated Nanogels Results in Enhanced Activity (2015)
Journal Article
Jorge, A. R., Chernobryva, M., Rigby, S. E. J., Watkinson, M., & Resmini, M. (2016). Incorporation of Cobalt-Cyclen Complexes into Templated Nanogels Results in Enhanced Activity. Chemistry - A European Journal, 22(11), 3764-3774. https://doi.org/10.1002/chem.201503946

Recent advances in nanomaterials have identified nanogels as an excellent matrix for novel biomimetic catalysts using the molecular imprinting approach. Polymerisable Co-cyclen complexes with phosphonate and carbonate templates have been prepared, fu... Read More about Incorporation of Cobalt-Cyclen Complexes into Templated Nanogels Results in Enhanced Activity.

“Click” Patterning of Self-Assembled Monolayers on Hydrogen-Terminated Silicon Surfaces and Their Characterization Using Light-Addressable Potentiometric Sensors (2015)
Journal Article
Wang, J., Wu, F., Watkinson, M., Zhu, J., & Krause, S. (2015). “Click” Patterning of Self-Assembled Monolayers on Hydrogen-Terminated Silicon Surfaces and Their Characterization Using Light-Addressable Potentiometric Sensors. Langmuir, 31(35), 9646-9654. https://doi.org/10.1021/acs.langmuir.5b02069

Two potential strategies for chemically patterning alkyne-terminated self-assembled monolayers (SAMs) on oxide-free silicon or silicon-on-sapphire (SOS) substrates were investigated and compared. The patterned surfaces were validated using a light-ad... Read More about “Click” Patterning of Self-Assembled Monolayers on Hydrogen-Terminated Silicon Surfaces and Their Characterization Using Light-Addressable Potentiometric Sensors.

Disposable MMP-9 sensor based on the degradation of peptide cross-linked hydrogel films using electrochemical impedance spectroscopy (2015)
Journal Article
Biela, A., Watkinson, M., Meier, U. C., Baker, D., Giovannoni, G., Becer, C. R., & Krause, S. (2015). Disposable MMP-9 sensor based on the degradation of peptide cross-linked hydrogel films using electrochemical impedance spectroscopy. Biosensors and Bioelectronics, 68, 660-667. https://doi.org/10.1016/j.bios.2015.01.060

Matrix metalloproteinase-9 (MMP-9) plays an important role in both physiological and pathological processes. This enzyme is a peripheral biomarker of neuroinflammation in multiple sclerosis (MS), a chronic autoimmune disease of the central nervous sy... Read More about Disposable MMP-9 sensor based on the degradation of peptide cross-linked hydrogel films using electrochemical impedance spectroscopy.

High-sensitivity light-addressable potentiometric sensors using silicon on sapphire functionalized with self-assembled organic monolayers (2014)
Journal Article
Wang, J., Zhou, Y., Watkinson, M., Gautrot, J., & Krause, S. (2015). High-sensitivity light-addressable potentiometric sensors using silicon on sapphire functionalized with self-assembled organic monolayers. Sensors and Actuators B: Chemicall, 209, 230-236. https://doi.org/10.1016/j.snb.2014.11.071

The use of self-assembled organic monolayers as the insulator in light-addressable potentiometric sensors (LAPS) is shown for the first time. Silicon on sapphire (SOS) substrates were modified with 1-octadecene or undecylenic acid. Experiments with a... Read More about High-sensitivity light-addressable potentiometric sensors using silicon on sapphire functionalized with self-assembled organic monolayers.

Biologically targeted probes for Zn2+: a diversity oriented modular “click-SNAr-click” approach (2014)
Journal Article
Watkinson. (2014). Biologically targeted probes for Zn2+: a diversity oriented modular “click-SNAr-click” approach. Chemical Science, 3528-3535. https://doi.org/10.1039/C4SC01249F

We describe a one-pot strategy for the high yielding, operationally simple synthesis of fluorescent probes for Zn2+ that bear biological targeting groups and exemplify the utility of our method through the preparation of a small library of sensors. I... Read More about Biologically targeted probes for Zn2+: a diversity oriented modular “click-SNAr-click” approach.

Catalytic and mechanistic studies into the epoxidation of styrenes using manganese complexes of structurally similar polyamine ligands (2013)
Journal Article
Ilyashenko, G., De Faveri, G., Follier, T., Al-Safadi, R., Motevalli, M., & Watkinson, M. (in press). Catalytic and mechanistic studies into the epoxidation of styrenes using manganese complexes of structurally similar polyamine ligands. Organic and Biomolecular Chemistry, 12(7), 1124-1134. https://doi.org/10.1039/c3ob42274g

Two structurally similar polyamine ligands (7 and 8) have been prepared, which differ only by the presence of either a secondary or tertiary nitrogen donor within their N5 donor set. The ligands, in combination with iron and manganese salts, have bee... Read More about Catalytic and mechanistic studies into the epoxidation of styrenes using manganese complexes of structurally similar polyamine ligands.

A synthesis of a 1,1′-desymmetrised ferrocene backbone and its facile one-pot double-“click” functionalisation (2013)
Journal Article
Ilyashenko, G., Al-Safadi, R., Donnan, R., Dubrovka, R., Pancholi, J., Watkinson, M., & Whiting, A. (2013). A synthesis of a 1,1′-desymmetrised ferrocene backbone and its facile one-pot double-“click” functionalisation. RSC advances, 3(38), 17081. https://doi.org/10.1039/c3ra43054e

A one-pot, four-component, copper-catalysed double-“click” functionalisation of a novel 1,1′-desymmetrised ferrocene backbone is reported. Using an array of alkynes and azides, a library of ferrocene compounds was developed, demonstrating the scope o... Read More about A synthesis of a 1,1′-desymmetrised ferrocene backbone and its facile one-pot double-“click” functionalisation.

Initial rate kinetic studies show an unexpected influence of para-substituents on the catalytic behaviour of manganese complexes of TMTACN in the epoxidation of styrenes with H2O2 (2013)
Journal Article
Ilyashenko, G., De Faveri, G., Masoudi, S., Al-Safadi, R., & Watkinson, M. (2013). Initial rate kinetic studies show an unexpected influence of para-substituents on the catalytic behaviour of manganese complexes of TMTACN in the epoxidation of styrenes with H2O2. Organic and Biomolecular Chemistry, 11(12), 1942. https://doi.org/10.1039/c3ob27217f

Investigations into the efficacy of a range of enantiomerically pure BINOL additives in the epoxidation of styrene substrates with a number of manganese catalysts prepared from the ligand 1,4,7-trimethyl-1,4,7-triazacyclononane, TMTACN, using hydroge... Read More about Initial rate kinetic studies show an unexpected influence of para-substituents on the catalytic behaviour of manganese complexes of TMTACN in the epoxidation of styrenes with H2O2.