The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial.

Healey, E; Herron, D; Hider, S; Bucknall, M; Cooke, K; Finney, A; Goddin, D; Hennings, S; Jinks, C; Lewis, M; Machin, A; Mallen, C; Wathall, S; Chew-Graham, C

doi:10.1177/2235042X18792373

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. (2018)
Journal Article
Chesterton, L. S., Blagojevic-Bucknall, M., Burton, C., Dziedzic, K. S., Davenport, G., Jowett, S. M., …Roddy, E. (2018). The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial. The Lancet, 392(10156), 1423 - 1433. https://doi.org/10.1016/s0140-6736%2818%2931572-1

Background To our knowledge, the comparative effectiveness of commonly used conservative treatments for carpal tunnel syndrome has not been evaluated previously in primary care. We aimed to compare the clinical and cost-effectiveness of night splint... Read More about The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial..

The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study (2018)
Journal Article
Blagojevic‐Bucknall, M., Mallen, C., Muller, S., Hayward, R., West, S., Choi, H., & Roddy, E. (2019). The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study. Arthritis & Rheumatology, 71(1), 154-160. https://doi.org/10.1002/art.40662

Objective Obstructive sleep apnea (OSA) is associated with a range of serious comorbidities. This study investigates whether people with OSA are more likely to develop gout than those without OSA in both short and long term. Methods A matched ret... Read More about The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study.

Comorbidity clusters in people with gout: an observational cohort study with linked medical record review (2018)
Journal Article
Mallen, Roddy, Bucknall, & Hider. (2018). Comorbidity clusters in people with gout: an observational cohort study with linked medical record review. Rheumatology, 1358-1363. https://doi.org/10.1002/acr.23562

Objective. To investigate how comorbid conditions cluster in patients with gout in a UK primary care population. Methods. A cross-sectional study was performed using baseline data from a primary-care-based prospective observational cohort of peop... Read More about Comorbidity clusters in people with gout: an observational cohort study with linked medical record review.

Health-related quality of life in gout in primary care: baseline findings from a cohort study (2018)
Journal Article
Roddy, Mallen, Bucknall, Muller, & Hider. (2018). Health-related quality of life in gout in primary care: baseline findings from a cohort study. Seminars in Arthritis and Rheumatism, 61-69. https://doi.org/10.1016/j.semarthrit.2017.12.005

Objectives: To examine gout-related, comorbid, and sociodemographic characteristics associated with generic and disease-specific health-related quality of life (HRQOL) in gout. Methods: Adults with gout from 20 general practices were mailed a que... Read More about Health-related quality of life in gout in primary care: baseline findings from a cohort study.

Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Muller, Hider, Helliwell, & Paskins. (2018). Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study. Osteoporosis International, 1659-1664. https://doi.org/10.1007/s00198-018-4491-z

This study aimed to examine fracture risk in patients with late-onset psoriasis. A cohort study was conducted using primary care records from the Clinical Practice Research Datalink. Psoriasis patients had a 10% increased risk of fracture compared to... Read More about Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study.

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials (2018)
Report
Hay, E., Dziedzic, K., Foster, N., Peat, G., van der Windt, D., Bartlam, B., …Croft, P. (2018). Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials. NIHR. PGfAR as project number RP-PG-0407-10386. Secretary of State for Health and Social Care

Background Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based interventions can reduce OA pain and disability. Objectives Th... Read More about Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.

How common is depression in patients with polymyalgia rheumatica? (2018)
Journal Article
Mallen, Bucknall, Belcher, & Hider. (2018). How common is depression in patients with polymyalgia rheumatica?. Clinical Rheumatology, 1633 - 1638. https://doi.org/10.1007/s10067-017-3691-9

Depression is common in inflammatory disorders such as rheumatoid arthritis and systemic lupus erythematosus and negatively impacts on outcomes. Given the long-term nature of polymyalgia rheumatica (PMR) and its glucocorticoid treatment, these patien... Read More about How common is depression in patients with polymyalgia rheumatica?.

Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy (2018)
Journal Article
Paskins, Mallen, Bucknall, Hider, Muller, Helliwell, & Roddy. (2018). Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy. Canadian Medical Association Journal, E581 -E587. https://doi.org/10.1503/cmaj.170806

BACKGROUND: Previous studies that quantified the risk of fracture among patients with gout and assessed the potential effect of urate-lowering therapy have provided conflicting results. Our study aims to provide better estimates of risk by minimizing... Read More about Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy.

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Hider, Muller, Paskins, & Helliwell. (2018). Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. BMC Medicine, https://doi.org/10.1186/s12916-017-0987-1

Background Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.

The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. (2018)
Journal Article
Healey, E., Herron, D., Hider, S., Bucknall, M., Cooke, K., Finney, A., …Chew-Graham, C. (2018). The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. Journal of Comorbidity, 8(1), https://doi.org/10.1177/2235042X18792373

Background: Patients with inflammatory rheumatic conditions such as rheumatoid arthritis, polymyalgia rheumatica and ankylosing spondylitis are at increased risk of common comorbidities such as cardiovascular disease, osteoporosis and anxiety and dep... Read More about The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial..

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