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Health-related quality of life in gout in primary care: baseline findings from a cohort study (2018)
Journal Article
Roddy, Mallen, Bucknall, Muller, & Hider. (2018). Health-related quality of life in gout in primary care: baseline findings from a cohort study. Seminars in Arthritis and Rheumatism, 61-69. https://doi.org/10.1016/j.semarthrit.2017.12.005

Objectives: To examine gout-related, comorbid, and sociodemographic characteristics associated with generic and disease-specific health-related quality of life (HRQOL) in gout. Methods: Adults with gout from 20 general practices were mailed a que... Read More about Health-related quality of life in gout in primary care: baseline findings from a cohort study.

Comorbidity clusters in people with gout: an observational cohort study with linked medical record review (2018)
Journal Article
Mallen, Roddy, Bucknall, & Hider. (2018). Comorbidity clusters in people with gout: an observational cohort study with linked medical record review. Rheumatology, 1358-1363. https://doi.org/10.1002/acr.23562

Objective. To investigate how comorbid conditions cluster in patients with gout in a UK primary care population. Methods. A cross-sectional study was performed using baseline data from a primary-care-based prospective observational cohort of peop... Read More about Comorbidity clusters in people with gout: an observational cohort study with linked medical record review.

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials (2018)
Report
Hay, E., Dziedzic, K., Foster, N., Peat, G., van der Windt, D., Bartlam, B., …Croft, P. (2018). Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials. NIHR. PGfAR as project number RP-PG-0407-10386. Secretary of State for Health and Social Care

Background Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based interventions can reduce OA pain and disability. Objectives Th... Read More about Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.

Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Muller, Hider, Helliwell, & Paskins. (2018). Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study. Osteoporosis International, 1659-1664. https://doi.org/10.1007/s00198-018-4491-z

This study aimed to examine fracture risk in patients with late-onset psoriasis. A cohort study was conducted using primary care records from the Clinical Practice Research Datalink. Psoriasis patients had a 10% increased risk of fracture compared to... Read More about Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study.

How common is depression in patients with polymyalgia rheumatica? (2018)
Journal Article
Mallen, Bucknall, Belcher, & Hider. (2018). How common is depression in patients with polymyalgia rheumatica?. Clinical Rheumatology, 1633 - 1638. https://doi.org/10.1007/s10067-017-3691-9

Depression is common in inflammatory disorders such as rheumatoid arthritis and systemic lupus erythematosus and negatively impacts on outcomes. Given the long-term nature of polymyalgia rheumatica (PMR) and its glucocorticoid treatment, these patien... Read More about How common is depression in patients with polymyalgia rheumatica?.

Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy (2018)
Journal Article
Paskins, Mallen, Bucknall, Hider, Muller, Helliwell, & Roddy. (2018). Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy. Canadian Medical Association Journal, E581 -E587. https://doi.org/10.1503/cmaj.170806

BACKGROUND: Previous studies that quantified the risk of fracture among patients with gout and assessed the potential effect of urate-lowering therapy have provided conflicting results. Our study aims to provide better estimates of risk by minimizing... Read More about Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy.

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Hider, Muller, Paskins, & Helliwell. (2018). Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. BMC Medicine, https://doi.org/10.1186/s12916-017-0987-1

Background Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.

The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. (2018)
Journal Article
Healey, E., Herron, D., Hider, S., Bucknall, M., Cooke, K., Finney, A., …Chew-Graham, C. (2018). The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. Journal of Comorbidity, 8(1), https://doi.org/10.1177/2235042X18792373

Background: Patients with inflammatory rheumatic conditions such as rheumatoid arthritis, polymyalgia rheumatica and ankylosing spondylitis are at increased risk of common comorbidities such as cardiovascular disease, osteoporosis and anxiety and dep... Read More about The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial..

SAT0672 Risk of fragility fracture among patients with psoriasis: a population based matched cohort study from the united kingdom (2017)
Presentation / Conference
Paskins, Z., Whittle, R., Sultan, A. A., Muller, S., Helliwell, T., Blagojevic-Bucknall, M., …Mallen, C. (2017, June). SAT0672 Risk of fragility fracture among patients with psoriasis: a population based matched cohort study from the united kingdom. Poster presented at Annual European Congress of Rheumatology, 14–17 June, 2017

183. GOUT AS A CONSEQUENCE OF SLEEP APNOEA: A MATCHED COHORT STUDY (2017)
Journal Article
Blagojevic-Bucknall, M., Mallen, C., Muller, S., Hayward, R., West, S., Choi, H., & Roddy, E. (2017). 183. GOUT AS A CONSEQUENCE OF SLEEP APNOEA: A MATCHED COHORT STUDY. Rheumatology, 56(suppl_2), https://doi.org/10.1093/rheumatology/kex062.184

Background: Gout and obstructive sleep apnoea are both common problems in primary care and associated with considerable co-morbidity. Serum uric acid levels are frequently elevated in sleep apnoea patients and one previous cohort study found that peo... Read More about 183. GOUT AS A CONSEQUENCE OF SLEEP APNOEA: A MATCHED COHORT STUDY.

Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink (2017)
Journal Article
Roddy, E., Muller, S., Paskins, Z., Hider, S., Blagojevic-Bucknall, M., & Mallen, C. (2017). Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink. Medicine, https://doi.org/10.1097/MD.0000000000006177

Oral bisphosphonates are the most commonly used drugs to treat postmenopausal osteoporosis. Acute pseudogout is anecdotally reported to occur following bisphosphonate initiation but empirical data are lacking. We investigated whether treatment with o... Read More about Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink.

The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome (2016)
Journal Article
Chesterton, L. S., Dziedzic, K. S., Van Der Windt, D. A., Davenport, G., Myers, H. L., Rathod, T., …Hay, E. M. (2016). The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome. BMC Musculoskeletal Disorders, 415 - ?. https://doi.org/10.1186/s12891-016-1264-8

BACKGROUND: Patients diagnosed with idiopathic mild to moderate carpal tunnel syndrome (CTS) are usually managed in primary care and commonly treated with night splints and/or corticosteroid injection. The comparative effectiveness of these intervent... Read More about The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome.

Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care. (2016)
Journal Article
Wilkie, R., Blagojevic-Bucknall, M., Belcher, J., Chew-Graham, C., Lacey, R. J., & McBeth, J. (2016). Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care. Medicine, 95(31), Article e4111. https://doi.org/10.1097/MD.0000000000004111

In older adults, reduced social participation increases the risk of poor health-related quality of life, increased levels of inflammatory markers and cardiovascular disease, and increased mortality. Older adults frequently present to primary care, wh... Read More about Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care..

PATIENT PRIORITIES FOR PMR RESEARCH: A PRIMARY CARE SURVEY (2016)
Journal Article
Hider, S., Morton, C., Muller, S., Belcher, J., Gilbert, K., Bucknall, M., & Mallen, C. (2016). PATIENT PRIORITIES FOR PMR RESEARCH: A PRIMARY CARE SURVEY. Annals of the Rheumatic Diseases, 75, 169-169. https://doi.org/10.1136/annrheumdis-2016-eular.5915

Background Polymyalgia rheumatica (PMR) is a common inflammatory disorder of older (>50 years) adults, frequently managed in primary care. PMR remains under-researched despite the significant impact this condition has on patient's quality of life. Ex... Read More about PATIENT PRIORITIES FOR PMR RESEARCH: A PRIMARY CARE SURVEY.

Impairment-targeted exercises for older adults with knee pain: a proof-of-principle study (TargET-Knee-Pain). (2016)
Journal Article
Wood, L., Blagojevic-Bucknall, M., Stynes, S., D'Cruz, D., Mullis, R., Whittle, R., …Foster, N. (2016). Impairment-targeted exercises for older adults with knee pain: a proof-of-principle study (TargET-Knee-Pain). BMC Musculoskeletal Disorders, 47 - ?. https://doi.org/10.1186/s12891-016-0899-9

BACKGROUND: Therapeutic exercise is an effective intervention for knee pain and osteoarthritis (OA) and should be individualised. In a preliminary, proof-of-principle study we sought to develop a home exercise programme targeted at specific physical... Read More about Impairment-targeted exercises for older adults with knee pain: a proof-of-principle study (TargET-Knee-Pain)..

Foot problems in people with gout in primary care: baseline findings from a prospective cohort study (2015)
Journal Article
Bucknall, Roddy, Mallen, Hider, & Muller. (2015). Foot problems in people with gout in primary care: baseline findings from a prospective cohort study. Journal of Foot and Ankle Research, 31 - ?. https://doi.org/10.1186/s13047-015-0090-9

BACKGROUND: Foot problems are common in people with gout yet the prevalence of current foot problems in people with gout and the burden they present to healthcare systems is not known. This cross-sectional study aimed to determine the prevalence and... Read More about Foot problems in people with gout in primary care: baseline findings from a prospective cohort study.

Repeated primary care consultations for non-specific physical symptoms in children in UK: a cohort study (2014)
Journal Article
Bucknall, M., Mallen, C. D., & Dunn, K. M. (2014). Repeated primary care consultations for non-specific physical symptoms in children in UK: a cohort study. BMC Family Practice, 195 - ?. https://doi.org/10.1186/s12875-014-0195-4

BackgroundNon-specific physical symptoms (NSPS), such as headache and abdominal pain, are common reasons for children to consult primary care. NSPS represent a significant burden not only on society, but also on health care services, through frequent... Read More about Repeated primary care consultations for non-specific physical symptoms in children in UK: a cohort study.