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Inhibition of Human T-Cell Proliferation by mTOR antagonists requires Non-Coding RNA growth-arrest-specific transcript 5 (GAS5) (2010)
Journal Article
Mourtada-Maarabouni, M., Hasan, A. M., Farzaneh, F., & Williams, G. T. (2010). Inhibition of Human T-Cell Proliferation by mTOR antagonists requires Non-Coding RNA growth-arrest-specific transcript 5 (GAS5). Molecular Pharmacology, 78(1), 19 - 28. https://doi.org/10.1124/mol.110.064055

BACKGROUND: Eosinophils are characteristic participants in allergic inflammation. The intracellular signalling mechanisms involved in the migration of eosinophils to sites of allergic inflammation are poorly understood. Chemotactic responses of eosin... Read More about Inhibition of Human T-Cell Proliferation by mTOR antagonists requires Non-Coding RNA growth-arrest-specific transcript 5 (GAS5).

Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5) (2010)
Journal Article
Mourtada-Maarabouni, M., Hasan, A. M., Farzaneh, F., & Williams, G. T. (2010). Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5). Molecular Pharmacology, 78(1), 19-28. https://doi.org/10.1124/mol.110.064055

The central importance of the serine/threonine protein kinase mTOR (mammalian Target of Rapamycin) in the control of cell growth and proliferation is well established. However, our knowledge both of the upstream pathways controlling mTOR activity and... Read More about Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5).

Phosphoinositide 3-kinase γ mediates chemotactic responses of human eosinophils to platelet-activating factor (2010)
Journal Article
Matar Hasan, A., Mourtada-Maarabouni, M., Hameed, M. S., Williams, G. T., & Dent, G. (2010). Phosphoinositide 3-kinase γ mediates chemotactic responses of human eosinophils to platelet-activating factor. International Immunopharmacology, 10(9), 1017-1021. https://doi.org/10.1016/j.intimp.2010.05.014

Background Eosinophils are characteristic participants in allergic inflammation. The intracellular signalling mechanisms involved in the migration of eosinophils to sites of allergic inflammation are poorly understood. Chemotactic responses of eosin... Read More about Phosphoinositide 3-kinase γ mediates chemotactic responses of human eosinophils to platelet-activating factor.