All Outputs (5)

The potential of magnetic hyperthermia for triggering the differentiation of cancer cells (2018)
Journal Article
Moise, S., Byrne, J. M., El Haj, A. J., & Telling, N. D. (2018). The potential of magnetic hyperthermia for triggering the differentiation of cancer cells. Nanoscale, 10(44), 20519-20525. https://doi.org/10.1039/c8nr05946b

Magnetic hyperthermia is a potential technique for cancer therapy that exploits heat generated by magnetic nanoparticles to kill cancerous cells. Many studies have shown that magnetic hyperthermia is effective at killing cancer cells both in vitro an... Read More about The potential of magnetic hyperthermia for triggering the differentiation of cancer cells.

Alternating current (AC) susceptibility as a particle-focused probe of coating and clustering behaviour in magnetic nanoparticle suspensions. (2018)
Journal Article
Narayanasamy, K. K., Cruz-Acuña, M., Rinaldi, C., Everett, J., Dobson, J., & Telling, N. (2018). Alternating current (AC) susceptibility as a particle-focused probe of coating and clustering behaviour in magnetic nanoparticle suspensions. Journal of Colloid and Interface Science, 532, 536 - 545. https://doi.org/10.1016/j.jcis.2018.08.014

HYPOTHESIS: The functionality of magnetic nanoparticles (MNPs) relies heavily on their surface coating, which in turn affects the interactions between MNPs, and the formation of single-core particles or multi-core clusters. In this study we assessed... Read More about Alternating current (AC) susceptibility as a particle-focused probe of coating and clustering behaviour in magnetic nanoparticle suspensions..

Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer’s disease subjects (2018)
Journal Article
Everett, J., Collingwood, J. F., Tjendana-Tjhin, V., Brooks, J., Lermyte, F., Plascencia-Villa, G., …Telling, N. D. (2018). Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer’s disease subjects. Nanoscale, 10(25), 11782-11796. https://doi.org/10.1039/c7nr06794a

Altered metabolism of biometals in the brain is a key feature of Alzheimer's disease, and biometal interactions with amyloid-ß are linked to amyloid plaque formation. Iron-rich aggregates, including evidence for the mixed-valence iron oxide magnetite... Read More about Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer’s disease subjects.

Translation of remote control regenerative technologies for bone repair. (2018)
Journal Article
Markides, H., McLaren, J. S., Telling, N. D., Alom, N., Al-Mutheffer, E. A., Oreffo, R. O., …El Haj, A. J. (2018). Translation of remote control regenerative technologies for bone repair. npj Regenerative Medicine, 3, Article 9. https://doi.org/10.1038/s41536-018-0048-1

The role of biomechanical stimuli, or mechanotransduction, in normal bone homeostasis and repair is understood to facilitate effective osteogenesis of mesenchymal stem cells (MSCs) in vitro. Mechanotransduction has been integrated into a multitude of... Read More about Translation of remote control regenerative technologies for bone repair..

Dynamical Magnetic Response of Iron Oxide Nanoparticles Inside Live Cells (2018)
Journal Article
Cabrera, D., Coene, A., Leliaert, J., Artés-Ibáñez, E. J., Dupré, L., Telling, N. D., & Teran, F. J. (2018). Dynamical Magnetic Response of Iron Oxide Nanoparticles Inside Live Cells. ACS nano, 12(3), 2741-2752. https://doi.org/10.1021/acsnano.7b08995

Magnetic nanoparticles exposed to alternating magnetic fields have shown a great potential acting as magnetic hyperthermia mediators for cancer treatment. However, a dramatic and unexplained reduction of the nanoparticle magnetic heating efficiency h... Read More about Dynamical Magnetic Response of Iron Oxide Nanoparticles Inside Live Cells.