All Outputs (4)

Systematic Review of miRNA as Biomarkers in Alzheimer's Disease. (2019)
Journal Article
Wragg. (2019). Systematic Review of miRNA as Biomarkers in Alzheimer's Disease. Molecular Neurobiology, 6156 - 6167. https://doi.org/10.1007/s12035-019-1500-y

Currently there are 850,000 people with Alzheimer's disease in the UK, with an estimated rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of amyloid-beta plaques and hyperphosphorylated tau in the brain causing a... Read More about Systematic Review of miRNA as Biomarkers in Alzheimer's Disease..

Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. (2019)
Journal Article
Gwyer, D., Wragg, N. M., & Wilson, S. L. (2019). Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell and Tissue Research, 377, 153 - 159. https://doi.org/10.1007/s00441-019-03016-8

There is a current need for a therapy that can alleviate the social and economic burden that presents itself with debilitating and recurring musculoskeletal soft tissue injuries and disorders. Currently, several therapies are emerging and undergoing... Read More about Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing..

A critical review of current progress in 3D kidney biomanufacturing: advances, challenges, and recommendations (2019)
Journal Article
Wragg, N., Burke, L., & Wilson, S. L. (2019). A critical review of current progress in 3D kidney biomanufacturing: advances, challenges, and recommendations. Renal Replacement Therapy, 5, Article 18. https://doi.org/10.1186/s41100-019-0218-7

The widening gap between organ availability and need is resulting in a worldwide crisis, particularly concerning kidney transplantation. Regenerative medicine options are becoming increasingly advanced and are taking advantage of progress in novel ma... Read More about A critical review of current progress in 3D kidney biomanufacturing: advances, challenges, and recommendations.

Rotator Cuff Repair Augmentation Using Osteoinductive Growth Factors (2019)
Journal Article
Wragg. (2019). Rotator Cuff Repair Augmentation Using Osteoinductive Growth Factors. SN Comprehensive Clinical Medicine, 267 - 276. https://doi.org/10.1007/s42399-019-0041-z

Rotator cuff injuries (RCIs) present a major health problem due to high incidences of degenerative tears greater than 3 cm and prevalence of re-tears following surgical procedures. Since healing and functional restoration relies upon bone ingrowth in... Read More about Rotator Cuff Repair Augmentation Using Osteoinductive Growth Factors.