All Outputs (2)

Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice (2014)
Journal Article
Kehoe, O., Kalia, N., King, S., Eustace, A., Middleton, J., Boyes, C., …Patterson, A. (2014). Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice. Arthritis Research and Therapy, R148 -?. https://doi.org/10.1186/ar4610

INTRODUCTION: Syndecans are heparan sulphate proteoglycans expressed by endothelial cells. Syndecan-3 is expressed by synovial endothelial cells of rheumatoid arthritis (RA) patients where it binds chemokines, suggesting a role in leukocyte trafficki... Read More about Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice.

Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis (2014)
Journal Article
Kehoe, O., Cartwright, A., Askari, A., El Haj, A., & Middleton, J. (2014). Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis. Journal of Translational Medicine, 157 - ?. https://doi.org/10.1186/1479-5876-12-157

BACKGROUND: Rheumatoid arthritis (RA) is a debilitating and painful disease leading to increased morbidity and mortality and novel therapeutic approaches are needed. The purpose of this study was to elucidate if mesenchymal stem cells (MSCs) injected... Read More about Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis.