All Outputs (4)

Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis. (2017)
Journal Article
Chapman, V., Markides, H., Sagar, D., Xu, L., Kay, A., Burston, J., …El Haj, A. (2017). Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis. Stem Cells International, 2905104 - ?. https://doi.org/10.1155/2017/2905104

Background: Mesenchymal stem cells (MSCs) have a therapeutic potential for the treatment of osteoarthritic (OA) joint pathology and pain. The aims of this study were to determine the influence of a passage number on the effects of MSCs on pain behavi... Read More about Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis..

Mesenchymal Stem Cell- Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis (2017)
Journal Article
Kay, A., Long, G., Broadfoot, S., Piccinini, A., Middleton, J., Kehoe, O., …Stefan, A. (2017). Mesenchymal Stem Cell- Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis. Scientific reports, https://doi.org/10.1038/s41598-017-18144-w

We evaluated the therapeutic potential of mesenchymal stem cell-conditioned medium (CM-MSC) as an alternative to cell therapy in an antigen-induced model of arthritis (AIA). Disease severity and cartilage loss were evaluated by histopathological anal... Read More about Mesenchymal Stem Cell- Conditioned Medium Reduces Disease Severity and Immune Responses in Inflammatory Arthritis.

An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. (2017)
Journal Article
Rump, L., Mattey, D. L., Kehoe, O., & Middleton, J. (2017). An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine, 133 - 140. https://doi.org/10.1016/j.cyto.2017.05.023

Rheumatoid arthritis (RA) is a destructive and chronic autoimmune inflammatory disease. Synovial inflammation is a major feature of RA and is associated with leukocyte recruitment. Leukocytes cross the endothelial cells (ECs) into the synovial tissue... Read More about An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium..

An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium (2017)
Journal Article
Rump, L., Mattey, D. L., Kehoe, O., & Middleton, J. (2017). An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine, 97, 133-140. https://doi.org/10.1016/j.cyto.2017.05.023

Rheumatoid arthritis (RA) is a destructive and chronic autoimmune inflammatory disease. Synovial inflammation is a major feature of RA and is associated with leukocyte recruitment. Leukocytes cross the endothelial cells (ECs) into the synovial tissue... Read More about An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium.