Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene
(1998)
Journal Article
Shiau, A., Yang, H., Wu, P., & Wu, C. (1998). Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene. Gene Therapy, 5, 1571–1574. https://doi.org/10.1038/sj.gt.3300757
The E. coli cytosine deaminase (CD) provides a negative selection system for suicide gene therapy as CD transfectants are eliminated following 5-fluorocytosine (5FC) treatment. Here we report a positive selection system for the CD gene using 5-fluoro... Read More about Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene.