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All Outputs (62)

Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time (2022)
Journal Article
Fryer, A. A., Holland, D., Stedman, M., Duff, C. J., Green, L., Scargill, J., …Heald, A. H. (2022). Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time. Journal of Diabetes Research, 2022, 1 - 11. https://doi.org/10.1155/2022/7093707

Aims. We previously showed that the glycated haemoglobin (HbA1c) testing frequency links to diabetes control. Here, we examine the effect of variability in test interval, adjusted for the frequency, on change in HbA1c (delta HbA1c). Materials & Metho... Read More about Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time.

In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology (2022)
Journal Article
Wu, P., V. Sharma, G., S. Mehta, L., Chew-Graham, C., P. Lundberg, G., A. Nerenberg, K., …A. Mamas, M. (2022). In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology. Journal of the American Heart Association, 11(5), Article ARTN e022658. https://doi.org/10.1161/JAHA.121.022658

Background Assisted reproductive technology (ART) has emerged as a common treatment option for infertility, a problem that affects an estimated 48 million couples worldwide. Advancing maternal age with increasing prepregnancy cardiovascular risk fact... Read More about In‐Hospital Complications in Pregnancies Conceived by Assisted Reproductive Technology.

The impact of Charlson Comorbidity Index on de novo CIED procedural outcomes in the United States (2022)
Journal Article
Rashid, Mamas, & Wu. (2022). The impact of Charlson Comorbidity Index on de novo CIED procedural outcomes in the United States. Mayo Clinic Proceedings, 88-100. https://doi.org/10.1016/j.mayocp.2021.06.029

Objective To investigate the utility of Charlson comorbidity index (CCI) as a measure of comorbidity burden to predict procedural outcomes after de novo cardiac implantable electronic device (CIED) implantation. Methods All de novo CIED implantati... Read More about The impact of Charlson Comorbidity Index on de novo CIED procedural outcomes in the United States.

The Impact of Charlson Comorbidity Index on De Novo Cardiac Implantable Electronic Device Procedural Outcomes in the United States (2021)
Journal Article
Mohamed, M. O., Van Spall, H. G., Morillo, C., Wilton, S. B., Kontopantelis, E., Rashid, M., …Mamas, M. (2022). The Impact of Charlson Comorbidity Index on De Novo Cardiac Implantable Electronic Device Procedural Outcomes in the United States. Mayo Clinic Proceedings, 97(1), 88 - 100. https://doi.org/10.1016/j.mayocp.2021.06.029

OBJECTIVE: To investigate the utility of Charlson comorbidity index (CCI) as a measure of comorbidity burden to predict procedural outcomes after de novo cardiac implantable electronic device (CIED) implantation. METHODS: All de novo CIED implantatio... Read More about The Impact of Charlson Comorbidity Index on De Novo Cardiac Implantable Electronic Device Procedural Outcomes in the United States.

The Variability In Glycosylated Haemoglobin (HbA1c) Testing Interval In People With Diabetes Is Linked To Long-Term Diabetes Control, Independent of HbA1c Test Interval (2021)
Journal Article
Heald, A., Holland, D., Stedman, M., Duff, C. J., Green, L., Scargill, J., …Fryer, A. A. (in press). The Variability In Glycosylated Haemoglobin (HbA1c) Testing Interval In People With Diabetes Is Linked To Long-Term Diabetes Control, Independent of HbA1c Test Interval. Endocrine, https://doi.org/10.1530/endoabs.77.p64

Worldwide guidance advocates regular HbA1c testing for people with diabetes mellitus, usually 2-4/yr. We previously showed that HbA1c testing frequency is linked to outcome in terms of HbA1c control. Here we examine the effect of variability (standar... Read More about The Variability In Glycosylated Haemoglobin (HbA1c) Testing Interval In People With Diabetes Is Linked To Long-Term Diabetes Control, Independent of HbA1c Test Interval.

Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing: implications for diabetes management and diagnosis. (2021)
Journal Article
Holland, D., Heald, A. H., Stedman, M., Hanna, F., Wu, P., Duff, C., …Fryer, A. A. (2021). Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing: implications for diabetes management and diagnosis. Journal of Clinical Pathology, 76(3), https://doi.org/10.1136/jclinpath-2021-207776

AIMS: The COVID-19 pandemic, and the focus on mitigating its effects, has disrupted diabetes healthcare services worldwide. We aimed to quantify the effect of the pandemic on diabetes diagnosis/management, using glycated haemoglobin (HbA1c) as surrog... Read More about Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing: implications for diabetes management and diagnosis..

The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients (2021)
Journal Article
Su, Y., Chen, Y., Tseng, Y., Shieh, G., Wu, P., Shiau, A., & Wu, C. (2021). The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients. Cells, 10(10), Article 2642. https://doi.org/10.3390/cells10102642

The embryonic stem cell marker Oct4 is expressed in several human cancers and is positively correlated with a poor outcome in cancer patients. However, its physiological role in cancer progression remains poorly understood. Tumor cells block apoptosi... Read More about The Pro-Survival Oct4/Stat1/Mcl-1 Axis Is Associated with Poor Prognosis in Lung Adenocarcinoma Patients.

The Fourth Trimester: Pregnancy as a Predictor of Cardiovascular Disease (2021)
Journal Article
Wu, P., Park, K., & Gulati, M. (2021). The Fourth Trimester: Pregnancy as a Predictor of Cardiovascular Disease. European Cardiology Review, 16, Article e31. https://doi.org/10.15420/ecr.2021.18

Pregnancy identifies women who may be at a greater risk of cardiovascular disease (CVD), based on the development of adverse pregnancy outcomes (APOs), and may identify women who may benefit from atherosclerotic CVD (ASCVD) risk reduction efforts. AP... Read More about The Fourth Trimester: Pregnancy as a Predictor of Cardiovascular Disease.

In-Hospital Complications in Pregnant Women With Current or Historical Cancer Diagnoses (2021)
Journal Article
Wu, P., P. Jordan, K., A. Chew-Graham, C., O. Mohamed, M., Barac, A., P. Lundberg, G., …A. Mamas, M. (2021). In-Hospital Complications in Pregnant Women With Current or Historical Cancer Diagnoses. Mayo Clinic Proceedings, 96(11), 2779-2792. https://doi.org/10.1016/j.mayocp.2021.03.038

Objective To assess the temporal trends, patient characteristics and comorbidities, and in-hospital cardiovascular and obstetric complications and outcomes of pregnant women with current or historical cancer diagnosis at the time of admission for de... Read More about In-Hospital Complications in Pregnant Women With Current or Historical Cancer Diagnoses.

Inadequate post-partum screening for type 2 diabetes in women with previous gestation diabetes mellitus: a retrospective audit of practice over 17 years. (2021)
Journal Article
Ward, R. J., Fryer, A. A., Hanna, F. W., Spencer, N., Mahmood, M., Wu, P., …Duff, C. J. (2021). Inadequate post-partum screening for type 2 diabetes in women with previous gestation diabetes mellitus: a retrospective audit of practice over 17 years. International Journal of Clinical Practice, e14447 - ?. https://doi.org/10.1111/ijcp.14447

INTRODUCTION: Women with gestational diabetes (GDM) are at greatly increased risk of type 2 diabetes (T2DM). The UK guidance recommends screening for T2DM at around 6 weeks post-partum and annually thereafter. We evaluated conformity to this guidance... Read More about Inadequate post-partum screening for type 2 diabetes in women with previous gestation diabetes mellitus: a retrospective audit of practice over 17 years..

Investigation of polycystic ovarian syndrome: variation in practice and impact on the speed of diagnosis (2021)
Journal Article
Karia, A. M., Duff, C. J., Heald, A. H., Britton, I., Fryer, A. A., & Wu, P. (2021). Investigation of polycystic ovarian syndrome: variation in practice and impact on the speed of diagnosis. Cardiovascular Endocrinology & Metabolism, 10(2), 120-124. https://doi.org/10.1097/xce.0000000000000245

Objective Accurate diagnosis of polycystic ovarian syndrome (PCOS) enables clinical interventions/cardiometabolic risk factor management. Diagnosis can take over 2 years and multiple clinician contacts. We examined patterns of PCOS-associated biochem... Read More about Investigation of polycystic ovarian syndrome: variation in practice and impact on the speed of diagnosis.

Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID-19-related infections, hospital admissions and mortality (2020)
Journal Article
Heald, A. H., Stedman, M., Tian, Z., Wu, P., & Fryer, A. A. (2021). Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID-19-related infections, hospital admissions and mortality. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13768

Introduction The rapid spread of the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV26 2/)(COVID-19) virus resulted in governments around the world instigating a range of measures, including mandating the wearing of... Read More about Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID-19-related infections, hospital admissions and mortality.

Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes (2020)
Journal Article
Wu. (2020). Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes. Clinical Science, 134(18), 2435 - 2445. https://doi.org/10.1042/CS20200147

High-risk pregnancies, such as pregnancies with gestational diabetes mellitus (GDM), are becoming more common and as such, have become important public health issues worldwide. GDM increases the risks of macrosomia, premature infants, and preeclampsi... Read More about Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes.

Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy (2020)
Journal Article
Wu, P., Jordan, K. P., Chew‐Graham, C. A., Coutinho, T., Lundberg, G. P., Park, K. E., …Mamas, M. A. (2020). Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy. Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 9(15), https://doi.org/10.1161/JAHA.120.016182

Background Stroke is a serious complication of hypertensive disorders of pregnancy (HDP), with potentially severe and long-term sequelae. However, the temporal trends, predictors and outcomes of stroke in women with HDP at delivery remain unknown.... Read More about Temporal Trends in Pregnancy‐Associated Stroke and Its Outcomes Among Women With Hypertensive Disorders of Pregnancy.