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Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review. (2024)
Journal Article
Wynne-Jones, G., Wainwright, E., Goodson, N., Jordan, J., Legha, A., Parchment, M., …Peat, G. (2024). Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review. Journal of Occupational Rehabilitation, https://doi.org/10.1007/s10926-024-10205-y

It is difficult to predict which employees, in particular those with musculoskeletal pain, will return to work quickly without additional vocational advice and support, which employees will require this support and what levels of support are most app... Read More about Prognostic Factors and Models for Predicting Work Absence in Adults with Musculoskeletal Conditions Consulting a Healthcare Practitioner: A Systematic Review..

Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study (2024)
Journal Article
Lumley, S., Yu, D., Wilkie, R., Jordan, K. P., & Peat, G. (2024). Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study. Primary Health Care Research & Development, 25, 1-8. https://doi.org/10.1017/S1463423624000070

Background: Chronic musculoskeletal pain and anxiety/depression are significant public health problems. We hypothesised that adults with both conditions constitute a group at especially high risk of future cardiovascular health outcomes. Aim: To... Read More about Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study.

Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50 (2024)
Journal Article
Lynch, M., Bucknall, M., Jagger, C., Kingston, A., & Wilkie, R. (2024). Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50. Scientific Reports, 14(1), Article 5936. https://doi.org/10.1038/s41598-024-53095-z

Although retirement ages are rising in the United Kingdom and other countries, the average number of years people in England can expect to spend both healthy and work from age 50 (Healthy Working Life Expectancy; HWLE) is less than the number of year... Read More about Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50.

The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. (2024)
Journal Article
Parmar, S. S., Mohamed, M. O., Mamas, M. A., & Wilkie, R. (in press). The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients. Expert Review of Cardiovascular Therapy, 22(1-3), 1-9. https://doi.org/10.1080/14779072.2024.2311696

The prevalence of osteoarthritis (OA) and cardiovascular disease are increasing and both conditions share similar risk factors. We investigated the association between OA and receipt of invasive managements and clinical outcomes in patients with acut... Read More about The clinical characteristics, managements, and outcomes of acute myocardial infarction in osteoarthritis patients; a cross-sectional analysis of 6.5 million patients..

Work Ability in the Year after Rehabilitation—Results from the RehabNytte Cohort (2023)
Journal Article
Skinnes, M. N., Moe, R. H., Johansen, T., Lyby, P. S., Eid, I., Fagertun, T. C., …Dahl, K. (in press). Work Ability in the Year after Rehabilitation—Results from the RehabNytte Cohort. Journal of Clinical Medicine, 12(23), Article 7391. https://doi.org/10.3390/jcm12237391

Background: There is limited knowledge regarding the impact of rehabilitation on work ability. The aim of this study was to explore factors associated with work ability 12 months following a multidisciplinary rehabilitation program in a cohort with d... Read More about Work Ability in the Year after Rehabilitation—Results from the RehabNytte Cohort.

Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017 (2023)
Journal Article
Yu, D., Huang, X., Mamas, M., & Wilkie, R. (2023). Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017. RMD Open, 9(3), Article e003298. https://doi.org/10.1136/rmdopen-2023-003298

Objectives: To compare the annual and period prevalence of modifiable cardiovascular risk factors (MCVRFs) between populations with and without osteoarthritis (OA) in the UK over 25 years. Methods: 215 190 patients aged 35 years and over from the... Read More about Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992–2017.

Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain (2023)
Journal Article
Lynch, M., Peat, G., Jordan, K., Yu, D., & Wilkie, R. (2023). Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain. European Journal of Pain, https://doi.org/10.1002/ejp.2148

Background Chronic pain affects up to half of UK adults, impacting quality of life and demand on local health services. Whilst local health planning is currently based on subnational prevalence estimates, associations between pain and sociodemograph... Read More about Where does it hurt? Small area estimates and inequality in the prevalence of chronic pain.

Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019 (2022)
Journal Article
Yu, D., Jordan, K. P., Wilkie, R., Bailey, J., Fitzpatrick, J., Ali, N., …Peat, G. (2022). Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019. Rheumatology Advances in Practice, 7(1), https://doi.org/10.1093/rap/rkac106

Objective To determine whether socioeconomic inequalities in primary care consultation rates for two major, disabling musculoskeletal conditions in England narrowed or widened between 2004-2019. Methods We analysed data from Clinical Practice Re... Read More about Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004-2019.

2021 EULAR points to consider to support people with rheumatic and musculoskeletal diseases to participate in healthy and sustainable paid work (2022)
Journal Article
Boonen, A., Webers, C., Butink, M., Barten, B., Betteridge, N., Black, D. C., …Verstappen, S. M. M. (2023). 2021 EULAR points to consider to support people with rheumatic and musculoskeletal diseases to participate in healthy and sustainable paid work. Annals of the Rheumatic Diseases, 82(1), 57-64. https://doi.org/10.1136/ard-2022-222678

As part of its strategic objectives for 2023, EULAR aims to improve the work participation of people with rheumatic and musculoskeletal diseases (RMDs). One strategic initiative focused on the development of overarching points to consider (PtC) to s... Read More about 2021 EULAR points to consider to support people with rheumatic and musculoskeletal diseases to participate in healthy and sustainable paid work.

Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness (2022)
Journal Article
Peat, G., Jordan, K., Wilkie, R., Corp, N., Van Der Windt, D., Yu, D., …Ali, N. (2022). Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness. Journal of Public Health, 44(3), e376–e387. https://doi.org/10.1093/pubmed/fdac014

Background It is unclear whether seven interventions recommended by Public Health England for preventing and managing common musculoskeletal conditions reduce or widen health inequalities in adults with musculoskeletal conditions. Methods We used cit... Read More about Do recommended interventions widen or narrow inequalities in musculoskeletal health? An equity-focussed systematic review of differential effectiveness.

Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases (2022)
Journal Article
Yu, D., Missen, M., P Jordan, K., Edwards, J., Bailey, J., Wilkie, R., …Peat, G. (2022). Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases. Clinical Epidemiology, 14, 179-189. https://doi.org/10.2147/CLEP.S337323

Purpose: To compare estimates of annual person-consulting incidence and prevalence of low back pain (LBP) and osteoarthritis for two national English electronic health record databases (Clinical Practice Research Datalink (CPRD) Aurum and CPRD GOLD).... Read More about Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases.

Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations (2022)
Journal Article
Lynch, M., Bucknall, M., Jagger, C., & Wilkie, R. (2022). Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations. Scientific reports, 12(1), Article 2408. https://doi.org/10.1038/s41598-022-06490-3

Retirement ages are rising in many countries to offset the challenges of population ageing, but osteoarthritis is an age-associated disease that is becoming more prevalent and may limit capacity to work until older ages. We aimed to assess the impact... Read More about Healthy working life expectancy at age 50 for people with and without osteoarthritis in local and national English populations.

Projections of healthy working life expectancy in England to the year 2035 (2022)
Journal Article
Wilkie, Bucknall, & Lynch. (2022). Projections of healthy working life expectancy in England to the year 2035. https://doi.org/10.1038/s43587-021-00161-0

UK state pension age is rising in response to life expectancy gains but population health and job opportunities may not be sufficient to achieve extended working lives1,2,3. This study aimed to estimate future trends in healthy working life expectanc... Read More about Projections of healthy working life expectancy in England to the year 2035.

Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies. (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies. Journal of Diabetes and Clinical Research, 3(3), https://doi.org/10.33696/diabetes.3.042

Background: People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opportunities... Read More about Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies..

338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study (2021)
Journal Article
Yu, D., Jordan, K., Bailey, J., Peat, G., & Wilkie, R. (2021). 338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study. International Journal of Epidemiology, 50(Supplement_1), https://doi.org/10.1093/ije/dyab168.739

Background Patient Reported Outcome Measures (PROM) collected in surveys allow understanding of the health at the population-level. We aimed to test the feasibility of estimating health status as measured by PROMs through ecological prediction model... Read More about 338 Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study.

496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis (2021)
Journal Article
Huang, M., Yu, D., Wilkie, R., & Mamas, M. (2021). 496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis. International Journal of Epidemiology, i105 - i105. https://doi.org/10.1093/ije/dyab168.295

Abstract Background Osteoarthritis (OA) has a major impact on the global burden of disease and is associated with poorer cardiovascular disease (CVD) outcomes. However it’s unclear whether people with OA have higher long-term (10-year) CVD risk comp... Read More about 496Higher predicted 10-year risk for cardiovascular disease in primary care consulters for osteoarthritis.

Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies (2021)
Journal Article
Huang, X., Wilkie, R., Mamas, M., & Yu, D. (2021). Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies. MedRxiv, https://doi.org/10.1101/2021.02.14.21251130v1

Background People with osteoarthritis are at a high risk of cardiovascular disease (CVD). Detecting CVD risk factors in this high-risk population will help to improve CVD outcomes. Primary care electronic health records (EHRs) provide opportunities f... Read More about Prevalence of cardiovascular risk factors in osteoarthritis patients derived from primary care records: a systematic review of observational studies.

Estimating the population health burden of musculoskeletal conditions using primary care electronic health records (2021)
Journal Article
Yu, D., Peat, G., Jordan, K., Bailey, J., Prieto-Alhambra, D., Robinson, D., …Wilkie, R. (2021). Estimating the population health burden of musculoskeletal conditions using primary care electronic health records. Rheumatology, 60(10), 4832-4843. https://doi.org/10.1093/rheumatology/keab109

Objectives Better indicators from affordable, sustainable data sources are needed to monitor population burden of musculoskeletal conditions. We propose five indicators of musculoskeletal health and assessed if routinely available primary care elect... Read More about Estimating the population health burden of musculoskeletal conditions using primary care electronic health records.

The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction (2020)
Journal Article
Parmar, S., Mohamed, M., Wilkie, R., & Mamas, M. (2020). The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction. European Heart Journal, 41(S2), 1660 - 1660. https://doi.org/10.1093/ehjci/ehaa946.1660

Background People with osteoarthritis (OA) have an increased risk of cardiovascular disease, including acute myocardial infarction (AMI). Despite OA being the most common joint condition and the fastest increasing major health condition, there is li... Read More about The association between osteoarthritis and invasive treatment and clinical outcomes in 6.5 million patients presenting with acute myocardial infarction.