All Outputs (2)

Adrenoceptor Desensitization: Current Understanding of Mechanisms. (2024)
Journal Article
Maaliki, D., Jaffa, A. A., Nasser, S., Sahbekar, A., & Eid, A. H. (2024). Adrenoceptor Desensitization: Current Understanding of Mechanisms. Pharmacological Reviews, 76(3), 358-387. https://doi.org/10.1124/pharmrev.123.000831

G-protein coupled receptors (GPCRs) transduce a wide range of extracellular signals. They are key players in the majority of biological functions including vision, olfaction, chemotaxis and immunity. However, as essential as most of them are to body... Read More about Adrenoceptor Desensitization: Current Understanding of Mechanisms..

C-peptide in diabetes: A player in a dual hormone disorder? (2024)
Journal Article
Dakroub, A., Dbouk, A., Asfour, A., Nasser, S. A., El‐Yazbi, A. F., Sahebkar, A., …Eid, A. A. (in press). C-peptide in diabetes: A player in a dual hormone disorder?. Journal of Cellular Physiology, 10.1002/jcp.31212. https://doi.org/10.1002/jcp.31212

C-peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C-peptide serves an anti-inflammatory and anti-atherogenic role in type 1 diabetes mellitus (T1DM) and early T2DM. C-peptide pro... Read More about C-peptide in diabetes: A player in a dual hormone disorder?.