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An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels (2021)
Journal Article
de Leon, J., Schoretsanitis, G., Smith, R. L., Molden, E., Solismaa, A., Seppälä, N., …Marder, S. R. (2021). An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels. Pharmacopsychiatry, 55(02), 73-86. https://doi.org/10.1055/a-1625-6388

This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that clozapine is the third most toxic drug in the United States (US), and... Read More about An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels.

Suicide, self-harm and suicidal ideation during COVID-19: A systematic review (2021)
Journal Article
Farooq, S., Tunmore, J., Ali, W., & Ayub, M. (2021). Suicide, self-harm and suicidal ideation during COVID-19: A systematic review. Psychiatry Research, 306, Article ARTN 114228. https://doi.org/10.1016/j.psychres.2021.114228

We aimed to do a systematic review and meta-analysis of studies describing suicidal ideation, suicide attempts and suicide and associated risk factors during COVID-19 pandemic. We searched following electronic databases using relevant search terms: M... Read More about Suicide, self-harm and suicidal ideation during COVID-19: A systematic review.

The haematological side effects of clozapine: literature review and meta-analysis (2021)
Journal Article
Munshi, T., Naeem, F., Ayub, M., Farooq, S., Khachatryan, D., Asmer, S., …Fairbairn, J. (2021). The haematological side effects of clozapine: literature review and meta-analysis. BJPsych Open, 7(S1), https://doi.org/10.1192/bjo.2021.729

Aims This review and meta-analysis aim to estimate the cumulative incidence of clozapine induced agranulocytosis and leukopenia the impact of the associated factors such as dose of clozapine, duration of follow-up, gender and race on the cumulative... Read More about The haematological side effects of clozapine: literature review and meta-analysis.

Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data (2021)
Journal Article
Farooq. (2021). Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data. BMJ Open, 1-9. https://doi.org/10.1136/bmjopen-2020-042331

Introduction Individuals with schizophrenia are at a high risk of physical health comorbidities and premature mortality. Cardiovascular and metabolic causes are an important contributor. There are gaps in monitoring, documenting and managing these ph... Read More about Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data.

Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives (2021)
Journal Article
Nash, A., Kingstone, T., Farooq, S., Tunmore, J., & Chew-Graham, C. A. (2021). Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives. BMJ Open, e042497 - ?. https://doi.org/10.1136/bmjopen-2020-042497

OBJECTIVES: The side effects of antipsychotic medications (APs) can increase the risk of developing physical health conditions. Some APs pose a higher risk than others. Evidence suggests switching to lower risk APs can support physical health outcome... Read More about Switching antipsychotics to support the physical health of people with severe mental illness: A qualitative study of healthcare professionals' perspectives.