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All Outputs (13)

275 PATIENTS LIVING IN AREAS OF HIGHER SOCIOECONOMIC AREA DEPRIVATION HAVE SIGNIFICANTLY POORER PATIENT-REPORTED OUTCOMES FOLLOWING AUTOLOGOUS CHONDROCYTE IMPLANTATION IN THE UNITED KINGDOM (2024)
Presentation / Conference Contribution
Ismael, S., McCarthy, H. S., Williams, M., Barnett, A., Gallacher, P., Jermin, P., Richardson, J., Wright, K. T., Roberts, S., & Kuiper, J. H. (2024, April). 275 PATIENTS LIVING IN AREAS OF HIGHER SOCIOECONOMIC AREA DEPRIVATION HAVE SIGNIFICANTLY POORER PATIENT-REPORTED OUTCOMES FOLLOWING AUTOLOGOUS CHONDROCYTE IMPLANTATION IN THE UNITED KINGDOM. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

284 Lower Cell Number Implanted is Consistently Associated with Improved Functional Outcome Post-Autologous Chondrocyte Implantation in Longitudinal Multilevel Modelling Analyses. (2024)
Presentation / Conference Contribution
Kuiper, J. H., Dewan, V., Tierney, L., Roberts, S., Harrison, P., Gallacher, P., Jermin, P., Snow, M., & Wright, K. T. (2024, April). 284 Lower Cell Number Implanted is Consistently Associated with Improved Functional Outcome Post-Autologous Chondrocyte Implantation in Longitudinal Multilevel Modelling Analyses. Poster presented at 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria

Analysis of Synovial Fluid Proteomes After Treating an Ovine Osteoarthritic Model with Human Umbilical Cord Mesenchymal Stem Cells (2023)
Presentation / Conference Contribution
McDonald, J., Wright, K., Mennan, C., Peffers, M., Perry, J., Roberts, S., Newall, K., Henson, F., & Hulme, C. (2023, September). Analysis of Synovial Fluid Proteomes After Treating an Ovine Osteoarthritic Model with Human Umbilical Cord Mesenchymal Stem Cells. Presented at International Cartilage and Joint Preservation Society World Congress 2023, Melia Hotel Sitges, Sitges/ Barcelona

Umbilical Cord MSC Treated Osteoarthritic Sheep Display Reduced Radiographic Changes: Proteomic Biomarker Profiling of Synovial Fluids Implicate an Immunomodulatory Mechanism (2023)
Presentation / Conference Contribution
Perry, J., Mennan, C., Cool, P., Mccarthy, H., Newell, K., Hulme, C., Wright, K., Mcdonald, J., Peffers, M., Henson, F., & Roberts, S. (2023, March). Umbilical Cord MSC Treated Osteoarthritic Sheep Display Reduced Radiographic Changes: Proteomic Biomarker Profiling of Synovial Fluids Implicate an Immunomodulatory Mechanism. Presented at TERMIS 2023 – European Chapter, Manchester Central Conference Centre Manchester, UK

Matrix mettaloproteinase-3 (MMP-3) and tissue inhibitors of metalloproteinases-1 (TIMP-1): potential biomarkers to predict the outcome of Autologous Chondrocyte Implantation (2019)
Presentation / Conference Contribution
Hulme, C., Roberts, S., Gallacher, P., Jermin, P., Richardson, J., & Wright, K. (2019, October). Matrix mettaloproteinase-3 (MMP-3) and tissue inhibitors of metalloproteinases-1 (TIMP-1): potential biomarkers to predict the outcome of Autologous Chondrocyte Implantation. Paper presented at International Joint and Cartilage Preservation Society (ICRS) 2019, Vancouver, Canada

Assessment of candidate predictive protein biomarkers for microfracture and osteotomy (2018)
Presentation / Conference Contribution
Hulme, C., Richardson, J., Gallacher, P., Roberts, S., & Wright, K. Assessment of candidate predictive protein biomarkers for microfracture and osteotomy. Presented at 2018 OARSI World Congress on Osteoarthritis (26-29 April 2018), ACC Congress Center Liverpool, United Kingdom

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Purpose: Biomarkers that can predict clinical outcome for surgeries to prevent the progression of osteoarthritis (OA) are needed to ensure patients can be better stratified to receive the most appropriate treatment. We have previousl... Read More about Assessment of candidate predictive protein biomarkers for microfracture and osteotomy.

Poor clinical response to Autologous Chondrocyte Implantation is associated with a unique synovial fluid proteome profile (2017)
Presentation / Conference Contribution
Hulme, C., Wilson, E., Peffers, M., Fuller, H., Roberts, S., Simpson, D., Richardson, J., Gallacher, P., & Wright, K. Poor clinical response to Autologous Chondrocyte Implantation is associated with a unique synovial fluid proteome profile. Presented at 2017 OARSI World Congress on Osteoarthritis (27-30 April 2017), Las Vegas, NV, USA

Cartilage harvest elevates sCD14 and MMP-3 in the synovial fluid of the autologous chondrocyte implantation (ACI) treated joint (2017)
Presentation / Conference Contribution
Wright, K. T., Wilson, E., Hulme, C., Kuiper, J. H., Gallacher, P., Richardson, J. B., & Roberts, S. Cartilage harvest elevates sCD14 and MMP-3 in the synovial fluid of the autologous chondrocyte implantation (ACI) treated joint. Presented at British Society for Matrix Biology “The Grey Area – Age and the Extracellular Matrix”

Introduction This study aims to examine the impact of the cartilage harvest procedure on synovial fluid biomarkers at the time of autologous chondrocyte implantation (ACI).

Materials and Methods Hyaluronic acid (HA), cartilage oligomeric matrix pr... Read More about Cartilage harvest elevates sCD14 and MMP-3 in the synovial fluid of the autologous chondrocyte implantation (ACI) treated joint.