Skip to main content

Research Repository

Advanced Search

All Outputs (16)

Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study (2019)
Journal Article
Muller, S., Whittle, R., Hider, S. L., Belcher, J., Helliwell, T., Morton, C., …Mallen, C. D. (2020). Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study. Rheumatology, 59(8), 1906-1915. https://doi.org/10.1093/rheumatology/kez533

Objectives. To investigate potential subgroups of primary care diagnosed patients with polymyalgia rheumatica (PMR) based on self-reported pain and stiffness severity over time. Methods. 652 people with an incident PMR diagnosis were recruited fro... Read More about Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study.

The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis. (2019)
Journal Article
Chen, W. M., Subesinghe, S., Muller, S., Hider, S. L., Mallen, C. D., & Scott, I. C. (2019). The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism, 50(2), 252-260. https://doi.org/10.1016/j.semarthrit.2019.09.003

OBJECTIVE: To establish if gravidity and parity associate with the development of rheumatoid arthritis (RA), and to establish if this effect is influenced by the time elapsed since pregnancy/childbirth, the number of pregnancies/childbirths, and sero... Read More about The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis..

Characteristics of patients with giant cell arteritis who experience visual symptoms (2019)
Journal Article
Shen Chean, C., Prior, J., Helliwell, T., Belcher, J., Mackie, S. L., Hider, S., …Mallen, C. (2019). Characteristics of patients with giant cell arteritis who experience visual symptoms. Rheumatology International, 39, 1789-1796. https://doi.org/10.1007/s00296-019-04422-5

Permanent vision loss is one of the most serious complications of giant cell arteritis (GCA) and therefore prompt diagnosis is paramount. However, diagnosis of GCA remains challenging due to its frequently non-specific presentation. Our aim was to id... Read More about Characteristics of patients with giant cell arteritis who experience visual symptoms.

Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study (2019)
Journal Article
Mallen, Muller, Hider, & Helliwell. (2019). Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study. BMC Medicine, https://doi.org/10.1186/s12916-019-1394-6

Background Antibiotic-induced disturbances of the human microbiota have been implicated in the development of chronic autoimmune conditions. This study aimed to assess whether antibiotic use is associated with the onset of rheumatoid arthritis (RA).... Read More about Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study.

Suspected very early inflammatory rheumatic diseases in primary care. (2019)
Journal Article
Mallen, & Hider. (2019). Suspected very early inflammatory rheumatic diseases in primary care. https://doi.org/10.1016/j.berh.2019.06.00

As primary care clinicians are typically the first point of contact for patients with musculoskeletal problems, they are crucial to the early diagnosis and treatment of patients with an incident inflammatory arthritis, like rheumatoid arthritis. Curr... Read More about Suspected very early inflammatory rheumatic diseases in primary care..

The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study (2019)
Report
Prior, J., Muller, S., Helliwell, T., Hider, S., Barraclough, K., Dasgupta, B., & Mallen, C. (2019). The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study

We aimed to examine the association between pain, stiffness and fatigue in newly diagnosed polymyalgia rheumatica (PMR) patients using baseline data from a prospective cohort study. Fatigue is a known, but often ignored symptom of PMR. Newly diagnose... Read More about The association of pain and stiffness with fatigue in incident polymyalgia rheumatica: baseline results from the polymyalgia rheumatica cohort study.

Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey (2019)
Journal Article
Hider, S. L., Muller, S., Helliwell, T., Prior, J. A., Scott, I., Lawton, S. A., …Mallen, C. D. (2019). Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey. Rheumatology, 58(11), 2009-2014. https://doi.org/10.1093/rheumatology/kez184

Objectives: To describe the prevalence of self-reported inflammatory joint symptoms, such as joint pain, stiffness and swelling in UK primary care patients consulting for both musculoskeletal (MSK) and non-musculoskeletal (non-MSK) complaints. Met... Read More about Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey.

Inflammatory biomarkers do not distinguish between patients with sciatica and referred leg pain within a primary care population: results from a nested study within the ATLAS cohort (2019)
Journal Article
Hider, S. L., Konstantinou, K., Hay, E. M., Glossop, J., & Mattey, D. L. (2019). Inflammatory biomarkers do not distinguish between patients with sciatica and referred leg pain within a primary care population: results from a nested study within the ATLAS cohort. BMC Musculoskeletal Disorders, 20, Article 202. https://doi.org/10.1186/s12891-019-2604-2

Background There is increasing interest in the role of pro-inflammatory cytokines in the pathogenesis of sciatica and whether these could be potential targets for treatment. We sought to investigate serum biomarker levels in patients with low back-r... Read More about Inflammatory biomarkers do not distinguish between patients with sciatica and referred leg pain within a primary care population: results from a nested study within the ATLAS cohort.

216 Characteristics of patients with prevalent giant cell arteritis in UK primary care (2019)
Journal Article
Twomlow, E. L., Prior, J. A., Mackie, S. L., Helliwell, T., Hider, S. L., Belcher, J., …Mallen, C. D. (2019). 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez107.032

Background: Giant cell arteritis (GCA) is a rare, but serious condition affecting older people. Prompt diagnosis remains challenging due to non-specific presentations. Furthermore, there are marked variations in GP referral and management approaches.... Read More about 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care.

E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica (2019)
Journal Article
Morton, C., Muller, S., Hider, S., Belcher, J., Mallen, C. D., & Helliwell, T. (2019). E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez110.041

Background: Extended duration of glucocorticoid (GC) therapy can be considered a poor outcome in people with polymyalgia rheumatica (PMR). Being able to predict the likelihood of extended GC therapy at diagnosis would enable earlier specialist referr... Read More about E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica.

040 The incidence of anxiety or depression in patients with and without inflammatory rheumatic conditions (2019)
Journal Article
Machin, A. R., Hider, S. L., Chew-Graham, C. A., & Bucknall, M. (2019). 040 The incidence of anxiety or depression in patients with and without inflammatory rheumatic conditions. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez106.039

Background: Rheumatoid arthritis (RA) has been linked to several co-morbidities, including anxiety and depression, which can contribute to increased morbidity and mortality. Less literature has examined the association between other inflammatory rheu... Read More about 040 The incidence of anxiety or depression in patients with and without inflammatory rheumatic conditions.

088 The impact of anxiety on quality of life and disease activity in rheumatoid arthritis: a systematic review (2019)
Journal Article
Machin, A. R., Haththotuwa, R., Babatunde, O., Scott, I., Bucknall, M., Corp, N., …Hider, S. L. (2019). 088 The impact of anxiety on quality of life and disease activity in rheumatoid arthritis: a systematic review. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez106.087

Background: Co-morbid anxiety and depression are frequent in patients with rheumatoid arthritis (RA), but are often under-recognised and under-treated, contributing to increased morbidity and mortality. Most studies examining the impact of mood probl... Read More about 088 The impact of anxiety on quality of life and disease activity in rheumatoid arthritis: a systematic review.

E059 Development of a nurse-led integrated care review based in primary care to identify and improve the management of co-morbidities in patients with inflammatory rheumatological conditions: the INCLUDE study (2019)
Journal Article
Machin, A. R., Hider, S. L., Jinks, C., Herron, D., Paskins, Z., Cooke, K., & Chew-Graham, C. A. (2019). E059 Development of a nurse-led integrated care review based in primary care to identify and improve the management of co-morbidities in patients with inflammatory rheumatological conditions: the INCLUDE study. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez110.057

Background: People with inflammatory rheumatological conditions (IRCs) are at an increased risk of common comorbidities such as cardiovascular disease (CVD), osteoporosis, anxiety and depression. These are often not recognised or treated and can lead... Read More about E059 Development of a nurse-led integrated care review based in primary care to identify and improve the management of co-morbidities in patients with inflammatory rheumatological conditions: the INCLUDE study.

Examining management and research priorities in patients with polymyalgia rheumatica: a primary care questionnaire survey. (2019)
Journal Article
Mallen, Muller, Hider, & Bucknall. (2019). Examining management and research priorities in patients with polymyalgia rheumatica: a primary care questionnaire survey. Clinical Rheumatology, 38, 1767-1772. https://doi.org/10.1007/s10067-018-04405-0

INTRODUCTION/OBJECTIVES: Polymyalgia rheumatica (PMR) is a common inflammatory disorder that is usually managed with oral glucocorticoids, which although effective can cause significant adverse events. Support group survey data suggests length of g... Read More about Examining management and research priorities in patients with polymyalgia rheumatica: a primary care questionnaire survey..