All Outputs (4)

Biocatalytic Approaches to Building Blocks for Enzymatic and Chemical Glycan Synthesis (2022)
Journal Article
Cosgrove, Miller, & Dolan. (2022). Biocatalytic Approaches to Building Blocks for Enzymatic and Chemical Glycan Synthesis. JACS Au, 47-61. https://doi.org/10.1021/jacsau.2c00529

While the field of biocatalysis has bloomed over the past 20–30 years, advances in the understanding and improvement of carbohydrate-active enzymes, in particular, the sugar nucleotides involved in glycan building block biosynthesis, have progressed... Read More about Biocatalytic Approaches to Building Blocks for Enzymatic and Chemical Glycan Synthesis.

Frontispiece: Reaching New Biocatalytic Reactivity Using Continuous Flow Reactors (2022)
Journal Article
Cosgrove, S. C., & Mattey, A. P. (in press). Frontispiece: Reaching New Biocatalytic Reactivity Using Continuous Flow Reactors. Chemistry, 28(13), https://doi.org/10.1002/chem.202281361

Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues. (2022)
Journal Article
Cosgrove, S. C., & Miller, G. J. (2022). Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues. Expert Opinion on Drug Discovery, 17(4), 355-364. https://doi.org/10.1080/17460441.2022.2039620

INTRODUCTION: Nucleoside analogues represent a cornerstone of achievement in drug discovery, rising to prominence particularly in the fields of antiviral and anticancer discovery over the last 60 years. Traditionally accessed using chemical synthesis... Read More about Advances in biocatalytic and chemoenzymatic synthesis of nucleoside analogues..

Oxidase enzymes as sustainable oxidation catalysts (2022)
Journal Article
Wahart, A. J. C., Staniland, J., Miller, G. J., & Cosgrove, S. C. (2022). Oxidase enzymes as sustainable oxidation catalysts. Royal Society Open Science, 9(1), https://doi.org/10.1098/rsos.211572

Oxidation is one of the most important processes used by the chemical industry. However, many of the methods that are used pose significant sustainability and environmental issues. Biocatalytic oxidation offers an alternative to these methods, with a... Read More about Oxidase enzymes as sustainable oxidation catalysts.