All Outputs (3)

We may not be buying what the label says on the tin: a cautionary tale from a study of the influence of proteoglycans on nerve growth (2017)
Presentation / Conference Contribution
Owen, S. J., Fuller, H. R., Jones, P., Caterson, B., Shirran, S. L., Botting, C. H., & Roberts, S. (n.d.). We may not be buying what the label says on the tin: a cautionary tale from a study of the influence of proteoglycans on nerve growth [Conference Abstract]. British Society for Matrix Biology Spring 2017 Meeting: Matrix Proteoglycans: active participants in cell-extracellular matrix communication. https://onlinelibrary.wiley.com/doi/10.1111/iep.12235

Introduction

Commercially sourced preparations of reagents are an essential tool for all our laboratory studies and are assumed to have a certain degree of purity. During a study to determine how different proteoglycan substrates might control ner... Read More about We may not be buying what the label says on the tin: a cautionary tale from a study of the influence of proteoglycans on nerve growth.

Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity (2017)
Presentation / Conference Contribution
Mennan, C., Owen, S., Garcia, J., McCarthy, H., Banerjee, R., Roberts, S., & Richardson, J. (2017, March 27-29). Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity [Poster]. British Society for Matrix Biology “The Grey Area – Age and the Extracellular Matrix”, Chester University, Chester, England, UK. https://onlinelibrary.wiley.com/doi/10.1111/iep.12211

Introduction The maintenance of chondrogenic phenotype in human articular chondrocytes grown in continuous normoxic (21% O2) and hypoxic (2% O2) conditions was assessed, with the aim of finding the best environment for culturing cells destined for ca... Read More about Human articular chondrocytes retain their phenotype in sustained hypoxia whilst normoxia promotes their immunomodulatory capacity.

Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines. (2017)
Journal Article
Owen, S., Sharp, C., Broom, N., McCall, I., Roberts, S., Wade, K., & Rodrigues, S. (2017). Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines. European Spine Journal, 248 -258. https://doi.org/10.1007/s00586-016-4560-y

PURPOSE: To investigate the microscopic fibrous integration between the intervertebral disc, cartilage endplates and vertebral endplates in human lumbar spines of varying degrees of degeneration using differential interference contrast (DIC) optics.... Read More about Staying connected: structural integration at the intervertebral disc-vertebra interface of human lumbar spines..