All Outputs (66)

Exploring the Impact of the First Wave of COVID-19 on Social Work Practice: A Qualitative Study in England, UK (2021)
Journal Article
Kingstone, T., Campbell, P., Andras, A., Nixon, K., Mallen, C., Dikomitis, L., …Wenning, B. (2021). Exploring the Impact of the First Wave of COVID-19 on Social Work Practice: A Qualitative Study in England, UK. British Journal of Social Work, 52(4), 2043–2062. https://doi.org/10.1093/bjsw/bcab166

The COVID-19 pandemic signalled a radical shift in health and social care services globally. In UK, many of the people with existing social care needs were identified as 'clinically vulnerable' to COVID-19. Those at greatest risk were encouraged to a... Read More about Exploring the Impact of the First Wave of COVID-19 on Social Work Practice: A Qualitative Study in England, UK.

Prevalence of osteoarthritis in lower middle- and low-income countries: a systematic review and meta-analysis (2021)
Journal Article
Yahaya, I., Wright, T., Babatunde, O., Corp, N., Helliwell, T., Dikomitis, L., & Mallen, C. (2021). Prevalence of osteoarthritis in lower middle- and low-income countries: a systematic review and meta-analysis. Rheumatology International, 41, 1221-1231. https://doi.org/10.1007/s00296-021-04838-y

Evidence from the Global Burden of Disease studies suggests that osteoarthritis (OA) is a significant cause of disability globally; however, it is less clear how much of this burden exists in low-income and lower middle-income countries. This study a... Read More about Prevalence of osteoarthritis in lower middle- and low-income countries: a systematic review and meta-analysis.

Acute Myocardial Infarction in Autoimmune Rheumatological Disease: A Nationwide Analysis of Clinical outcomes and Predictors of Management Strategy (2021)
Journal Article
Mamas, Clarson, Roddy, Mallen, & Helliwell. (2021). Acute Myocardial Infarction in Autoimmune Rheumatological Disease: A Nationwide Analysis of Clinical outcomes and Predictors of Management Strategy. Mayo Clinic Proceedings, 388-399. https://doi.org/10.1016/j.mayocp.2020.04.044

Objectives: The present study sought to examine national-level differences in management strategies and outcomes in patients with autoimmune rheumatic disease (AIRD) with acute myocardial infarction (AMI) between 2004 and 2014. Methods: All AMI hos... Read More about Acute Myocardial Infarction in Autoimmune Rheumatological Disease: A Nationwide Analysis of Clinical outcomes and Predictors of Management Strategy.

Mortality Among Patients With Polymyalgia Rheumatica: A Retrospective Cohort Study (2020)
Journal Article
Partington, R., Muller, S., Mallen, C. D., Abdul Sultan, A., & Helliwell, T. (2021). Mortality Among Patients With Polymyalgia Rheumatica: A Retrospective Cohort Study. Arthritis Care and Research, 73(12), 1853-1857. https://doi.org/10.1002/acr.24403

OBJECTIVE: To determine whether a diagnosis of polymyalgia rheumatica (PMR) is associated with premature mortality. METHODS: We extracted anonymised electronic medical records of patients over the age of 40 years, who were eligible for linkage with t... Read More about Mortality Among Patients With Polymyalgia Rheumatica: A Retrospective Cohort Study.

Comorbidities in patients with polymyalgia rheumatica prior to and following diagnosis: A case control and cohort study (2020)
Journal Article
Partington, R., Muller, S., Mallen, C. D., Abdul Sultan, A., & Helliwell, T. (2020). Comorbidities in patients with polymyalgia rheumatica prior to and following diagnosis: A case control and cohort study. Seminars in Arthritis and Rheumatism, 50(4), 663-672. https://doi.org/10.1016/j.semarthrit.2020.05.003

Objectives: To determine the burden of comorbidities, including glucocorticoid (GC) related adverse effects, in patients with polymyalgia rheumatica (PMR) before and after diagnosis. Methods: We extracted anonymised electronic medical records of p... Read More about Comorbidities in patients with polymyalgia rheumatica prior to and following diagnosis: A case control and cohort study.

THE RELATIONSHIP BETWEEN OBESITY AND OUTCOMES IN PATIENTS WITH POLYMYALGIA RHEUMATICA (2020)
Journal Article
Helliwell, T., Mallen, C. D., Scott, I. C., Bajpai, R., Muller, S., & Hider, S. L. (2020). THE RELATIONSHIP BETWEEN OBESITY AND OUTCOMES IN PATIENTS WITH POLYMYALGIA RHEUMATICA. Rheumatology, 59, 18-18. https://doi.org/10.1093/RHEUMATOLOGY/KEAA110.037

Background Obesity predisposes to a pro-inflammatory state. Studies have reported worse clinical outcomes in patients with inflammatory arthritis who are obese. The relationship between obesity and outcomes in patients with polymyalgia rheumatica (P... Read More about THE RELATIONSHIP BETWEEN OBESITY AND OUTCOMES IN PATIENTS WITH POLYMYALGIA RHEUMATICA.

O40 Trends in incidence of GCA in the UK (2020)
Journal Article
Barnett, L. A., Helliwell, T., Jordan, K., & Prior, J. (2020). O40 Trends in incidence of GCA in the UK. Rheumatology, 59(Supplement_2), https://doi.org/10.1093/rheumatology/keaa110.039

Background Giant cell arteritis (GCA) is the most common form of medium and large vessel vasculitis. Diagnosis remains difficult since there are a multitude of symptoms experienced by patients with GCA and if not promptly identified or treated, pati... Read More about O40 Trends in incidence of GCA in the UK.

P63 The association between presenting clinical features and subsequent diagnosis of giant cell arteritis (2020)
Journal Article
Barnett, L. A., Helliwell, T., Jordan, K. P., & Prior, J. A. (2020). P63 The association between presenting clinical features and subsequent diagnosis of giant cell arteritis. Rheumatology, 59(Supplement_2), https://doi.org/10.1093/rheumatology/keaa111.062

Background The diagnosis of giant cell arteritis (GCA) remains challenging due to the varied number and type of clinical features (symptoms and comorbidities) that patients with GCA can present with. Prompt diagnosis is important, as if left undiagn... Read More about P63 The association between presenting clinical features and subsequent diagnosis of giant cell arteritis.

The Hospital Frailty Risk Score and its association with in-hospital mortality, cost, length of stay and discharge location in patients with heart failure (2020)
Journal Article
Shing Kwok, C., Zieroth, S., Van Spall, H. G. C., Helliwell, T., Clarson, L., Mohamed, M., …Mamas, M. A. (2020). The Hospital Frailty Risk Score and its association with in-hospital mortality, cost, length of stay and discharge location in patients with heart failure. International Journal of Cardiology, 184-190. https://doi.org/10.1016/j.ijcard.2019.09.064

Background: Little is known about frailty amongst patients hospitalized with heart failure (HF) on a national level. Methods: We conducted a retrospective cohort study of patients admitted to hospital for HF in the United States. We examined how... Read More about The Hospital Frailty Risk Score and its association with in-hospital mortality, cost, length of stay and discharge location in patients with heart failure.

Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study (2019)
Journal Article
Muller, S., Whittle, R., Hider, S. L., Belcher, J., Helliwell, T., Morton, C., …Mallen, C. D. (2020). Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study. Rheumatology, 59(8), 1906-1915. https://doi.org/10.1093/rheumatology/kez533

Objectives. To investigate potential subgroups of primary care diagnosed patients with polymyalgia rheumatica (PMR) based on self-reported pain and stiffness severity over time. Methods. 652 people with an incident PMR diagnosis were recruited fro... Read More about Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study.

Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia (2019)
Journal Article
Jayaweera, K., M Craig, J., M S Zavos, H., Abeysinghe, N., De Alwis, S., Andras, A., …Sumathipala, A. (2019). Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia. BMJ Open, 9(10), Article e029332. https://doi.org/10.1136/bmjopen-2019-029332

INTRODUCTION: Worldwide, 10%-20% of children and adolescents experience mental health conditions. However, most such disorders remain undiagnosed until adolescence or adulthood. Little is known about the factors that influence mental health in childr... Read More about Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia.

Early Unplanned Readmissions after Admission to Hospital with Heart Failure (2019)
Journal Article
Helliwell, T., Clarson, L., Mallen, C., & Mamas, M. (2019). Early Unplanned Readmissions after Admission to Hospital with Heart Failure. American Journal of Cardiology, 736-745. https://doi.org/10.1016/j.amjcard.2019.05.053

Hospital readmissions remain a continued challenge in the care of patients with heart failure (HF). This study aims to examine the rates, temporal trends, predictors and causes of 30-day unplanned readmissions after admission with HF. Patients hospit... Read More about Early Unplanned Readmissions after Admission to Hospital with Heart Failure.

Characteristics of patients with giant cell arteritis who experience visual symptoms (2019)
Journal Article
Shen Chean, C., Prior, J., Helliwell, T., Belcher, J., Mackie, S. L., Hider, S., …Mallen, C. (2019). Characteristics of patients with giant cell arteritis who experience visual symptoms. Rheumatology International, 39, 1789-1796. https://doi.org/10.1007/s00296-019-04422-5

Permanent vision loss is one of the most serious complications of giant cell arteritis (GCA) and therefore prompt diagnosis is paramount. However, diagnosis of GCA remains challenging due to its frequently non-specific presentation. Our aim was to id... Read More about Characteristics of patients with giant cell arteritis who experience visual symptoms.

Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study (2019)
Journal Article
Mallen, Muller, Hider, & Helliwell. (2019). Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study. BMC Medicine, https://doi.org/10.1186/s12916-019-1394-6

Background Antibiotic-induced disturbances of the human microbiota have been implicated in the development of chronic autoimmune conditions. This study aimed to assess whether antibiotic use is associated with the onset of rheumatoid arthritis (RA).... Read More about Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study.

Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey (2019)
Journal Article
Hider, S. L., Muller, S., Helliwell, T., Prior, J. A., Scott, I., Lawton, S. A., …Mallen, C. D. (2019). Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey. Rheumatology, 58(11), 2009-2014. https://doi.org/10.1093/rheumatology/kez184

Objectives: To describe the prevalence of self-reported inflammatory joint symptoms, such as joint pain, stiffness and swelling in UK primary care patients consulting for both musculoskeletal (MSK) and non-musculoskeletal (non-MSK) complaints. Met... Read More about Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey.

216 Characteristics of patients with prevalent giant cell arteritis in UK primary care (2019)
Journal Article
Twomlow, E. L., Prior, J. A., Mackie, S. L., Helliwell, T., Hider, S. L., Belcher, J., …Mallen, C. D. (2019). 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez107.032

Background: Giant cell arteritis (GCA) is a rare, but serious condition affecting older people. Prompt diagnosis remains challenging due to non-specific presentations. Furthermore, there are marked variations in GP referral and management approaches.... Read More about 216 Characteristics of patients with prevalent giant cell arteritis in UK primary care.

E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica (2019)
Journal Article
Morton, C., Muller, S., Hider, S., Belcher, J., Mallen, C. D., & Helliwell, T. (2019). E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica. Rheumatology, 58(Supplement_3), https://doi.org/10.1093/rheumatology/kez110.041

Background: Extended duration of glucocorticoid (GC) therapy can be considered a poor outcome in people with polymyalgia rheumatica (PMR). Being able to predict the likelihood of extended GC therapy at diagnosis would enable earlier specialist referr... Read More about E042 Predicting duration of glucocorticoid therapy in an inception cohort of patients with polymyalgia rheumatica.

Support available for and perceived priorities of people with polymyalgia rheumatica and giant cell arteritis: results of the PMRGCAuk members’ survey 2017 (2018)
Journal Article
Muller, S., O'Brien, A., Helliwell, T., Hay, C. A., Gilbert, K., Mallen, C. D., & Busby, K. (2018). Support available for and perceived priorities of people with polymyalgia rheumatica and giant cell arteritis: results of the PMRGCAuk members’ survey 2017. Clinical Rheumatology, 3411-3418. https://doi.org/10.1007/s10067-018-4220-1

Polymyalgia rheumatica and giant cell arteritis are relatively common, but under research inflammatory rheumatological conditions. This survey aimed to ascertain the matters in which patients feel they need support with these conditions and appraise... Read More about Support available for and perceived priorities of people with polymyalgia rheumatica and giant cell arteritis: results of the PMRGCAuk members’ survey 2017.

Comorbidities in polymyalgia rheumatica: a systematic review (2018)
Journal Article
Partington, R., Helliwell, T., Muller, S., Abdul Sultan, A., & Mallen, C. (2018). Comorbidities in polymyalgia rheumatica: a systematic review. Arthritis Research and Therapy, 258 -?. https://doi.org/10.1186/s13075-018-1757-y

BACKGROUND AND AIM: Comorbidities are known to exist in many rheumatological conditions. Polymyalgia rheumatica (PMR) is a common inflammatory rheumatological condition affecting older people which, prior to effective treatment, causes severe disabil... Read More about Comorbidities in polymyalgia rheumatica: a systematic review.

Challenges of diagnosing and managing polymyalgia rheumatica: a multi-methods study in UK general practice (2018)
Journal Article
Hider, S., Lawton, S., Muller, S., Helliwell, T., Zwierska, I., Mallen, C., & Richardson, J. (2018). Challenges of diagnosing and managing polymyalgia rheumatica: a multi-methods study in UK general practice. British Journal of General Practice (BJGP), 68(676), E783-E793. https://doi.org/10.3399/bjgp18X699557

BACKGROUND: Polymyalgia rheumatica (PMR) is one of the most common inflammatory arthritic disorders seen in older individuals. Most patients with PMR are diagnosed and managed exclusively in general practice, yet primary care-focused research is lack... Read More about Challenges of diagnosing and managing polymyalgia rheumatica: a multi-methods study in UK general practice.