All Outputs (2)

CD4+TGFβ+ cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity, or immunosuppression (2023)
Journal Article
Nazki, S., Reddy, V. R. A. P., Kamble, N., Sadeyen, J.-R., Iqbal, M., Behboudi, S., Shelton, H., & Broadbent, A. J. (in press). CD4+TGFβ+ cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity, or immunosuppression. Frontiers in Immunology, 14, https://doi.org/10.3389/fimmu.2023.1197746

Introduction: Infectious Bursal Disease Virus (IBDV) causes immunosuppression in chickens. While B-cell destruction is the main cause of humoral immunosuppression, bursal T cells from IBDV-infected birds have been reported to inhibit the mitogenic re... Read More about CD4+TGFβ+ cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity, or immunosuppression.

An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells (2023)
Journal Article
Reddy, V. R. A. P., Nazki, S., Asfor, A., & Broadbent, A. J. (2023). An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells. Current Protocols in Neuroscience, 3(1), https://doi.org/10.1002/cpz1.639

Infectious bursal disease virus (IBDV) is a major threat to the productivity of the poultry industry due to morbidity, mortality, and immunosuppression that exacerbates secondary infections and reduces the efficacy of vaccination programs. Field stra... Read More about An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells.