All Outputs (7)

P31 Role of sesquiterpene lactones against human ovarian cancer (2017)
Journal Article

Background: Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency. Using a rat model that recapitulates features of human ESCC,... Read More about P31 Role of sesquiterpene lactones against human ovarian cancer.

Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines (2017)
Presentation / Conference

Ovarian cancer is the second leading cause of death among women in the gynaecological category of cancers. The current post surgery treatment which involves the use of platinum-based therapy with its attendant adverse drug-resistance often results in... Read More about Identification and evaluation of anticancer compounds from three Nigerian plants used in traditional medicines.

Isochondodendrine and 2-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines (2017)
Journal Article

Triclisia subcordata Oliv (Menispermeaceae) is used in herbal medicine for the treatment of cancer and other diseases in Africa. This study aims to isolate minor alkaloids present in this plant and assay their cytotoxic activities. Isochondodendrine... Read More about Isochondodendrine and 2-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines.

Isolation, identification and anti-cancer activity of minor alkaloids from Triclisia subcordata (2017)
Journal Article

No abstract

Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy (2017)
Journal Article

Objectives Non-enzymatic glycation is closely associated with altered mechanical properties of connective tissue. Pregnancy, marked with high levels of female hormones, confers unique alteration to the mechanical properties of pelvic connective tiss... Read More about Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy.

Antibacterial and antibiotic potentiating activities of tropical marine sponge extracts (2017)
Journal Article

Increasing prevalence of antibiotic resistance has led research to focus on discovering new antimicrobial agents derived from the marine biome. Although ample studies have investigated sponges for their bioactive metabolites with promising prospects... Read More about Antibacterial and antibiotic potentiating activities of tropical marine sponge extracts.

A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms (2017)
Journal Article

Ethnopharmacological relevance and aim A decoction of the bark of Cylicodiscus gabunensis Harms is used as a traditional medicine in the treatment of malaria in Nigeria. This study aims to validate the antimalarial potency of this decoction in vitro... Read More about A characterization of the antimalarial activity of the bark of Cylicodiscus gabunensis Harms.