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All Outputs (33)

Automating incidence and prevalence analysis in open cohorts (2024)
Journal Article
Cockburn, N., Hammond, B., Gani, I., Cusworth, S., Acharya, A., Gokhale, K., …Chandan, J. S. (in press). Automating incidence and prevalence analysis in open cohorts. BMC medical research methodology, 24, Article 144. https://doi.org/10.1186/s12874-024-02266-7

Motivation: Data is increasingly used for improvement and research in public health, especially administrative data such as that collected in electronic health records. Patients enter and exit these typically open-cohort datasets non-uniformly; this... Read More about Automating incidence and prevalence analysis in open cohorts.

Endocervical crypt involvement by high-grade cervical intraepithelial neoplasia and its association with high-grade histopathological recurrence after cervical excision in women with negative excision margins: a systematic review and meta-analysis (2023)
Journal Article
Papoutsis, D., Underwood, M., Parry-Smith, W., & Tzavara, C. (2024). Endocervical crypt involvement by high-grade cervical intraepithelial neoplasia and its association with high-grade histopathological recurrence after cervical excision in women with negative excision margins: a systematic review and meta-analysis. Archives of Gynecology and Obstetrics, 309, 939–948. https://doi.org/10.1007/s00404-023-07242-y

Background There is a growing body of evidence suggesting that endocervical crypt involvement by high-grade cervical intraepithelial neoplasia (CIN) may represent a risk factor for disease recurrence after cervical treatment. Objectives To provi... Read More about Endocervical crypt involvement by high-grade cervical intraepithelial neoplasia and its association with high-grade histopathological recurrence after cervical excision in women with negative excision margins: a systematic review and meta-analysis.

The association between menstrual cycle characteristics and cardiometabolic outcomes in later life: a retrospective matched cohort study of 704,743 women from the UK. (2023)
Journal Article
Okoth, K., Parry-Smith, W., Thomas, G. N., Nirantharakumar, K., & Adderley, N. J. (2023). The association between menstrual cycle characteristics and cardiometabolic outcomes in later life: a retrospective matched cohort study of 704,743 women from the UK. BMC Medicine, 21, Article 104. https://doi.org/10.1186/s12916-023-02794-x

Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study. (2022)
Journal Article
Fotopoulou, C., Khan, T., Bracinik, J., Glasbey, J., Abu-Rustum, N., Chiva, L., …Parry-Smith, W. (2022). Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study. American Journal of Obstetrics and Gynecology, 227(5), 735.e1-735.e25. https://doi.org/10.1016/j.ajog.2022.06.052

Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK (2022)
Journal Article
Rimmer, M. P., Henderson, I., Parry-Smith, W., Raglan, O., Tamblyn, J., Heazell, A. E. P., …working group, T. U. N. (2023). Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK. International Journal of Epidemiology, 52(1), 295–308. https://doi.org/10.1093/ije/dyac100

Background The Medical Certificate of Stillbirth (MCS) records data about a baby’s death after 24 weeks of gestation but before birth. Major errors that could alter interpretation of the MCS were widespread in two UK-based regional studies. Metho... Read More about Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK.

Effectiveness of a web-based virtual journal club to promote medical education (Web-Ed): protocol of a multicentre pragmatic randomised trial (2022)
Journal Article
Rimmer, M., Elfaki, N., Dunlop, C., Coleburt, D., Cowan, N., Raglan, O., …Al Wattar, B. (2022). Effectiveness of a web-based virtual journal club to promote medical education (Web-Ed): protocol of a multicentre pragmatic randomised trial. BMJ Open, 12(6), Article e058610. https://doi.org/10.1136/bmjopen-2021-058610

Introduction A journal club (JC) is a commonly used medical educational tool. Videoconferencing technology can facilitate the delivery of JCs, however, there remains no evidence on the role of web-based virtual JCs in promoting the acquisition and re... Read More about Effectiveness of a web-based virtual journal club to promote medical education (Web-Ed): protocol of a multicentre pragmatic randomised trial.

Healing pattern of the cervical stroma following cold coagulation treatment for cervical intraepithelial neoplasia: A case report (2022)
Journal Article
Papoutsis, D., Williams, J., Underwood, M., & Parry-Smith, W. (2022). Healing pattern of the cervical stroma following cold coagulation treatment for cervical intraepithelial neoplasia: A case report. Oncology Letters, 23, Article 81. https://doi.org/10.3892/ol.2022.13201

Cold coagulation of the cervix for cervical intraepithelial neoplasia (CIN), when compared with cervical excision, has previously demonstrated comparable cure rates and a reduction in the rate of spontaneous preterm birth. In the present report the h... Read More about Healing pattern of the cervical stroma following cold coagulation treatment for cervical intraepithelial neoplasia: A case report.

Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study (2021)
Journal Article
Collaborative*, C., & Parry-Smith, W. (2021). Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study. Lancet Oncology, 22(11), 1507-1517. https://doi.org/10.1016/S1470-2045%2821%2900493-9

Background Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery d... Read More about Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.

SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. (2021)
Journal Article
Collaborative, C., Collaborative, G., & Parry-Smith, W. (2022). SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia, 77(1), 28-39. https://doi.org/10.1111/anae.15563

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patien... Read More about SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study..

Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. (2021)
Journal Article
Collaborative, C., Collaborative, G., & Parry-Smith, W. (2021). Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia, 76(11), 1454-1464. https://doi.org/10.1111/anae.15560

We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing el... Read More about Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study..

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study (2021)
Journal Article
Collaborative, C., Collaborative, G., & Parry-Smith, W. (2021). SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. British Journal of Surgery, 108(9), 1056-1063. https://doi.org/10.1093/bjs/znab101

Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV... Read More about SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

Postpartum haemorrhage and risk of mental ill health: A population-based longitudinal study using linked primary and secondary care databases (2021)
Journal Article
Parry-Smith, W., Okoth, K., Subramanian, A., Gokhale, K. M., Chandan, J. S., Humpston, C., …Šumilo, D. (2021). Postpartum haemorrhage and risk of mental ill health: A population-based longitudinal study using linked primary and secondary care databases. Journal of Psychiatric Research, 137, 419-425. https://doi.org/10.1016/j.jpsychires.2021.03.022

The FAST‐M complex intervention for the detection and management of maternal sepsis in low‐resource settings: a multi‐site evaluation (2021)
Journal Article
Cheshire, J., Jones, L., Munthali, L., Kamphinga, C., Liyaya, H., Phiri, T., …Lissauer, D. (2021). The FAST‐M complex intervention for the detection and management of maternal sepsis in low‐resource settings: a multi‐site evaluation. BJOG: An International Journal of Obstetrics and Gynaecology, 128(8), 1324–1333. https://doi.org/10.1111/1471-0528.16658

Objective To evaluate whether the implementation of the FAST-M complex intervention was feasible and improved the recognition and management of maternal sepsis in a low-resource setting. Design A before-and-after design. Setting Fifteen gove... Read More about The FAST‐M complex intervention for the detection and management of maternal sepsis in low‐resource settings: a multi‐site evaluation.

Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units (2020)
Journal Article
Cheshire, J., Lissauer, D., Parry-Smith, W., Tobias, A., Smith, G. B., Isaacs, R., & Hundley, V. (in press). Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units. Resuscitation Plus, 5, Article 100060. https://doi.org/10.1016/j.resplu.2020.100060

Background The use of obstetric early warning systems (OEWS) are recommended as an adjunct to reduce maternal morbidity and mortality. The aim of this review was to document the variation in OEWS trigger thresholds and the quality of information inc... Read More about Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units.

Expansile Endocervical Crypt Involvement by CIN2 – 3 as a Risk Factor for High Grade Cytology Recurrence After Cold Coagulation Cervical Treatment (2020)
Journal Article
Papoutsis, D., Underwood, M., Williams, J., Parry-Smith, W., & Panikkar, J. (in press). Expansile Endocervical Crypt Involvement by CIN2 – 3 as a Risk Factor for High Grade Cytology Recurrence After Cold Coagulation Cervical Treatment. Geburtshilfe und Frauenheilkunde, 80(9), 941-948. https://doi.org/10.1055/a-1202-2157

Introduction To determine whether expansile endocervical crypt involvement (ECI) on pretreatment cervical punch biopsies is a risk factor for high grade cytology recurrence in women following cold coagulation for cervical intraepithelial neoplasia (C... Read More about Expansile Endocervical Crypt Involvement by CIN2 – 3 as a Risk Factor for High Grade Cytology Recurrence After Cold Coagulation Cervical Treatment.

Babies in occiput posterior position are significantly more likely to require an emergency cesarean birth compared with babies in occiput transverse position in the second stage of labor: A prospective observational study. (2019)
Journal Article
Tempest, N., Lane, S., Hapangama, D., Collaborative in Obstetrics, U. A. R. T., (UK-ARCOG), G., & Parry-Smith, W. (2020). Babies in occiput posterior position are significantly more likely to require an emergency cesarean birth compared with babies in occiput transverse position in the second stage of labor: A prospective observational study. Acta obstetricia et gynecologica Scandinavica, 99(4), 537-545. https://doi.org/10.1111/aogs.13765

Introduction Malposition complicates 2-13% of births at delivery, leading to increased obstetric interventions (cesarean section and instrumental delivery) and higher rates of adverse fetal and maternal outcomes. Limited data are available regarding... Read More about Babies in occiput posterior position are significantly more likely to require an emergency cesarean birth compared with babies in occiput transverse position in the second stage of labor: A prospective observational study..

Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes: A UK multicentre observational study. (2019)
Journal Article
Al Wattar, B. H., Lakhiani, A., Sacco, A., Siddharth, A., Bain, A., Calvia, A., …study group, A. (2019). Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes: A UK multicentre observational study. European Journal of Obstetrics and Gynecology and Reproductive Biology, 240, 62-67. https://doi.org/10.1016/j.ejogrb.2019.06.012

Objective To evaluate the value of fetal scalp blood sampling (FBS) as an adjunct test to cardiotocography, to predict adverse neonatal outcomes. Study design A multicentre service evaluation observational study in forty-four maternity units in... Read More about Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes: A UK multicentre observational study..

Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study (2018)
Journal Article
Papoutsis, D., Underwood, M., Parry-Smith, W., & Panikkar, J. (2018). Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study. Archives of Gynecology and Obstetrics, 297(4), 1015-1025. https://doi.org/10.1007/s00404-018-4704-x

Purpose To compare the pregnancy outcomes between women who were treated with cold-coagulation versus large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia. Methods This was a retrospective cohort study of... Read More about Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study.