All Outputs (10)

Current State-of-the-Art 3D Tissue Models and Their Compatibility with Live Cell Imaging (2017)
Book Chapter
Bardsley, K., Deegan, A. J., El Haj, A., & Yang, Y. (2017). Current State-of-the-Art 3D Tissue Models and Their Compatibility with Live Cell Imaging. In Multi-Parametric Live Cell Microscopy of 3D Tissue Models (3-18). (1). Springer. https://doi.org/10.1007/978-3-319-67358-5_1

Mammalian cells grow within a complex three-dimensional (3D) microenvironment where multiple cells are organized and surrounded by extracellular matrix (ECM). The quantity and types of ECM components, alongside cell-to-cell and cell-to-matrix interac... Read More about Current State-of-the-Art 3D Tissue Models and Their Compatibility with Live Cell Imaging.

Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy (2017)
Journal Article
Yang. (2017). Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy. Medical Hypotheses, https://doi.org/10.1016/j.mehy.2017.09.016

Abstract A few studies have revealed that the advanced glycation content of the vaginal wall in pelvic organ prolapse tissues is elevated. This elevation makes advanced glycation a significant association with the disease. Early detection of vaginal... Read More about Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy.

Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production. (2017)
Journal Article
Yang. (2017). Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production. Histochemistry and Cell Biology, 625-638. https://doi.org/10.1007/s00418-017-1602-4

Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The PCM is rich in hyaluronan, proteoglycans, and collagen II, and it is the exclusive location of collagen VI in articular cartilage. Collagen VI anchors... Read More about Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production..

Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production (2017)
Journal Article
Yang. (2017). Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production. Histochemistry and Cell Biology, 625-638. https://doi.org/10.1007/s00418-017-1602-4

Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The PCM is rich in hyaluronan, proteoglycans, and collagen II, and it is the exclusive location of collagen VI in articular cartilage. Collagen VI anchors... Read More about Co-culture of chondrons and mesenchymal stromal cells reduces the loss of collagen VI and improves extracellular matrix production.

Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering (2017)
Journal Article
Law, J. X., Liau, L. L., Saim, A., Yang, Y., & Idrus, R. (2017). Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering. Tissue Engineering and Regenerative Medicine, 14(6), 699-718. https://doi.org/10.1007/s13770-017-0075-9

Electrospinning is a simple and versatile technique to fabricate continuous fibers with diameter ranging from micrometers to a few nanometers. To date, the number of polymers that have been electrospun has exceeded 200. In recent years, electrospinni... Read More about Electrospun Collagen Nanofibers and Their Applications in Skin Tissue Engineering.

Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy (2017)
Journal Article
Weli, H. K., Akhtar, R., Chang, Z., Li, W., Cooper, J., & Yang, Y. (2017). Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 78-85. https://doi.org/10.1016/j.ejogrb.2017.04.037

Objectives Non-enzymatic glycation is closely associated with altered mechanical properties of connective tissue. Pregnancy, marked with high levels of female hormones, confers unique alteration to the mechanical properties of pelvic connective tiss... Read More about Advanced glycation products' levels and mechanical properties of vaginal tissue in pregnancy.

Erratum to: Methods for evaluating medical tests and biomarkers (2017)
Journal Article
Gopalakrishna, G., Investigators, S. C., Langendam, M., Scholten, R., Bossuyt, P., Leeflang, M., …Yang, Y. (2017). Erratum to: Methods for evaluating medical tests and biomarkers. Diagnostic and Prognostic Research, 1(1), https://doi.org/10.1186/s41512-017-0011-4

The original MEMTAB Abstracts in Diagnostic and Prognostic Research contains the incorrect year on individual abstracts in the PDF [1]. “Diagnostic and Prognostic Research 2016” under the correspondence line should therefore have been written as “... Read More about Erratum to: Methods for evaluating medical tests and biomarkers.

Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition. (2017)
Journal Article
Yang, Y. (2017). Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition. Tissue Engineering Part C: Methods, 228 - 236. https://doi.org/10.1089/ten.TEC.2017.0008

Extracellular matrix (ECM) is an essential component of tissues and provides both integrity and biological cues for cells. Collagen is one of the major proteins found within the ECM and therefore is an essential component of all engineered tissues. T... Read More about Fluorescent Labeling of Collagen Production by Cells for Noninvasive Imaging of Extracellular Matrix Deposition..

Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy (2017)
Journal Article
Gillies, D., Gamal, W., Downes, A., Reinwald, Y., Yang, Y., El Haj, A., & Bagnaninchi, P. O. (2017). Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy. Proceedings of SPIE, https://doi.org/10.1117/12.2251492

There is an unmet need in tissue engineering for non-invasive, label-free monitoring of cell mechanical behaviour in their physiological environment. Here, we describe a novel optical coherence phase microscopy (OCPM) set-up which can map relative... Read More about Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy.

Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation (2017)
Journal Article
Yang, Y. (2017). Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation. Frontiers in Bioengineering and Biotechnology, 1-11. https://doi.org/10.3389/fbioe.2017.00006

Scaffolds for regenerative medicine applications should instruct cells with the appropriate signals, including biophysical stimuli such as stress and strain, to form the desired tissue. Apart from that, scaffolds, especially for load-bearing applicat... Read More about Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation.