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A microscopic and macroscopic study of aging collagen on its molecular structure, mechanical properties, and cellular response (2013)
Journal Article
Wilson, S. L., Guilbert, M., Sulé‐Suso, J., Torbet, J., Jeannesson, P., Sockalingum, G. D., & Yang, Y. (2014). A microscopic and macroscopic study of aging collagen on its molecular structure, mechanical properties, and cellular response. FASEB Journal, 28(1), 14-25. https://doi.org/10.1096/fj.13-227579

During aging, collagen structure changes, detrimentally affecting tissues' biophysical and biomechanical properties due to an accumulation of advanced glycation end-products (AGEs). In this investigation, we conducted a parallel study of microscopic... Read More about A microscopic and macroscopic study of aging collagen on its molecular structure, mechanical properties, and cellular response.

Corneal Stromal Cell Plasticity: In Vitro Regulation of Cell Phenotype Through Cell-Cell Interactions in a Three-Dimensional Model (2013)
Journal Article
Wilson, S. L., Yang, Y., & El Haj, A. J. (2014). Corneal Stromal Cell Plasticity: In Vitro Regulation of Cell Phenotype Through Cell-Cell Interactions in a Three-Dimensional Model. Tissue engineering. Part A, 20(1-2), 225-238. https://doi.org/10.1089/ten.tea.2013.0167

In vivo, epithelial cells are connected both anatomically and functionally with stromal keratocytes. Co-culturing aims at recapturing this cellular anatomy and functionality by bringing together two or more cell types within the same culture environm... Read More about Corneal Stromal Cell Plasticity: In Vitro Regulation of Cell Phenotype Through Cell-Cell Interactions in a Three-Dimensional Model.

Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation (2013)
Journal Article
Pijanka, J. K., Stone, N., Rutter, A. V., Forsyth, N., Sockalingum, G. D., Yang, Y., & Sulé-Suso, J. (2013). Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation. Analyst, 138(17), 5052. https://doi.org/10.1039/c3an00968h

Raman spectroscopy has been widely used to study its possible clinical application in cancer diagnosis. However, in order to make it into clinical practice, it is important that this technique is able not only to identify cancer cells from their norm... Read More about Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation.

Optical Coherence Tomography to delineate the interactions of PAMAM dendrimers with the porcine skin surface (2013)
Journal Article
Judd, A. M., Moss, G. P., Heylings, J., Wan, K., & Yang, Y. (2013). Optical Coherence Tomography to delineate the interactions of PAMAM dendrimers with the porcine skin surface. Proceedings of SPIE, 8580, Article ARTN 85800G. https://doi.org/10.1117/12.2004754

Polyamidoamine (PAMAM) dendrimers have been topically applied to the skin and utilised as a permeation enhancer for a range of therapeutic compounds. However, very little is known about the mechanism of enhancement. This study used optical coherence... Read More about Optical Coherence Tomography to delineate the interactions of PAMAM dendrimers with the porcine skin surface.

Errata: Study of optical properties and proteoglycan content of tendons by polarization sensitive optical coherence tomography (2013)
Journal Article
Yang, Y., Rupani, A., Bagnaninchi, P., Wimpenny, I., & Weightman, A. (2013). Errata: Study of optical properties and proteoglycan content of tendons by polarization sensitive optical coherence tomography. Journal of Biomedical Optics, 18(1), 019801. https://doi.org/10.1117/1.JBO.18.1.019801

This article [J. Biomed. Opt.. 17, (8 ), 081417 (2012)] was originally published online on 2 August 2012 with an error in the reference citation of Fig. 1. The correct figure caption and references for Fig. 1 are shown below. A new reference was adde... Read More about Errata: Study of optical properties and proteoglycan content of tendons by polarization sensitive optical coherence tomography.

Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model (2012)
Journal Article
Rutter, A. V., Chippendale, T. W. E., Yang, Y., Španěl, P., Smith, D., & Sulé-Suso, J. (in press). Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model. Analyst, 138(1), 91-95. https://doi.org/10.1039/c2an36185j

Our previous studies have shown that both lung cancer cells and non-malignant lung cells release acetaldehyde in vitro. However, data from other laboratories have produced conflicting results. Furthermore, all these studies have been carried out in 2... Read More about Quantification by SIFT-MS of acetaldehyde released by lung cells in a 3D model.