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All Outputs (114)

Physiotherapy for the Management of Polymyalgia Rheumatica: Results From a UK Cross‐Sectional Survey (2025)
Journal Article
O'Brien, A. V., Muller, S., Liddle, J., Thomas, M. J., & Mallen, C. D. (2025). Physiotherapy for the Management of Polymyalgia Rheumatica: Results From a UK Cross‐Sectional Survey. Musculoskeletal Care, 23(3), Article e70155. https://doi.org/10.1002/msc.70155

Introduction: Polymyalgia rheumatica (PMR) international management guidelines advocate patient education and individualised exercises but lack evidence and physiotherapy practice for PMR is unknown. PMR is typically treated with glucocorticoids, but... Read More about Physiotherapy for the Management of Polymyalgia Rheumatica: Results From a UK Cross‐Sectional Survey.

Trends in the use of video consultation in general practice during COVID-19: impact of practice and country characteristics based on the international, cross-sectional PRICOV-19 study (2025)
Journal Article
Kirk, U. B., Pellin, M. D. L. C. G., Hoffmann, K., Stummer, F. O., Van Poel, E., Vestergaard, C. H., Holm, A., Tatsioni, A., Petrazzuoli, F., Neves, A. L., Bravo, R. G., Asenova, R., Mallen, C., Bojaj, G., Rochfort, A., Bussche, P. V., Collins, C., Willems, S., Bro, F., Rohrbasser, A., & Huibers, L. (2025). Trends in the use of video consultation in general practice during COVID-19: impact of practice and country characteristics based on the international, cross-sectional PRICOV-19 study. BMC Primary Care, 26(1), 13. https://doi.org/10.1186/s12875-025-02892-0

Background: The COVID-19 pandemic accelerated the use of telemedicine, specifically video consultations as they provide healthcare access in challenging situations where face-to-face encounters are not possible. Nevertheless, it remains largely unkno... Read More about Trends in the use of video consultation in general practice during COVID-19: impact of practice and country characteristics based on the international, cross-sectional PRICOV-19 study.

392 Sterile Water Injections for Acute Pain Relief in Renal Colic: A Meta-Analysis of Randomised Controlled Trials (2025)
Presentation / Conference Contribution
Perros, I., Swift, C., Mallen, C., Sokhal, B. S., & Kitchen, M. (2025, March). 392 Sterile Water Injections for Acute Pain Relief in Renal Colic: A Meta-Analysis of Randomised Controlled Trials. Poster presented at ASiT Surgical Conference, Belfast, UK

Aim
Effective renal colic management relies on optimal pain relief. Each medication has its distinct side effects and contraindications. Sterile water injections (SWIs) have emerged as a potential alternative to standard treatment. This systematic r... Read More about 392 Sterile Water Injections for Acute Pain Relief in Renal Colic: A Meta-Analysis of Randomised Controlled Trials.

Process and feasibility of implementing guideline recommendations for the care of osteoarthritis in West Africa (2025)
Journal Article
Babatunde, O. O., Adetunji, O., Alonge, I., Owoyemi, T., Ayinmode, E., Ogunbanjo, A., White, S., Adebajo, A., Mallen, C., & Dziedzic, K. (2025). Process and feasibility of implementing guideline recommendations for the care of osteoarthritis in West Africa. BMJ Global Health, 10(6), Article e018714. https://doi.org/10.1136/bmjgh-2024-018714

To assess the feasibility of a guideline-informed model of care for osteoarthritis in primary healthcare and community pharmacy settings in the West African context. The 4-phase mixed-methods programme of research undertaken in Southwest Nigeria, Wes... Read More about Process and feasibility of implementing guideline recommendations for the care of osteoarthritis in West Africa.

Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial (2025)
Other
Thomas, M. J., Hughes, G., Cooke, K., Butler-Walley, S., Marshall, E., Bowyer, L., Wathall, S., Smith, J., Lawton, S. A., Brammar, J., Burnett, T., Drake, C., Foster, N. E., Hendry, G. J., Holden, M. A., Jaki, T., Joseph, R., Keenan, A.-M., Kigozi, J., Lewis, M., …Roddy, E. (2025). Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial

Plantar heel pain (PHP) is the most common soft tissue foot condition and impairs mobility, physical function, ability to work, and quality of life. Systematic reviews highlight a need for high-quality randomised controlled trials (RCTs) of exercises... Read More about Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial.

Prostate microcalcification crystallography as a marker of pathology (2025)
Journal Article
Gosling, S. B., Arnold, E. L., Adams, L., Cool, P., Geraki, K., Kitchen, M. O., Lyburn, I. D., Rogers, K. D., Snow, T., Stone, N., & Greenwood, C. E. (2025). Prostate microcalcification crystallography as a marker of pathology. Scientific Reports, 15(1), Article 14979. https://doi.org/10.1038/s41598-025-98692-8

Prostate cancer remains the most common male cancer; however, treatment regimens remain unclear in some cases due to a lack of agreement in current testing methods. Therefore, there is an increasing need to identify novel biomarkers to better counsel... Read More about Prostate microcalcification crystallography as a marker of pathology.

P055 Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case-control study in the Clinical Practice Research Datalink Aurum (2025)
Presentation / Conference Contribution
Scott, I. C., Daud, N., Bailey, J., Twohig, H., Hider, S., Mallen, C. D., Jordan, K. P., & Muller, S. (2025, April). P055 Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case-control study in the Clinical Practice Research Datalink Aurum. Poster presented at British Society for Rheumatology Annual Conference 2025, Manchester Central Convention Complex, Manchester, England, UK

Background/Aims Gabapentinoids are increasingly prescribed in inflammatory arthritis (IA), despite no trial evidence for efficacy at managing pain in this population. Observational studies in non-IA populations suggest gabapentinoids are associated w... Read More about P055 Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case-control study in the Clinical Practice Research Datalink Aurum.

P102 Pain management and its variation by deprivation in patients with inflammatory arthritis: the PAIN PATH survey (2025)
Presentation / Conference Contribution
Scott, I. C., Daud, N., Hider, S., Paskins, Z., Twohig, H., Halliday, N., Mallen, C. D., Jordan, K. P., & Muller, S. (2025, April). P102 Pain management and its variation by deprivation in patients with inflammatory arthritis: the PAIN PATH survey. Poster presented at British Society for Rheumatology Annual Conference 2025, Manchester Central Convention Complex, Manchester, England, UK

Background/Aims UK-based electronic health record studies show that many patients with inflammatory arthritis (IA) receive opioid and gabapentinoid prescriptions - particularly in areas of deprivation - despite little and no evidence for efficacy, re... Read More about P102 Pain management and its variation by deprivation in patients with inflammatory arthritis: the PAIN PATH survey.

Proactive clinical review of patients taking opioid medicines long term for persistent pain led by clinical pharmacists in primary care teams (PROMPPT): a non-randomised mixed methods feasibility study (2025)
Journal Article
Ashworth, J., Cornwall, N., Harrisson, S., Woodcock, C., Nicholls, E., Lancaster, G., Wathall, S., Laing, L., Helliwell, T., Jowett, S., Kigozi, J., Mallen, C., Avery, A., Knaggs, R., Pincus, T., White, S., & Jinks, C. (2025). Proactive clinical review of patients taking opioid medicines long term for persistent pain led by clinical pharmacists in primary care teams (PROMPPT): a non-randomised mixed methods feasibility study. Pilot and Feasibility Studies, 11(1), Article 53. https://doi.org/10.1186/s40814-025-01636-2

Background: Given the poor long-term effectiveness of opioids for persistent non-cancer pain, and their potential for harm, evidence-based interventions to address opioid overprescribing for persistent pain are needed. This study aimed to explore the... Read More about Proactive clinical review of patients taking opioid medicines long term for persistent pain led by clinical pharmacists in primary care teams (PROMPPT): a non-randomised mixed methods feasibility study.

Pragmatic Evaluation of an Improvement Program for People Living With Modifiable High-Risk COPD Versus Usual Care: Protocols for the Cluster Randomized PREVAIL Trial. (2025)
Journal Article
Hickman, K., Tarabichi, Y., Dickens, A. P., Pullen, R., Kerr, M., Couper, A., Evans, A., Gatenby, J., Alves, L., Ariti, C., Bafadhel, M., Carter, V., Chalmers, J., Chen, R., Devereux, G., Drummond, M. B., Gibson, J. M., Halpin, D. M. G., Han, M., Hanania, N. A., …Price, D. (2025). Pragmatic Evaluation of an Improvement Program for People Living With Modifiable High-Risk COPD Versus Usual Care: Protocols for the Cluster Randomized PREVAIL Trial. COPD: Journal of Chronic Obstructive Pulmonary Disease, https://doi.org/10.15326/jcopdf.2024.0564

The burden of COPD is well established, but opportunities for earlier diagnosis and improved management are still missed. Compared to the general COPD population, patients with a history of exacerbations and sub-optimal treatment ('modifiable high-ri... Read More about Pragmatic Evaluation of an Improvement Program for People Living With Modifiable High-Risk COPD Versus Usual Care: Protocols for the Cluster Randomized PREVAIL Trial..

254 CO-DESIGNING AN OA BOOKLET FOR AOTEAROA NEW ZEALAND (2025)
Presentation / Conference Contribution
O'Brien, D., Francis, B., Griffin, D., Campbell, L., Khoo, C., & Nakarada-Kordic, I. (2025, April). 254 CO-DESIGNING AN OA BOOKLET FOR AOTEAROA NEW ZEALAND. Presented at 2025 OARSI World Congress on Osteoarthritis, Incheon, South Korea

001 PSYCHOLOGICAL AND PAIN RELATED COMORBIDITIES IN PEOPLE WITH OSTEOARTHRITIS IN EUROPE - EVIDENCE FROM THE ComOA STUDY (2025)
Presentation / Conference Contribution
Swain, S., Coupland, C., Thompson, W., Mallen, C., Alhambra, D. P., Englund, M., Bierma-Zeinstra, S., Doherty, M., & Zhang, W. (2025, April). 001 PSYCHOLOGICAL AND PAIN RELATED COMORBIDITIES IN PEOPLE WITH OSTEOARTHRITIS IN EUROPE - EVIDENCE FROM THE ComOA STUDY. Presented at 2025 OARSI World Congress on Osteoarthritis, Incheon, South Korea

Clinical and cost-effectiveness of communication skills e-learning for primary care practitioners on patients' musculoskeletal pain and enablement: the Talking in Primary care (TIP) cluster-randomised controlled trial (2025)
Preprint / Working Paper
Bishop, F. L., Becque, T., Garfield, K., Cross, N., Dewar-Haggart, R., Teasdale, E., Herbert, A., Robinson, M. E., Ridd, M. J., Mallen, C., Clarson, L., Bostock, J., Stuart, B., Morrison, L., Pollet, S., Vennik, J., Atherton, H., Howick, J., Leydon, G. M., Nuttall, J., …Everitt, H. A. (2025). Clinical and cost-effectiveness of communication skills e-learning for primary care practitioners on patients' musculoskeletal pain and enablement: the Talking in Primary care (TIP) cluster-randomised controlled trial

Objectives To determine the effectiveness and cost-effectiveness of a brief communication skills e-learning package on empathy and optimism for practitioners consulting with adult primary care patients presenting with musculoskeletal (MSK) pain.

D... Read More about Clinical and cost-effectiveness of communication skills e-learning for primary care practitioners on patients' musculoskeletal pain and enablement: the Talking in Primary care (TIP) cluster-randomised controlled trial.

300 Co-creating a weight management programme addressing patient reported barriers and enablers for weight loss. pilot study and service evaluation (2025)
Presentation / Conference Contribution
Hadley-Barrows, T., Jassall, J., Johnson, A., Singh Chugger, N., Smith, C., Moore, J., Olomolaiye, B., Stone, A., Parker, L., Jones, S., & Kaur Bassi, J. (2024, October). 300 Co-creating a weight management programme addressing patient reported barriers and enablers for weight loss. pilot study and service evaluation. Poster presented at CSP Annual Conference 2024, UK

Purpose: Osteoarthritis is the most common form of arthritis and its prevalence is increasing. It is more common in women, people living in deprived areas, people aged 45 and over and people living with obesity.
NHS estimates suggest that currently... Read More about 300 Co-creating a weight management programme addressing patient reported barriers and enablers for weight loss. pilot study and service evaluation.

A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol (2024)
Journal Article
Bullock, L., Nicholls, E., Cherrington, A., Butler-Walley, S., Clark, E. M., Fleming, J., Leyland, S., Bentley, I., Thomas, S., Iglesias-Urrutia, C. P., Webb, D., Smith, J., Bathers, S., Lewis, S., Clifford, A., Siciliano, M., Protheroe, J., Ryan, S., Lefroy, J., Dale, N., …Paskins, Z. (2024). A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol. NIHR Open Research, https://doi.org/10.3310/nihropenres.13571.2

Background
Good quality shared decision-making (SDM) conversations involve people with, or at risk of osteoporosis and clinicians collaborating to decide, where appropriate, which evidence-based medicines best fit the person’s life, beliefs, and val... Read More about A person-centred consultation intervention to improve shared decision-making about, and uptake of, osteoporosis medicines (iFraP): a pragmatic, parallel-group, individual randomised controlled trial protocol.

Proactive clinical Review of patients taking Opioid Medicines long-term for persistent Pain led by clinical Pharmacists in primary care Teams (PROMPPT). A non-randomised Mixed Methods Feasibility Study. (2024)
Preprint / Working Paper
Ashworth, J., Cornwall, N., Harrisson, S. A., Woodcock, C., Nicholls, E., Lancaster, G., Wathall, S., Laing, L., Helliwell, T., Jowett, S., Kigozi, J., Mallen, C. D., Avery, A., Knaggs, R., Pincus, T., White, S., & Jinks, C. (2024). Proactive clinical Review of patients taking Opioid Medicines long-term for persistent Pain led by clinical Pharmacists in primary care Teams (PROMPPT). A non-randomised Mixed Methods Feasibility Study

Background:

Given the poor long-term effectiveness of opioids for persistent non-cancer pain, and their potential for harm, evidence–based interventions to address opioid overprescribing for persistent pain are needed. This study aimed to explore... Read More about Proactive clinical Review of patients taking Opioid Medicines long-term for persistent Pain led by clinical Pharmacists in primary care Teams (PROMPPT). A non-randomised Mixed Methods Feasibility Study..

Feasibility trial of a new digital training package to enhance primary care practitioners’ communication of clinical empathy and realistic optimism (2024)
Preprint / Working Paper
L Bishop, F., Howick, J., Vennik, J., Bostock, J., Little, P., Mallen, C., Morrison, L., Steele, M., Stuart, B., Hughes, S., Smith, K., Ratnapalan, M., Lyness, E., Dambha-Miller, H., Tiwari, R., Lockyer-Stevens, C., & Everitt, H. Feasibility trial of a new digital training package to enhance primary care practitioners’ communication of clinical empathy and realistic optimism

Evaluating qualitative data analysis workshops from the perspective of public contributors (2024)
Journal Article
Moult, A., McGrath, C., Lippiett, K., Coope, C., Turner, A., Chillcott, S., Parton, L., Holloway, P., Dace, S., Gibson, A., Jinks, C., Paskins, Z., Portillo, M. C., Mann, C., & Dziedzic, K. (2024). Evaluating qualitative data analysis workshops from the perspective of public contributors. Research Involvement and Engagement, 10(1), Article 99. https://doi.org/10.1186/s40900-024-00628-5

Background: The aim of this project is to evaluate public contributors’ experiences of their involvement in qualitative data analysis workshops during an on-going research project titled ‘Personalised Primary care for Patients with Multiple long-term... Read More about Evaluating qualitative data analysis workshops from the perspective of public contributors.