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All Outputs (4)

Structural characterisation of the human innate immune proteins FIBCD1 and surfactant proteins A and D (2021)
Thesis
Williams, H. M. (2021). Structural characterisation of the human innate immune proteins FIBCD1 and surfactant proteins A and D. (Thesis). Keele University

The surfactant proteins A and D (SP-A and SP-D) and fibrinogen C containing domain 1 (FIBCD1) are pattern recognition receptors, which recognise pathogens through the binding of carbohydrate residues embedded within surface structures. The work prese... Read More about Structural characterisation of the human innate immune proteins FIBCD1 and surfactant proteins A and D.

Structural characterisation of human immunoglobulin G Fc fragment and its interaction with heparin (2020)
Thesis
Earps, H. F. (2020). Structural characterisation of human immunoglobulin G Fc fragment and its interaction with heparin. (Thesis). Keele University

Human immunoglobulin (Ig) G is the most commonly found class of antibody in the human body and is involved in pathogen recognition as a part of the adaptive and innate immune response. Recognition occurs through the fragment antibody binding (FAB) re... Read More about Structural characterisation of human immunoglobulin G Fc fragment and its interaction with heparin.

Investigation of modified forms of serum C-reactive protein in diabetes mellitus (2019)
Thesis
Mahmood, S. M. (2019). Investigation of modified forms of serum C-reactive protein in diabetes mellitus. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414936

C-reactive protein (CRP) is known to dissociate to its monomeric subunits (mCRP) in vivo. Furthermore, hyperglycaemia associated with diabetes mellitus (DM) results in glycation of serum proteins to a various extent based on their half-life and glyca... Read More about Investigation of modified forms of serum C-reactive protein in diabetes mellitus.