All Outputs (3)

Pharmacological analysis of dopaminergic synaptic plasticity in rodent lateral entorhinal cortex (2021)
Thesis
Pettitt, G. (2021). Pharmacological analysis of dopaminergic synaptic plasticity in rodent lateral entorhinal cortex. (Thesis). Keele University

Despite receiving the second largest dopaminergic projection from the ventral tegmental area (VTA) and having a pivotal role in conveying non-spatial information received from sensory cortices, the physiological functions of the lateral entorhinal co... Read More about Pharmacological analysis of dopaminergic synaptic plasticity in rodent lateral entorhinal cortex.

The role of ATP6V1E1 in the control of apoptosis, survival and motility of breast cancer cells (2020)
Thesis
Mohammed, S. N. (2020). The role of ATP6V1E1 in the control of apoptosis, survival and motility of breast cancer cells. (Thesis). Keele University

Background and aims: Aggressiveness and invasiveness of breast cancer are influenced by multiple cellular and molecular factors, some of which are yet to be elucidated. In normal cells, vacuolar H (+) -ATPase (V ATPases), which pump protons across th... Read More about The role of ATP6V1E1 in the control of apoptosis, survival and motility of breast cancer cells.

Evaluation of cultured cochlear fibrocytes as a cell replacement therapy: comparison with native fibrocytes (2020)
Thesis
Osborn, A. H. (2020). Evaluation of cultured cochlear fibrocytes as a cell replacement therapy: comparison with native fibrocytes. (Thesis). Keele University

Fibrocyte degeneration in the cochlear lateral wall is one possible pathology of age-related metabolic hearing loss (presbyacusis). Fibrocytes play a role in potassium recycling and maintenance of the endocochlear potential (EP). It has been proposed... Read More about Evaluation of cultured cochlear fibrocytes as a cell replacement therapy: comparison with native fibrocytes.