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Experienced males recognise and avoid mating with non-virgin females in the western flower thrips (2019)
Journal Article
Kirk. (2019). Experienced males recognise and avoid mating with non-virgin females in the western flower thrips. PloS one, https://doi.org/10.1371/journal.pone.0224115

The western flower thrips Frankliniella occidentalis (Thysanoptera: Thripidae) is a major insect pest on a wide range of crops throughout the world. There are several unexplained aspects of the mating behaviour, particularly in relation to male-male... Read More about Experienced males recognise and avoid mating with non-virgin females in the western flower thrips.

High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation (2019)
Journal Article
Taxiarchi, C., Kranjc, N., Kriezis, A., Kyrou, K., Bernardini, F., Russell, S., …Galizi, R. (2019). High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation. Scientific reports, 14841 - ?. https://doi.org/10.1038/s41598-019-51181-1

Although of high priority for the development of genetic tools to control malaria-transmitting mosquitoes, only a few germline-specific regulatory regions have been characterised to date and the presence of global regulatory mechanisms, such as dosag... Read More about High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation.

A Further Unique Chondroitin Sulfate from the shrimp Litopenaeus vannamei with Antithrombin Activity that Modulates Acute Inflammation (2019)
Journal Article
Palhares, L., Brito, A., Andrade De Lima, M., Nader, H., London, J., Barsukov, I., …Chavante, S. (2019). A Further Unique Chondroitin Sulfate from the shrimp Litopenaeus vannamei with Antithrombin Activity that Modulates Acute Inflammation. Carbohydrate Polymers, 115031--115031. https://doi.org/10.1016/j.carbpol.2019.115031

The detailed structure of a further Chondroitin Sulfate from Litopenaeus vannamei shrimp (sCS) is described. The backbone structure was established by 1H/13C NMR, which identified 3-O-sulfated GlcA, 4-O-sulfated GalNAc, 6-O-sulfated GalNAc, and 4,6-d... Read More about A Further Unique Chondroitin Sulfate from the shrimp Litopenaeus vannamei with Antithrombin Activity that Modulates Acute Inflammation.

Overwintering of the western flower thrips in outdoor strawberry crops (2019)
Journal Article
Kirk. (2019). Overwintering of the western flower thrips in outdoor strawberry crops. Journal of Pest Science, https://doi.org/10.1007/s10340-019-01163-z

The western flower thrips, Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), is a major pest of semi-protected strawberry crops in the UK. These crops are grown outdoors but sheltered by clear polythene tunnels during the growing seaso... Read More about Overwintering of the western flower thrips in outdoor strawberry crops.

Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine. (2019)
Journal Article
Paterson, J. M., Shaw, A. J., Burns, I., Dodds, A. W., Prasad, A., Reid, K. B., …Shrive, A. K. (2019). Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine. Journal of biological chemistry, 294(45), 17155-17165. https://doi.org/10.1074/jbc.RA119.010271

Bovine conglutinin is an immune protein that is involved in host resistance to microbes and parasites and interacts with complement component iC3b, agglutinates erythrocytes, and neutralizes influenza A virus. Here, we determined the high-resolution... Read More about Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine..

Tools for the Quality Control of Pharmaceutical Heparin. (2019)
Journal Article
Devlin, A., Mycroft-West, C., Procter, P., Cooper, L., Guimond, S., Andrade De Lima, M., …Skidmore, M. (2019). Tools for the Quality Control of Pharmaceutical Heparin. Medicina, 55, 636 - 636. https://doi.org/10.3390/medicina55100636

Heparin is a vital pharmaceutical anticoagulant drug and remains one of the few naturally sourced pharmaceutical agents used clinically. Heparin possesses a structural order with up to four levels of complexity. These levels are subject to change bas... Read More about Tools for the Quality Control of Pharmaceutical Heparin..

A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells. (2019)
Journal Article
(2019). A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells. Proceedings of the National Academy of Sciences of the United States of America, 20743-20749. https://doi.org/10.1073/pnas.1908058116

Mechanoelectrical transducer (MET) currents were recorded from cochlear hair cells in mice with mutations of transmembrane channel-like protein TMC1 to study the effects on MET channel properties. We characterized a Tmc1 mouse with a single-amino-aci... Read More about A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells..

Quantifying the potential for bluetongue virus transmission in Danish cattle farms (2019)
Journal Article
Haider, N., Kjær, L. J., Skovgård, H., Nielsen, S. A., & Bødker, R. (2019). Quantifying the potential for bluetongue virus transmission in Danish cattle farms. Scientific reports, 9, Article 13466. https://doi.org/10.1038/s41598-019-49866-8

Abstract We used a mechanistic transmission model to estimate the number of infectious bites (IBs) generated per bluetongue virus (BTV) infected host (cattle) using estimated hourly microclimatic temperatures at 22,004 Danish cattle farms for the per... Read More about Quantifying the potential for bluetongue virus transmission in Danish cattle farms.

Semi-field and indoor setups to study malaria mosquito swarming behavior (2019)
Journal Article
(2019). Semi-field and indoor setups to study malaria mosquito swarming behavior. Parasites and Vectors, 446 -?. https://doi.org/10.1186/s13071-019-3688-0

BACKGROUND The recent resurgence of interest in sterile insect techniques to control vector mosquitoes has renewed interest in novel methods for observing mating behavior. Malarial vectors of the Anopheles gambiae complex are known to mate in swarms... Read More about Semi-field and indoor setups to study malaria mosquito swarming behavior.

BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring - recent advances and future perspectives. (2019)
Journal Article
(2019). BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring - recent advances and future perspectives. Journal of Synchrotron Radiation, 1843 -1850. https://doi.org/10.1107/S1600577519008981

Being able to visualize biology at the molecular level is essential for our understanding of the world. A structural biology approach reveals the molecular basis of disease processes and can guide the design of new drugs as well as aid in the optimiz... Read More about BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring - recent advances and future perspectives..

Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin. (2019)
Journal Article
(2019). Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin. Histochemistry and Cell Biology, https://doi.org/10.1007/s00418-019-01809-0

Aluminium is biologically reactive and its ability to potentiate the immune response has driven its inclusion in both veterinary and human vaccines. Consequently, the need for unequivocal visualisation of aluminium in vivo has created a focused resea... Read More about Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin..

Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants (2019)
Journal Article
Mendes, A., Meneghetti, M., Palladino, M., Justo, G., Sassaki, G., Fareed, J., …Nader, H. (2019). Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants. Molecules, 24, 2988--2988. https://doi.org/10.3390/molecules24162988

Nowadays, pharmaceutical heparin is purified from porcine and bovine intestinal mucosa. In the past decade there has been an ongoing concern about the safety of heparin, since in 2008, adverse effects associated with the presence of an oversulfated c... Read More about Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants.

The size of micro-crystalline tyrosine (MCT®) influences its recognition and uptake by THP-1 macrophages in vitro (2019)
Journal Article
(2019). The size of micro-crystalline tyrosine (MCT®) influences its recognition and uptake by THP-1 macrophages in vitro. RSC advances, 24505 - 24518. https://doi.org/10.1039/C9RA03831K

The physicochemical hallmarks of particulate immunopotentiators play a pivotal role with regards to their adjuvanticity in vivo. These properties have not been fully characterised in the case of MCT®, an amino acid-based adjuvant used as an alternati... Read More about The size of micro-crystalline tyrosine (MCT®) influences its recognition and uptake by THP-1 macrophages in vitro.

Anosmic migrating songbirds demonstrate a compensatory response following long-distance translocation: a radio-tracking study (2019)
Journal Article
Kishkinev, D., Anashina, A., Ishchenko, I., & Holland, R. A. (2019). Anosmic migrating songbirds demonstrate a compensatory response following long-distance translocation: a radio-tracking study. Journal of Ornithology, https://doi.org/10.1007/s10336-019-01698-z

Several studies have shown that experienced night-migratory songbirds can determine their position, but it has remained a mystery which cues and sensory mechanisms they use, in particular, those used to determine longitude (east–west position). One p... Read More about Anosmic migrating songbirds demonstrate a compensatory response following long-distance translocation: a radio-tracking study.

Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility (2019)
Journal Article
Silva, A. I., Haddon, J. E., Ahmed Syed, Y., Trent, S., Lin, T. E., Patel, Y., …Wilkinson, L. S. (2019). Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility. Nature communications, 10, Article 3455. https://doi.org/10.1038/s41467-019-11119-7

The biological basis of the increased risk for psychiatric disorders seen in 15q11.2 copy number deletion is unknown. Previous work has shown disturbances in white matter tracts in human carriers of the deletion. Here, in a novel rat model, we recapi... Read More about Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility.

Current versus future reproductive investment adaptive responses in adult Anopheles coluzzii malaria mosquitoes: hydric-stressed males give it all. (2019)
Journal Article
(2019). Current versus future reproductive investment adaptive responses in adult Anopheles coluzzii malaria mosquitoes: hydric-stressed males give it all. Parasites and Vectors, 377 - ?. https://doi.org/10.1186/s13071-019-3608-3

BACKGROUND: Life history theory predicts that an individual's current reproductive investment should depend on its future reproductive value. A variety of intrinsic biotic and extrinsic factors influence reproductive value, including age, health st... Read More about Current versus future reproductive investment adaptive responses in adult Anopheles coluzzii malaria mosquitoes: hydric-stressed males give it all..

Using drones and sirens to elicit avoidance behaviour in white rhinoceros as an anti-poaching tactic. (2019)
Journal Article
(2019). Using drones and sirens to elicit avoidance behaviour in white rhinoceros as an anti-poaching tactic. Proceedings of the Royal Society B: Biological Sciences, 20191135 - ?. https://doi.org/10.1098/rspb.2019.1135

Poaching fuelled by international trade in horn caused the deaths of over 1000 African rhinoceros (Ceratotherium simum and Diceros bicornis) per year between 2013 and 2017. Deterrents, which act to establish avoidance behaviours in animals, have the... Read More about Using drones and sirens to elicit avoidance behaviour in white rhinoceros as an anti-poaching tactic..

Catch me if you can: the influence of refuge / trap design, previous feeding experience, and semiochemical lures on vine weevil (Coleoptera: Curculionidae) monitoring success. (2019)
Journal Article
(2019). Catch me if you can: the influence of refuge / trap design, previous feeding experience, and semiochemical lures on vine weevil (Coleoptera: Curculionidae) monitoring success. Pest Management Science, https://doi.org/10.1002/ps.5545

BACKGROUND: Vine weevil, Otiorhynchus sulcatus F. (Coleoptera: Curculionidae), is one of the most economically important pest species of berry and ornamental crops globally. Monitoring this nocturnal pest can be difficult and time consuming and the... Read More about Catch me if you can: the influence of refuge / trap design, previous feeding experience, and semiochemical lures on vine weevil (Coleoptera: Curculionidae) monitoring success..