All Outputs (857)

Behavioural and Electrophysiological Responses of Female Anopheles gambiae Mosquitoes to Volatiles from a Mango Bait (2020)
Journal Article
Okumu, F., Tripet, F., Bruce, T., Sobhy, I., Roberts, J., & Meza, F. (2020). Behavioural and Electrophysiological Responses of Female Anopheles gambiae Mosquitoes to Volatiles from a Mango Bait. Journal of Chemical Ecology, 387-396. https://doi.org/10.1007/s10886-020-01172-8

Attractive Toxic Sugar Baits (ATSB) are used in a "lure-and-kill" approach for management of the malaria vector Anopheles gambiae, but the active chemicals were previously unknown. Here we collected volatiles from a mango, Mangifera indica, juice bai... Read More about Behavioural and Electrophysiological Responses of Female Anopheles gambiae Mosquitoes to Volatiles from a Mango Bait.

A diagnostic real-time PCR assay for the rapid identification of the tomato-potato psyllid, Bactericera cockerelli (Šulc, 1909) and development of a psyllid barcoding database (2020)
Journal Article
Sumner-Kalkun, J., Sjölund, M., Arnsdorf, Y., Carnegie, M., Highet, F., Ouvrard, D., …Kenyon, D. (2020). A diagnostic real-time PCR assay for the rapid identification of the tomato-potato psyllid, Bactericera cockerelli (Šulc, 1909) and development of a psyllid barcoding database. PloS one, 15(3), Article e0230741. https://doi.org/10.1371/journal.pone.0230741

The accurate and rapid identification of insect pests is an important step in the prevention and control of outbreaks in areas that are otherwise pest free. The potato-tomato psyllid Bactericera cockerelli (Šulc, 1909) is the main vector of ‘Candidat... Read More about A diagnostic real-time PCR assay for the rapid identification of the tomato-potato psyllid, Bactericera cockerelli (Šulc, 1909) and development of a psyllid barcoding database.

Lead Optimization of Dehydroemetine for Repositioned Use in Malaria. (2020)
Journal Article
(2020). Lead Optimization of Dehydroemetine for Repositioned Use in Malaria. Antimicrobial Agents and Chemotherapy, https://doi.org/10.1128/AAC.01444-19

Drug repositioning offers an effective alternative to de novo drug design to tackle the urgent need for novel antimalarial treatments. The antiamoebic compound emetine dihydrochloride has been identified as a potent in vitro inhibitor of the multidru... Read More about Lead Optimization of Dehydroemetine for Repositioned Use in Malaria..

Microbiome: Evolution in a World of Interaction. (2020)
Journal Article
King, K. C., Stevens, E., & Drew, G. C. (2020). Microbiome: Evolution in a World of Interaction. Current Biology, 30(6), R265-R267. https://doi.org/10.1016/j.cub.2020.02.010

Ecological interactions can generate strong selection. Two new studies reveal that the tempo and patterns of evolutionary change in a mammalian gut commensal can be altered dramatically during interactions with both the host and its microbiome.

Application of the Random Encounter Model in citizen science projects to monitor animal densities (2020)
Journal Article
(2020). Application of the Random Encounter Model in citizen science projects to monitor animal densities. Remote Sensing in Ecology and Conservation, https://doi.org/10.1002/rse2.153

Abundance and density are vital metrics for assessing a species’ conservation status and for developing effective management strategies. Remote-sensing cameras are being used increasingly as part of citizen science projects to monitor wildlife, but c... Read More about Application of the Random Encounter Model in citizen science projects to monitor animal densities.

Genetic structure of regional water vole populations and footprints of reintroductions: a case study from southeast England (2020)
Journal Article
(2020). Genetic structure of regional water vole populations and footprints of reintroductions: a case study from southeast England. Conservation Genetics, https://doi.org/10.1007/s10592-020-01268-4

An important consideration when implementing species management is preserving genetic variation, which is fundamental to the long-term persistence of populations and adaptive potential of the species. The European water vole Arvicola amphibius is of... Read More about Genetic structure of regional water vole populations and footprints of reintroductions: a case study from southeast England.

Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model (2020)
Journal Article
Paape, D., Prendergast, C., Price, H., Doehl, J., & Smith, D. (2020). Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model. Parasites and Vectors, 13, Article 132. https://doi.org/10.1186/s13071-020-3999-1

Background: Proving that specifc genes are essential for the intracellular viability of Leishmania parasites within macrophages remains a challenge for the identifcation of suitable targets for drug development. This is especially evident in the ab... Read More about Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model.

Evaluation of NanoLuc, RedLuc and Luc2 as bioluminescent reporters in a cutaneous leishmaniasis model (2020)
Journal Article
Agostino, V., Trinconi, C., Galuppo, M., Price, H., & Uliana, S. (2020). Evaluation of NanoLuc, RedLuc and Luc2 as bioluminescent reporters in a cutaneous leishmaniasis model. Acta tropica, 206, Article 105444. https://doi.org/10.1016/j.actatropica.2020.105444

New drugs for the treatment of human leishmaniasis are urgently needed, considering the limitations of current available options. However, pre-clinical evaluation of drug candidates for leishmaniasis is challenging. The use of luciferase-expressing p... Read More about Evaluation of NanoLuc, RedLuc and Luc2 as bioluminescent reporters in a cutaneous leishmaniasis model.

Physico-Chemically Distinct Nanomaterials Synthesized from Derivates of a Poly(Anhydride) Diversify the Spectrum of Loadable Antibiotics. (2020)
Journal Article
Mira, A., Codina, H., Jenkins, S., Rodriguez-Diaz, J., Mallavia, R., Falco, A., & Sainz-Urruela, C. (2020). Physico-Chemically Distinct Nanomaterials Synthesized from Derivates of a Poly(Anhydride) Diversify the Spectrum of Loadable Antibiotics. Nanomaterials, https://doi.org/10.3390/nano10030486

Recent advances in the field of nanotechnology such as nanoencapsulation offer new biomedical applications, potentially increasing the scope and efficacy of therapeutic drug delivery. In addition, the discovery and development of novel biocompatible... Read More about Physico-Chemically Distinct Nanomaterials Synthesized from Derivates of a Poly(Anhydride) Diversify the Spectrum of Loadable Antibiotics..

Are insects declining and at what rate? An analysis of standardised, systematic catches of aphid and moth abundances across Great Britain (2020)
Journal Article
Bell, J., Blumgart, D., & Shortall, C. (2020). Are insects declining and at what rate? An analysis of standardised, systematic catches of aphid and moth abundances across Great Britain. Insect Conservation and Diversity, 13(2), 115-126. https://doi.org/10.1111/icad.12412

Although we have known anecdotally that insects have been declining in Great Britain for more than 100 years, insect declines have only been statistically estimated over the last 20 years. Estimation of the rate of those declines is still hotly debat... Read More about Are insects declining and at what rate? An analysis of standardised, systematic catches of aphid and moth abundances across Great Britain.

Outside the Military "Bubble": Life After Service for UK Ex-armed Forces Personnel (2020)
Journal Article
Gordon, K., Burnell, K., & Wilson, C. (2020). Outside the Military "Bubble": Life After Service for UK Ex-armed Forces Personnel. Frontiers in Public Health, 8, Article 50. https://doi.org/10.3389/fpubh.2020.00050

Military personnel who have seen active service can be affected by their experiences. Much of the literature on the mental and physical health battles faced by men and women who leave the Armed Forces is dominated by research in the United States (US... Read More about Outside the Military "Bubble": Life After Service for UK Ex-armed Forces Personnel.

Promoting Patient Utilization of Outpatient Cardiac Rehabilitation: A JOINT INTERNATIONAL COUNCIL AND CANADIAN ASSOCIATION OF CARDIOVASCULAR PREVENTION AND REHABILITATION POSITION STATEMENT. (2020)
Journal Article
Santiago de Araújo Pio, C., Beckie, T., Varnfield, M., Sarrafzadegan, N., Babu, A., Baidya, S., …Grace, S. (2020). Promoting Patient Utilization of Outpatient Cardiac Rehabilitation: A JOINT INTERNATIONAL COUNCIL AND CANADIAN ASSOCIATION OF CARDIOVASCULAR PREVENTION AND REHABILITATION POSITION STATEMENT. Journal of Cardiopulmonary Rehabilitation and Prevention, 79 - 86. https://doi.org/10.1097/HCR.0000000000000474

PURPOSE: Cardiac rehabilitation (CR) is a recommendation in international clinical practice guidelines given its benefits; however, use is suboptimal. The purpose of this position statement was to translate evidence on interventions that increase CR... Read More about Promoting Patient Utilization of Outpatient Cardiac Rehabilitation: A JOINT INTERNATIONAL COUNCIL AND CANADIAN ASSOCIATION OF CARDIOVASCULAR PREVENTION AND REHABILITATION POSITION STATEMENT..

Is Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic. Lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future (2020)
Journal Article
Kapata, N., Ihekweazu, C., Ntoumi, F., Raji, T., Chanda-Kapata, P., Mwaba, P., …Zumla, A. (2020). Is Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic. Lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future. International Journal of Infectious Diseases, 93, 233 - 236. https://doi.org/10.1016/j.ijid.2020.02.049

Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America (2020)
Journal Article
Haider, N., Yavlinsky, A., Simons, D., Yusuf Osman, A., Ntoumi, F., Zumla, A., & Kock, R. (2020). Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America. Epidemiology and Infection, 148, Article e41. https://doi.org/10.1017/s0950268820000424

Novel Coronavirus (2019-nCoV [SARS-COV-2]) was detected in humans during the last week of December 2019 at Wuhan city in China, and caused 24 554 cases in 27 countries and territories as of 5 February 2020. The objective of this study was to estimate... Read More about Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America.

Aluminium in Brain Tissue in Non-neurodegenerative/Non-neurodevelopmental Disease: A Comparison with Multiple Sclerosis (2020)
Journal Article
(2020). Aluminium in Brain Tissue in Non-neurodegenerative/Non-neurodevelopmental Disease: A Comparison with Multiple Sclerosis. Exposure and Health, https://doi.org/10.1007/s12403-020-00346-9

Human exposure to aluminium is a burgeoning issue. The brain is a sink for systemically available aluminium and a putative target of neurotoxicity. An increasing number of studies continue to confirm the presence of aluminium in human brain tissue th... Read More about Aluminium in Brain Tissue in Non-neurodegenerative/Non-neurodevelopmental Disease: A Comparison with Multiple Sclerosis.

Vertical farming systems bring new considerations for pest and disease management (2020)
Journal Article
Roberts, J., Bruce, T., Monaghan, J., Pope, T., Leather, S., & Beacham, A. (2020). Vertical farming systems bring new considerations for pest and disease management. Annals of Applied Biology, 226 - 232. https://doi.org/10.1111/aab.12587

Abstract Vertical farming is an emerging area of food production that aims to provide sustainable intensification of agriculture by maximising the obtainable yield per unit area of land. This approach commonly utilises stacked horizontal levels of cr... Read More about Vertical farming systems bring new considerations for pest and disease management.

Cathepsin B-associated Activation of Amyloidogenic Pathway in Murine Mucopolysaccharidosis Type I Brain Cortex (2020)
Journal Article
Viana, G. M., Gonzalez, E. A., Palacio Alvarez, M. M., Cavalheiro, R. P., do Nascimento, C. C., Baldo, G., …Nader, H. B. (2020). Cathepsin B-associated Activation of Amyloidogenic Pathway in Murine Mucopolysaccharidosis Type I Brain Cortex. International Journal of Molecular Sciences, 21, https://doi.org/10.3390/ijms21041459

Mucopolysaccharidosis type I (MPS I) is caused by genetic deficiency of alpha-l-iduronidase and impairment of lysosomal catabolism of heparan sulfate and dermatan sulfate. In the brain, these substrates accumulate in the lysosomes of neurons and glia... Read More about Cathepsin B-associated Activation of Amyloidogenic Pathway in Murine Mucopolysaccharidosis Type I Brain Cortex.

Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018 (2020)
Journal Article
Ghosh, S., Rana, M. S., Islam, M. K., Chowdhury, S., Haider, N., Kafi, M. A. H., …Jhora, S. T. (2020). Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018. Scientific Reports, 10(1), Article ARTN 2410. https://doi.org/10.1038/s41598-020-59109-w

AbstractVaccinating dogs against rabies is an effective means of reducing human rabies. We subjected 1327 clinically diagnosed human rabies death and mass dog vaccination (MDV) data during 2006–2018 to quantify the impacts of MDV on human rabies inci... Read More about Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018.

Climate warming disrupts mast seeding and its fitness benefits in European beech. (2020)
Journal Article
(2020). Climate warming disrupts mast seeding and its fitness benefits in European beech. Nature Plants, 88 - 94. https://doi.org/10.1038/s41477-020-0592-8

Many plants benefit from synchronous year-to-year variation in seed production, called masting. Masting benefits plants because it increases the efficiency of pollination and satiates predators, which reduces seed loss. Here, using a 39-year-long dat... Read More about Climate warming disrupts mast seeding and its fitness benefits in European beech..

Monomeric C-Reactive Protein in Serum With Markedly Elevated CRP Levels Shares Common Calcium-Dependent Ligand Binding Properties With an in vitro Dissociated Form of C-Reactive Protein (2020)
Journal Article
Williams, R. D., Moran, J. A., Fryer, A. A., Littlejohn, J. R., Williams, H. M., Greenhough, T. J., & Shrive, A. K. (2020). Monomeric C-Reactive Protein in Serum With Markedly Elevated CRP Levels Shares Common Calcium-Dependent Ligand Binding Properties With an in vitro Dissociated Form of C-Reactive Protein. Frontiers in Immunology, 11, Article ARTN 115. https://doi.org/10.3389/fimmu.2020.00115

A monomeric form of C-reactive protein (CRP) which precipitates with cell wall pneumococcal C polysaccharide (CWPS) and retains the ability to reversibly bind to its ligand phosphocholine has been produced through urea-induced dissociation at an opti... Read More about Monomeric C-Reactive Protein in Serum With Markedly Elevated CRP Levels Shares Common Calcium-Dependent Ligand Binding Properties With an in vitro Dissociated Form of C-Reactive Protein.