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Molecular characterization of group A rotavirus from rhesus macaques (Macaca mulatta) at human-wildlife interfaces in Bangladesh (2019)
Journal Article
Islam, A., Rahman, M. Z., Miah, M., Hossain, M. E., Haider, N., Rostal, M. K., …Epstein, J. H. (2020). Molecular characterization of group A rotavirus from rhesus macaques (Macaca mulatta) at human-wildlife interfaces in Bangladesh. Transboundary and Emerging Diseases, 67(2), 956-966. https://doi.org/10.1111/tbed.13431

Group A rotavirus (RVA) is an important cause of diarrhoea in people, especially children, and animals globally. Due to the segmented nature of the RVA genome, animal RVA strains have the potential to adapt to the human host through reassortment with... Read More about Molecular characterization of group A rotavirus from rhesus macaques (Macaca mulatta) at human-wildlife interfaces in Bangladesh.

Moth biomass has fluctuated over 50 years in Britain but lacks a clear trend (2019)
Journal Article
Macgregor, C. J., Williams, J. H., Bell, J. R., & Thomas, C. D. (2019). Moth biomass has fluctuated over 50 years in Britain but lacks a clear trend. Nature Ecology & Evolution, 3, 1645–1649. https://doi.org/10.1038/s41559-019-1028-6

Steep insect biomass declines ('insectageddon') have been widely reported, despite a lack of continuously collected biomass data from replicated long-term monitoring sites. Such severe declines are not supported by the world’s longest running insect... Read More about Moth biomass has fluctuated over 50 years in Britain but lacks a clear trend.

Genetic structure at national and regional scale in a long-distance dispersing pest organism, the bird cherry–oat aphid Rhopalosiphum padi (2019)
Journal Article
Morales-Hojas, R., Gonzalez-Uriarte, A., Alvira Iraizoz, F., Jenkins, T., Alderson, L., Kruger, T., …Bell, J. R. (2019). Genetic structure at national and regional scale in a long-distance dispersing pest organism, the bird cherry–oat aphid Rhopalosiphum padi. bioRxiv, https://doi.org/10.1101/829986

Genetic diversity is determinant for pest species’ success and vector competence. Understanding the ecological and evolutionary processes that determine the genetic diversity is fundamental to help identify the spatial scale at which pest populations... Read More about Genetic structure at national and regional scale in a long-distance dispersing pest organism, the bird cherry–oat aphid Rhopalosiphum padi.

Autophagy is inhibited by ubiquitin ligase activity in the nervous system (2019)
Journal Article
Crawley, O., Opperman, K. J., Desbois, M., Adrados, I., Borgen, M. A., Giles, A. C., …Grill, B. (2019). Autophagy is inhibited by ubiquitin ligase activity in the nervous system. Nature Communications, 10, Article 5017. https://doi.org/10.1038/s41467-019-12804-3

Autophagy is an intracellular catabolic process prominent in starvation, aging and disease. Neuronal autophagy is particularly important, as it affects the development and function of the nervous system, and is heavily implicated in neurodegenerative... Read More about Autophagy is inhibited by ubiquitin ligase activity in the nervous system.

Gene expression profile of Aedes aegypti females in courtship and mating. (2019)
Journal Article
(2019). Gene expression profile of Aedes aegypti females in courtship and mating. Scientific reports, 15492 - ?. https://doi.org/10.1038/s41598-019-52268-5

Aedes aegypti is the most synanthropic and anthropophilic mosquito of Culicidae. This species always cohabits with humans and is extremely opportunistic. Vector dispersal is directly related to the ability of the females on successfully finding a mat... Read More about Gene expression profile of Aedes aegypti females in courtship and mating..

Climate-induced phenology shifts linked to range expansions in species with multiple reproductive cycles per year (2019)
Journal Article
Macgregor, C. J., Thomas, C. D., Roy, D. B., Beaumont, M. A., Bell, J. R., Brereton, T., …Hill, J. K. (2019). Climate-induced phenology shifts linked to range expansions in species with multiple reproductive cycles per year. Nature Communications, 10, Article 4455. https://doi.org/10.1038/s41467-019-12479-w

Advances in phenology (the annual timing of species’ life-cycles) in response to climate change are generally viewed as bioindicators of climate change, but have not been considered as predictors of range expansions. Here, we show that phenology adva... Read More about Climate-induced phenology shifts linked to range expansions in species with multiple reproductive cycles per year.

Experienced males recognise and avoid mating with non-virgin females in the western flower thrips (2019)
Journal Article
Kirk. (2019). Experienced males recognise and avoid mating with non-virgin females in the western flower thrips. PloS one, https://doi.org/10.1371/journal.pone.0224115

The western flower thrips Frankliniella occidentalis (Thysanoptera: Thripidae) is a major insect pest on a wide range of crops throughout the world. There are several unexplained aspects of the mating behaviour, particularly in relation to male-male... Read More about Experienced males recognise and avoid mating with non-virgin females in the western flower thrips.

High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation (2019)
Journal Article
Taxiarchi, C., Kranjc, N., Kriezis, A., Kyrou, K., Bernardini, F., Russell, S., …Galizi, R. (2019). High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation. Scientific reports, 14841 - ?. https://doi.org/10.1038/s41598-019-51181-1

Although of high priority for the development of genetic tools to control malaria-transmitting mosquitoes, only a few germline-specific regulatory regions have been characterised to date and the presence of global regulatory mechanisms, such as dosag... Read More about High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation.

A Further Unique Chondroitin Sulfate from the shrimp Litopenaeus vannamei with Antithrombin Activity that Modulates Acute Inflammation (2019)
Journal Article
Palhares, L., Brito, A., Andrade De Lima, M., Nader, H., London, J., Barsukov, I., …Chavante, S. (2019). A Further Unique Chondroitin Sulfate from the shrimp Litopenaeus vannamei with Antithrombin Activity that Modulates Acute Inflammation. Carbohydrate Polymers, 115031--115031. https://doi.org/10.1016/j.carbpol.2019.115031

The detailed structure of a further Chondroitin Sulfate from Litopenaeus vannamei shrimp (sCS) is described. The backbone structure was established by 1H/13C NMR, which identified 3-O-sulfated GlcA, 4-O-sulfated GalNAc, 6-O-sulfated GalNAc, and 4,6-d... Read More about A Further Unique Chondroitin Sulfate from the shrimp Litopenaeus vannamei with Antithrombin Activity that Modulates Acute Inflammation.

Overwintering of the western flower thrips in outdoor strawberry crops (2019)
Journal Article
Kirk. (2019). Overwintering of the western flower thrips in outdoor strawberry crops. Journal of Pest Science, https://doi.org/10.1007/s10340-019-01163-z

The western flower thrips, Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), is a major pest of semi-protected strawberry crops in the UK. These crops are grown outdoors but sheltered by clear polythene tunnels during the growing seaso... Read More about Overwintering of the western flower thrips in outdoor strawberry crops.

Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine. (2019)
Journal Article
Paterson, J. M., Shaw, A. J., Burns, I., Dodds, A. W., Prasad, A., Reid, K. B., …Shrive, A. K. (2019). Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine. Journal of biological chemistry, 294(45), 17155-17165. https://doi.org/10.1074/jbc.RA119.010271

Bovine conglutinin is an immune protein that is involved in host resistance to microbes and parasites and interacts with complement component iC3b, agglutinates erythrocytes, and neutralizes influenza A virus. Here, we determined the high-resolution... Read More about Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine..

Tools for the Quality Control of Pharmaceutical Heparin. (2019)
Journal Article
Devlin, A., Mycroft-West, C., Procter, P., Cooper, L., Guimond, S., Andrade De Lima, M., …Skidmore, M. (2019). Tools for the Quality Control of Pharmaceutical Heparin. Medicina, 55, 636 - 636. https://doi.org/10.3390/medicina55100636

Heparin is a vital pharmaceutical anticoagulant drug and remains one of the few naturally sourced pharmaceutical agents used clinically. Heparin possesses a structural order with up to four levels of complexity. These levels are subject to change bas... Read More about Tools for the Quality Control of Pharmaceutical Heparin..

A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells. (2019)
Journal Article
(2019). A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells. Proceedings of the National Academy of Sciences of the United States of America, 20743-20749. https://doi.org/10.1073/pnas.1908058116

Mechanoelectrical transducer (MET) currents were recorded from cochlear hair cells in mice with mutations of transmembrane channel-like protein TMC1 to study the effects on MET channel properties. We characterized a Tmc1 mouse with a single-amino-aci... Read More about A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells..

Quantifying the potential for bluetongue virus transmission in Danish cattle farms (2019)
Journal Article
Haider, N., Kjær, L. J., Skovgård, H., Nielsen, S. A., & Bødker, R. (2019). Quantifying the potential for bluetongue virus transmission in Danish cattle farms. Scientific reports, 9, Article 13466. https://doi.org/10.1038/s41598-019-49866-8

Abstract We used a mechanistic transmission model to estimate the number of infectious bites (IBs) generated per bluetongue virus (BTV) infected host (cattle) using estimated hourly microclimatic temperatures at 22,004 Danish cattle farms for the per... Read More about Quantifying the potential for bluetongue virus transmission in Danish cattle farms.

Semi-field and indoor setups to study malaria mosquito swarming behavior (2019)
Journal Article
(2019). Semi-field and indoor setups to study malaria mosquito swarming behavior. Parasites and Vectors, 446 -?. https://doi.org/10.1186/s13071-019-3688-0

BACKGROUND The recent resurgence of interest in sterile insect techniques to control vector mosquitoes has renewed interest in novel methods for observing mating behavior. Malarial vectors of the Anopheles gambiae complex are known to mate in swarms... Read More about Semi-field and indoor setups to study malaria mosquito swarming behavior.

BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring - recent advances and future perspectives. (2019)
Journal Article
(2019). BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring - recent advances and future perspectives. Journal of Synchrotron Radiation, 1843 -1850. https://doi.org/10.1107/S1600577519008981

Being able to visualize biology at the molecular level is essential for our understanding of the world. A structural biology approach reveals the molecular basis of disease processes and can guide the design of new drugs as well as aid in the optimiz... Read More about BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring - recent advances and future perspectives..

Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin. (2019)
Journal Article
(2019). Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin. Histochemistry and Cell Biology, https://doi.org/10.1007/s00418-019-01809-0

Aluminium is biologically reactive and its ability to potentiate the immune response has driven its inclusion in both veterinary and human vaccines. Consequently, the need for unequivocal visualisation of aluminium in vivo has created a focused resea... Read More about Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin..