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Changes in the distribution of red foxes (Vulpes vulpes) in urban areas in Great Britain: findings and limitations of a media-driven nationwide survey. (2014)
Journal Article
(2014). Changes in the distribution of red foxes (Vulpes vulpes) in urban areas in Great Britain: findings and limitations of a media-driven nationwide survey. PloS one, e99059 - ?. https://doi.org/10.1371/journal.pone.0099059

Urbanization is one of the major forms of habitat alteration occurring at the present time. Although this is typically deleterious to biodiversity, some species flourish within these human-modified landscapes, potentially leading to negative and/or p... Read More about Changes in the distribution of red foxes (Vulpes vulpes) in urban areas in Great Britain: findings and limitations of a media-driven nationwide survey..

A synthetic sex ratio distortion system for the control of the human malaria mosquito. (2014)
Journal Article
Galizi, R., Doyle, L. A., Menichelli, M., Bernardini, F., Deredec, A., Burt, A., …Crisanti, A. (2014). A synthetic sex ratio distortion system for the control of the human malaria mosquito. Nature communications, 3977 - ?. https://doi.org/10.1038/ncomms4977

It has been theorized that inducing extreme reproductive sex ratios could be a method to suppress or eliminate pest populations. Limited knowledge about the genetic makeup and mode of action of naturally occurring sex distorters and the prevalence of... Read More about A synthetic sex ratio distortion system for the control of the human malaria mosquito..

Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range. (2014)
Journal Article
Forrester-Soto. (2014). Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range. Virology Journal, 97 - 97. https://doi.org/10.1186/1743-422X-11-97

Background The family Mesoniviridae (order Nidovirales) comprises of a group of positive-sense, single-stranded RNA ([+]ssRNA) viruses isolated from mosquitoes. Findings Thirteen novel insect-specific virus isolates were obtained from mosquitoes c... Read More about Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range..

Feeding common carp Cyprinus carpio with β-glucan supplemented diet stimulates C-reactive protein and complement immune acute phase responses following PAMPs injection (2014)
Journal Article
Pionnier, N., Falco, A., Miest, J. J., Shrive, A. K., & Hoole, D. (2014). Feeding common carp Cyprinus carpio with β-glucan supplemented diet stimulates C-reactive protein and complement immune acute phase responses following PAMPs injection. Fish and Shellfish Immunology, 39(2), 285-295. https://doi.org/10.1016/j.fsi.2014.05.008

Site-specific genetic engineering of the Anopheles gambiae Y chromosome. (2014)
Journal Article
Bernardini, F., Galizi, R., Menichelli, M., Papathanos, P., Dritsou, V., Marois, E., …Windbichler, N. (2014). Site-specific genetic engineering of the Anopheles gambiae Y chromosome. Proceedings of the National Academy of Sciences of the United States of America, 7600 - 7605. https://doi.org/10.1073/pnas.1404996111

Despite its function in sex determination and its role in driving genome evolution, the Y chromosome remains poorly understood in most species. Y chromosomes are gene-poor, repeat-rich and largely heterochromatic and therefore represent a difficult t... Read More about Site-specific genetic engineering of the Anopheles gambiae Y chromosome..

The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction. (2014)
Journal Article
(2014). The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction. Nucleic acids research, 7113 - 7131. https://doi.org/10.1093/nar/gku322

Babesia spp. are tick-borne, intraerythrocytic hemoparasites that use antigenic variation to resist host immunity, through sequential modification of the parasite-derived variant erythrocyte surface antigen (VESA) expressed on the infected red blood... Read More about The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction..

An investigation into the protein composition of the teneral Glossina morsitans morsitans peritrophic matrix. (2014)
Journal Article
(2014). An investigation into the protein composition of the teneral Glossina morsitans morsitans peritrophic matrix. PLoS Neglected Tropical Diseases, e2691 - ?. https://doi.org/10.1371/journal.pntd.0002691

BACKGROUND: Tsetse flies serve as biological vectors for several species of African trypanosomes. In order to survive, proliferate and establish a midgut infection, trypanosomes must cross the tsetse fly peritrophic matrix (PM), which is an acellular... Read More about An investigation into the protein composition of the teneral Glossina morsitans morsitans peritrophic matrix..

Amplicon -based Metagenomic Analysis of Mixed Fungal Samples using Proton Release Amplicon Sequencing (2014)
Journal Article
Tonge, D., Pashley, C., & Gant, T. (2014). Amplicon -based Metagenomic Analysis of Mixed Fungal Samples using Proton Release Amplicon Sequencing. PloS one, https://doi.org/10.1371/journal.pone.0093849

Next generation sequencing technology has revolutionised microbiology by allowing concurrent analysis of whole microbial communities. Here we developed and verified similar methods for the analysis of fungal communities using a proton release sequenc... Read More about Amplicon -based Metagenomic Analysis of Mixed Fungal Samples using Proton Release Amplicon Sequencing.

Biting by Anopheles funestus in broad daylight after use of long-lasting insecticidal nets: a new challenge to malaria elimination. (2014)
Journal Article
(2014). Biting by Anopheles funestus in broad daylight after use of long-lasting insecticidal nets: a new challenge to malaria elimination. Malaria Journal, -. https://doi.org/10.1186/1475-2875-13-125

BACKGROUND: Malaria control is mainly based on indoor residual spraying and insecticide-treated bed nets. The efficacy of these tools depends on the behaviour of mosquitoes, which varies by species. With resistance to insecticides, mosquitoes adapt t... Read More about Biting by Anopheles funestus in broad daylight after use of long-lasting insecticidal nets: a new challenge to malaria elimination..

Pleiotropic effects of extended blockade of CSF1R signaling in adult mice (2014)
Journal Article
Beard. (2014). Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. Journal of Leukocyte Biology, 265 - 274. https://doi.org/10.1189/jlb.2A0114-006R

We investigated the role of CSF1R signaling in adult mice using prolonged treatment with anti-CSF1R antibody. Mutation of the CSF1 gene in the op/op mouse produces numerous developmental abnormalities. Mutation of the CSF1R has an even more penetrant... Read More about Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.

Synthetic sex pheromone in a long-lasting lure attracts the visceral leishmaniasis vector, Lutzomyia longipalpis, for up to 12 weeks in Brazil (2014)
Journal Article
(2014). Synthetic sex pheromone in a long-lasting lure attracts the visceral leishmaniasis vector, Lutzomyia longipalpis, for up to 12 weeks in Brazil. PLoS Neglected Tropical Diseases, e2723 - ?. https://doi.org/10.1371/journal.pntd.0002723

Current control methodologies have not prevented the spread of visceral leishmaniasis (VL) across Brazil. Here, we describe the development of a new tool for controlling the sand fly vector of the disease: a long-lasting lure, which releases a synthe... Read More about Synthetic sex pheromone in a long-lasting lure attracts the visceral leishmaniasis vector, Lutzomyia longipalpis, for up to 12 weeks in Brazil.

Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder (2014)
Journal Article
Trent, S., Fry, J. P., Ojarikre, O. A., & Davies, W. (2014). Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder. Molecular Autism, 5, Article 21. https://doi.org/10.1186/2040-2392-5-21

Background The 39,XY*O mouse, which lacks the orthologues of the ADHD and autism candidate genes STS (steroid sulphatase) and ASMT (acetylserotonin O-methyltransferase), exhibits behavioural phenotypes relevant to developmental disorders. The neurob... Read More about Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder.

TRAF2 Facilitates Vaccinia Virus Replication by Promoting Rapid Virus Entry (2014)
Journal Article
Beard. (2014). TRAF2 Facilitates Vaccinia Virus Replication by Promoting Rapid Virus Entry. Journal of Virology, 3664 - 3677. https://doi.org/10.1128/JVI.03013-13

ABSTRACT Tumor necrosis factor receptor (TNFR)-associated factor 2 (TRAF2) is a pivotal intracellular mediator of signaling pathways downstream of TNFR1 and -2 with known pro- and antiviral effects. We investigated its role in the replication of the... Read More about TRAF2 Facilitates Vaccinia Virus Replication by Promoting Rapid Virus Entry.

Transgenic Anopheles gambiae expressing an antimalarial peptide suffer no significant fitness cost (2014)
Journal Article
(2014). Transgenic Anopheles gambiae expressing an antimalarial peptide suffer no significant fitness cost. PloS one, e88625 - ?. https://doi.org/10.1371/journal.pone.0088625

Mosquito-borne diseases present some of the greatest health challenges faced by the world today. In many cases, existing control measures are compromised by insecticide resistance, pathogen tolerance to drugs and the lack of effective vaccines. In li... Read More about Transgenic Anopheles gambiae expressing an antimalarial peptide suffer no significant fitness cost.

The evolution of massive stars and their spectra I. A non-rotating 60 Msun star from the zero-age main sequence to the pre-supernova stage (2014)
Journal Article
(2014). The evolution of massive stars and their spectra I. A non-rotating 60 Msun star from the zero-age main sequence to the pre-supernova stage. Astronomy & Astrophysics,

For the first time, the interior and spectroscopic evolution of a massive star is analyzed from the zero-age main sequence (ZAMS) to the pre-supernova (SN) stage. For this purpose, we combined stellar evolution models using the Geneva code and atmosp... Read More about The evolution of massive stars and their spectra I. A non-rotating 60 Msun star from the zero-age main sequence to the pre-supernova stage.

A Year In The Life Of: An Online Diary Of Keele Biochemistry Students’ Lives (2014)
Journal Article
(2014). A Year In The Life Of: An Online Diary Of Keele Biochemistry Students’ Lives. The Journal of Academic Development and Education, 15 -28

Students often find the transition from School to University and between levels difficult. During Year 1 in particular, retention levels can be impacted significantly if students have problems integrating socially, as well as academically. Universi... Read More about A Year In The Life Of: An Online Diary Of Keele Biochemistry Students’ Lives.

Differential effects of inbreeding and selection on male reproductive phenotype associated with the colonization and laboratory maintenance of Anopheles gambiae. (2014)
Journal Article
(2014). Differential effects of inbreeding and selection on male reproductive phenotype associated with the colonization and laboratory maintenance of Anopheles gambiae. Malaria Journal, 19 -?. https://doi.org/10.1186/1475-2875-13-19

BACKGROUND: Effective mating between laboratory-reared males and wild females is paramount to the success of vector control strategies aiming to decrease disease transmission via the release of sterile or genetically modified male mosquitoes. However... Read More about Differential effects of inbreeding and selection on male reproductive phenotype associated with the colonization and laboratory maintenance of Anopheles gambiae..