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Extended Multilocus Sequence Analysis to Describe the Global Population Structure of the Genus Brucella: Phylogeography and Relationship to Biovars (2016)
Journal Article
(2016). Extended Multilocus Sequence Analysis to Describe the Global Population Structure of the Genus Brucella: Phylogeography and Relationship to Biovars. Frontiers in Microbiology, https://doi.org/10.3389/fmicb.2016.02049

An extended multilocus sequence analysis (MLSA) scheme applicable to the Brucella, an expanding genus that includes zoonotic pathogens that severely impact animal and human health across large parts of the globe, was developed. The scheme, which exte... Read More about Extended Multilocus Sequence Analysis to Describe the Global Population Structure of the Genus Brucella: Phylogeography and Relationship to Biovars.

Isolation and characterization of native Bacillus thuringiensis strains from Saudi Arabia with enhanced larvicidal toxicity against the mosquito vector Anopheles gambiae (s.l.). (2016)
Journal Article
(2016). Isolation and characterization of native Bacillus thuringiensis strains from Saudi Arabia with enhanced larvicidal toxicity against the mosquito vector Anopheles gambiae (s.l.). Parasites and Vectors, 647 - ?. https://doi.org/10.1186/s13071-016-1922-6

BACKGROUND: Worldwide, mosquito vectors are transmitting several etiological agents of important human diseases, including malaria, causing millions of deaths every year. In Saudi Arabia, as elsewhere, vector-control is based mostly on chemical insec... Read More about Isolation and characterization of native Bacillus thuringiensis strains from Saudi Arabia with enhanced larvicidal toxicity against the mosquito vector Anopheles gambiae (s.l.)..

The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project. (2016)
Journal Article
(2016). The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project. Ecology and Evolution, 145 - 188. https://doi.org/10.1002/ece3.2579

The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multipl... Read More about The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project..

First Detection of Leishmania infantum in Domestic Dogs from Burkina Faso (West Africa) (2016)
Journal Article
Sangaré, I., Dabiré, R., Guiguemdé, R., Fournet, F., Price, H., Djibougou, A., …Banuls, A. (2016). First Detection of Leishmania infantum in Domestic Dogs from Burkina Faso (West Africa). Research Journal of Parasitology, 12(1), 27-32. https://doi.org/10.3923/jp.2017.27.32

Background and Objective: Human Visceral Leishmaniasis (HVL) is a systemic neglected tropical diseases and potentially lethal disease caused by infection with protozoan parasites of the Leishmania genus. In the causal, agent of HVL is L. infantum and... Read More about First Detection of Leishmania infantum in Domestic Dogs from Burkina Faso (West Africa).

Aluminium in brain tissue in familial Alzheimer's disease (2016)
Journal Article
(2016). Aluminium in brain tissue in familial Alzheimer's disease. Journal of Trace Elements in Medicine and Biology, 30 - 36. https://doi.org/10.1016/j.jtemb.2016.12.001

The genetic predispositions which describe a diagnosis of familial Alzheimer’s disease can be considered as cornerstones of the amyloid cascade hypothesis. Essentially they place the expression and metabolism of the amyloid precursor protein as the m... Read More about Aluminium in brain tissue in familial Alzheimer's disease.

Aluminium in brain tissue in familial Alzheimer’s disease (2016)
Journal Article
(2016). Aluminium in brain tissue in familial Alzheimer’s disease. Journal of Trace Elements in Medicine and Biology, 30-36. https://doi.org/10.1016/j.jtemb.2016.12.001

The genetic predispositions which describe a diagnosis of familial Alzheimer’s disease can be considered as cornerstones of the amyloid cascade hypothesis. Essentially they place the expression and metabolism of the amyloid precursor protein as the m... Read More about Aluminium in brain tissue in familial Alzheimer’s disease.

SEC-SANS: size exclusion chromatography combined in situ with small-angle neutron scattering. (2016)
Journal Article
(2016). SEC-SANS: size exclusion chromatography combined in situ with small-angle neutron scattering. Journal of Applied Crystallography, 2015 - 2020. https://doi.org/10.1107/S1600576716016514

The first implementation and use of an in situ size exclusion chromatography (SEC) system on a small-angle neutron scattering instrument (SANS) is described. The possibility of deploying such a system for biological solution scattering at the Institu... Read More about SEC-SANS: size exclusion chromatography combined in situ with small-angle neutron scattering..

Oxygen Costs of the Incremental Shuttle Walk Test in Cardiac Rehabilitation Participants: An Historical and Contemporary Analysis (2016)
Journal Article
Buckley, J., Cardoso, F., Sandercock, G., & Birkett, S. (2016). Oxygen Costs of the Incremental Shuttle Walk Test in Cardiac Rehabilitation Participants: An Historical and Contemporary Analysis. Sports Medicine, 1953 - 1962. https://doi.org/10.1007/s40279-016-0521-1

Background The incremental shuttle walk test (ISWT) is a standardised assessment for cardiac rehabilitation. Three studies have reported oxygen costs (VO2)/metabolic equivalents (METs) of the ISWT. In spite of classic representations from these stud... Read More about Oxygen Costs of the Incremental Shuttle Walk Test in Cardiac Rehabilitation Participants: An Historical and Contemporary Analysis.

Contrasting Roles of Deoxynivalenol and Nivalenol in Host-Mediated Interactions between Fusarium graminearum and Sitobion avenae (2016)
Journal Article
Drakulic, J., Kahar, M., Ajigboye, O., Bruce, T., & Ray, R. (2016). Contrasting Roles of Deoxynivalenol and Nivalenol in Host-Mediated Interactions between Fusarium graminearum and Sitobion avenae. Toxins, https://doi.org/10.3390/toxins8120353

Fusarium graminearum is the predominant causal species of Fusarium head blight in Europe and North America. Different chemotypes of the species exist, each producing a plethora of mycotoxins. Isolates of differing chemotypes produce nivalenol (NIV) a... Read More about Contrasting Roles of Deoxynivalenol and Nivalenol in Host-Mediated Interactions between Fusarium graminearum and Sitobion avenae.

Non-linear dose-response of aluminium hydroxide adjuvant particles: selective low dose neurotoxicity (2016)
Journal Article
(2016). Non-linear dose-response of aluminium hydroxide adjuvant particles: selective low dose neurotoxicity. Toxicology, 48-57. https://doi.org/10.1016/j.tox.2016.11.018

Abstract Aluminium (Al) oxyhydroxide (Alhydrogel®), the main adjuvant licensed for human and animal vaccines, consists of primary nanoparticles that spontaneously agglomerate. Concerns about its safety emerged following recognition of its unexpectedl... Read More about Non-linear dose-response of aluminium hydroxide adjuvant particles: selective low dose neurotoxicity.

Role of Protein Phosphatase 4 Regulatory Subunits in Myeloid Leukaemia (2016)
Presentation / Conference
Mourtada Maarabouni, M., Hanson, R., Sivanandan, C., & Ladna, A. (2016, November). Role of Protein Phosphatase 4 Regulatory Subunits in Myeloid Leukaemia. Presented at NCRI Cancer Conference, Liverpool

Abstract Background The serine/ threonine protein phosphatase 4 (PP4) has been identified to play a role in apoptosis and tumorigenesis. The PP4 holoenzyme consists of PP4 catalytic subunit (PP4c) which interacts with four different regulatory... Read More about Role of Protein Phosphatase 4 Regulatory Subunits in Myeloid Leukaemia.

Electrophysiological and behavioral responses of female African rice gall midge, Orseolia oryzivora Harris and Gagné, to host plant volatiles. (2016)
Journal Article
Ogah, E., Smart, L., Woodcock, C., Caulfield, J., Birkett, M., Pickett, J., …Bruce, T. (2016). Electrophysiological and behavioral responses of female African rice gall midge, Orseolia oryzivora Harris and Gagné, to host plant volatiles. Journal of Chemical Ecology, 13 - 16. https://doi.org/10.1007/s10886-016-0788-6

African rice gall midge, Orseolia oryzivora Harris and Gagné, is a major pest of rice in Africa. Depsite its economic importance, its chemical ecology is not well understood. Here, we assessed behavioral and electrophysiological responses of O. oryzi... Read More about Electrophysiological and behavioral responses of female African rice gall midge, Orseolia oryzivora Harris and Gagné, to host plant volatiles..

Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs (2016)
Journal Article
(2016). Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs. BMC Genomics, 859. https://doi.org/10.1186/s12864-016-3183-3

Background Malaria parasites of the genus Plasmodium possess large hyper-variable families of antigen-encoding genes. These are often variantly-expressed and are major virulence factors for immune evasion and the maintenance of chronic infections. Re... Read More about Recombination events among virulence genes in malaria parasites are associated with G-quadruplex-forming DNA motifs.

Cardiac Rehabilitation Delivery Model for Low-Resource Settings: An International Council of Cardiovascular Prevention and Rehabilitation Consensus Statement. (2016)
Journal Article
Grace, S., Turk-Adawi, K., Contractor, A., Atrey, A., Campbell, N., Derman, W., …Sarrafzadegan, N. (2016). Cardiac Rehabilitation Delivery Model for Low-Resource Settings: An International Council of Cardiovascular Prevention and Rehabilitation Consensus Statement. Progress in Cardiovascular Diseases, 303 - 322. https://doi.org/10.1016/j.pcad.2016.08.004

Cardiovascular disease (CVD) is a global epidemic, which is largely preventable. Cardiac rehabilitation (CR) is demonstrated to be efficacious and cost-effective for secondary prevention in high-income countries. Given its affordability, CR should be... Read More about Cardiac Rehabilitation Delivery Model for Low-Resource Settings: An International Council of Cardiovascular Prevention and Rehabilitation Consensus Statement..

Aphid Infestation Increases Fusarium langsethiae and T-2 and HT-2 Mycotoxins in Wheat (2016)
Journal Article
Drakulic, J., Ajigboye, O., Swarup, R., Bruce, T., & Ray, R. (2016). Aphid Infestation Increases Fusarium langsethiae and T-2 and HT-2 Mycotoxins in Wheat. Applied and Environmental Microbiology, 6548 - 6556. https://doi.org/10.1128/AEM.02343-16

Fusarium langsethiae is a fungal pathogen of cereal crops that is an increasing problem in northern Europe, but much of its epidemiology is poorly understood. The species produces the mycotoxins T-2 and HT-2, which are highly toxic. It was hypothesiz... Read More about Aphid Infestation Increases Fusarium langsethiae and T-2 and HT-2 Mycotoxins in Wheat.

Food availability and population structure: How do clumped and abundant sources of carrion affect the genetic diversity of the black-backed jackal? (2016)
Journal Article
(2016). Food availability and population structure: How do clumped and abundant sources of carrion affect the genetic diversity of the black-backed jackal?. Journal of Zoology, 184 - 192. https://doi.org/10.1111/jzo.12407

Carnivores frequently come into conflict with humans in agricultural and livestock-producing areas around the world. Understanding their fidelity and dispersal patterns in response to food availability is therefore important given the effort invested... Read More about Food availability and population structure: How do clumped and abundant sources of carrion affect the genetic diversity of the black-backed jackal?.

Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity. (2016)
Journal Article
Forrester-Soto. (2016). Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity. Scientific reports, 35819 - 35819. https://doi.org/10.1038/srep35819

The trade-off hypothesis, the current paradigm of arbovirus evolution, proposes that cycling between vertebrate and invertebrate hosts presents significant constraints on genetic change of arboviruses. Studying these constraints in mosquito-borne vir... Read More about Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity..