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All Outputs (137)

Functional analysis of the 5′ untranslated region of the phosphoglutamase 2 transcript in Plasmodium falciparum (2013)
Journal Article
Hasenkamp, S., Russell, K., Ullah, I., & Horrocks, P. (2013). Functional analysis of the 5′ untranslated region of the phosphoglutamase 2 transcript in Plasmodium falciparum. Acta tropica, 127(1), 69-74. https://doi.org/10.1016/j.actatropica.2013.03.007

Plasmodium falciparum transcripts contain long untranslated regions (UTR), with some of the longest in any eukaryote that uses monocistronic transcription. Owing to the extreme AT nucleotide bias within the intergenic regions that encode these UTR, a... Read More about Functional analysis of the 5′ untranslated region of the phosphoglutamase 2 transcript in Plasmodium falciparum.

The association of gout with sleep disorders: a cross-sectional study in primary care (2013)
Journal Article
Mallen, Roddy, & Muller. (2013). The association of gout with sleep disorders: a cross-sectional study in primary care. BMC Musculoskeletal Disorders, 119 -?. https://doi.org/10.1186/1471-2474-14-119

BACKGROUND: Both gout and sleep apnoea are associated with the metabolic syndrome. Hyperuricaemia is also prevalent in sleep apnoea syndrome. The objective of this study was to examine the association between gout and sleep apnoea and other sleep dis... Read More about The association of gout with sleep disorders: a cross-sectional study in primary care.

Touch in primary care consultations: qualitative investigation of doctors’ and patients’ perceptions (2013)
Journal Article
Cocksedge, S., George, B., Renwick, S., & Chew-Graham, C. A. (2013). Touch in primary care consultations: qualitative investigation of doctors’ and patients’ perceptions. British Journal of General Practice (BJGP), 63(609), e283-e290. https://doi.org/10.3399/bjgp13x665251

Background Good communication skills are integral to successful doctor–patient relationships. Communication may be verbal or non-verbal, and touch is a significant component, which has received little attention in the primary care literature. Touch m... Read More about Touch in primary care consultations: qualitative investigation of doctors’ and patients’ perceptions.

Low back pain among textile workers: a cross-sectional study (2013)
Journal Article
Paudyal, P., Ayres, J. G., Semple, S., & Macfarlane, G. J. (2013). Low back pain among textile workers: a cross-sectional study. Occupational Medicine, 63(2), 129-134. https://doi.org/10.1093/occmed/kqs231

Background: Low back pain (LBP) is one of the most prevalent occupational health problems in industrialized countries. Little is known about the epidemiology of LBP in developing countries. Aims: To determine the prevalence of LBP among Nepalese t... Read More about Low back pain among textile workers: a cross-sectional study.

Early intervention for psychosis in low- and middle-income countries needs a public health approach (2013)
Journal Article
Farooq, S. (2013). Early intervention for psychosis in low- and middle-income countries needs a public health approach. British Journal of Psychiatry, 202(3), 168-169. https://doi.org/10.1192/bjp.bp.112.113761

Early intervention in psychosis has significantly improved outcomes compared with standard treatment but it is considered as a luxury for low- and middle-income (LAMI) countries. However, a public health approach that is based on the principles of su... Read More about Early intervention for psychosis in low- and middle-income countries needs a public health approach.

The development and validation of an internet-based training package for the management of perineal trauma following childbirth: MaternityPEARLS (2013)
Journal Article
Mahmud, A., Kettle, C., Bick, D., Rowley, C., Rathod, T., Belcher, J., …Ismail, K. M. K. (2013). The development and validation of an internet-based training package for the management of perineal trauma following childbirth: MaternityPEARLS. Postgraduate Medical Journal, 89(1053), 382-389. https://doi.org/10.1136/postgradmedj-2012-131491

The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study (2013)
Journal Article
Wilkie, R., Tajar, A., & McBeth, J. (2013). The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study. PloS one, 8(3), e59858 - ?. https://doi.org/10.1371/journal.pone.0059858

OBJECTIVE: Chronic musculoskeletal pain is common in older adults but the nature of its relationship with ageing is unclear. The objective for this study was to test the hypothesis that the onset of widespread pain would be associated with a decrease... Read More about The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study.

ASSESSING HAND OSTEOARTHRITIS USING DIGITAL PHOTOGRAPHS IN A COMMUNITY-DWELLING POPULATION: RELIABILITY AND ASSOCIATIONS WITH RADIOGRAPHIC AND CLINICAL FEATURES (2013)
Journal Article
Marshall, M., Jonsson, H., Helgadottir, G. P., Nicholls, E., van der Windt, D., Myers, H., & Dziedzic, K. (2013). ASSESSING HAND OSTEOARTHRITIS USING DIGITAL PHOTOGRAPHS IN A COMMUNITY-DWELLING POPULATION: RELIABILITY AND ASSOCIATIONS WITH RADIOGRAPHIC AND CLINICAL FEATURES. Osteoarthritis and Cartilage, 21, S135-S135. https://doi.org/10.1016/j.joca.2013.02.286

Purpose: An atlas for grading hand osteoarthritis (OA) on photographs has been shown to be reliable and associated with clinical examination and radiographic features in a population of older adults (aged ≥69 years) from the AGES-Reykjavik study. The... Read More about ASSESSING HAND OSTEOARTHRITIS USING DIGITAL PHOTOGRAPHS IN A COMMUNITY-DWELLING POPULATION: RELIABILITY AND ASSOCIATIONS WITH RADIOGRAPHIC AND CLINICAL FEATURES.

Mobilising the experiential knowledge of clinicians, patients and carers for applied health-care research (2013)
Journal Article
Carter, P., Beech, R., Coxon, D., Thomas, M. J., & Jinks, C. (2013). Mobilising the experiential knowledge of clinicians, patients and carers for applied health-care research. Contemporary Social Science, 8(3), 307-320. https://doi.org/10.1080/21582041.2013.767468

This article demonstrates the benefits of combining various types of knowledge for applied health research. Funding is available for health research despite these being ‘austere times’ for public services and international policy shifts recognise the... Read More about Mobilising the experiential knowledge of clinicians, patients and carers for applied health-care research.

Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study (2013)
Journal Article
Kadam, U. T., Blagojevic, M., & Belcher, J. (2013). Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study. Journal of General Internal Medicine, 28(7), 943-949. https://doi.org/10.1007/s11606-013-2382-8

BACKGROUND: One hypothesis has posited whether abnormal lipid metabolism might be a causal factor in the pathogenesis of osteoarthritis (OA). Routine statin use in clinical practice provides the basis for a natural experiment in testing this hypothes... Read More about Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study.

Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB (2013)
Journal Article
Ali, N., Zhang, L., Taylor, S., Mironov, A., Urbé, S., & Woodman, P. (2013). Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB. Current Biology, 23(6), 453 - 461. https://doi.org/10.1016/j.cub.2013.02.033

Background Sorting ubiquitinated epidermal growth factor receptor (EGFR) to the intralumenal vesicles of the multivesicular body requires the coordinated action of several ESCRT complexes. A central question is how EGFR transits vectorially from ear... Read More about Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB.

Tips for GP trainees working in rheumatology (2013)
Journal Article
Welsh, V. (2013). Tips for GP trainees working in rheumatology. British Journal of General Practice (BJGP), 63(608), 164-165. https://doi.org/10.3399/bjgp13x664450

INTRODUCTION One in four people registered with a GP will consult for a musculoskeletal problem over a 12-month period; this accounts for one in seven GP consultations.1 Musculoskeletal conditions significantly impact daily life through pain, disabi... Read More about Tips for GP trainees working in rheumatology.

Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment (2013)
Journal Article
Balami, J. S., Fricker, R. A., & Chen, R. (2013). Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment. CNS & Neurological Disorders - Drug Targets, 12(2), 209 -219. https://doi.org/10.2174/1871527311312020007

No pharmacological intervention has been shown convincingly to improve neurological outcome in stroke patients after the brain tissue is infarcted. While conventional therapeutic strategies focus on preventing brain damage, stem cell treatment has th... Read More about Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment.

Operationalising unscheduled care policy: a qualitative study of healthcare professionals’ perspectives (2013)
Journal Article
Drinkwater, J., Salmon, P., Langer, S., Hunter, C., Stenhoff, A., Guthrie, E., & Chew-Graham, C. (2013). Operationalising unscheduled care policy: a qualitative study of healthcare professionals’ perspectives. British Journal of General Practice (BJGP), 63(608), e192-e199. https://doi.org/10.3399/bjgp13x664243

Background UK health policy aims to reduce the use of unscheduled care, by increasing proactive and preventative management of patients with long-term conditions in primary care. Aim The study explored healthcare professionals’ understanding of wh... Read More about Operationalising unscheduled care policy: a qualitative study of healthcare professionals’ perspectives.

Collaborative care for depression: a literature review and a model for implementation in developing countries (2013)
Journal Article
Farooq, S. (2013). Collaborative care for depression: a literature review and a model for implementation in developing countries. International Health, 5(1), 24-28. https://doi.org/10.1093/inthealth/ihs015

Depression will soon be the leading cause of disability in developing countries but effective treatments are not widely available. There is compelling evidence for the effectiveness and cost-effectiveness of the multicondition collaborative care (MCC... Read More about Collaborative care for depression: a literature review and a model for implementation in developing countries.

Slaying the dragon myth: an ethnographic study of receptionists in UK general practice (2013)
Journal Article
Hammond, J., Gravenhorst, K., Funnell, E., Beatty, S., Hibbert, D., Lamb, J., …Chew-Graham, C. A. (2013). Slaying the dragon myth: an ethnographic study of receptionists in UK general practice. British Journal of General Practice (BJGP), 63(608), e177-e184. https://doi.org/10.3399/bjgp13x664225

Background General practice receptionists fulfil an essential role in UK primary care, shaping patient access to health professionals. They are often portrayed as powerful ‘gatekeepers’. Existing literature and management initiatives advocate more tr... Read More about Slaying the dragon myth: an ethnographic study of receptionists in UK general practice.