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Higher education decolonisation: #Whose voices and their geographical locations? (2021)
Journal Article
Adefila, A., Teixeira, R. V., Morini, L., Garcia, M. L. T., Delboni, T. M. Z. G. F., Spolander, G., & Khalil-Babatunde, M. (2022). Higher education decolonisation: #Whose voices and their geographical locations?. Globalisation, Societies and Education, 20(3), 262-276. https://doi.org/10.1080/14767724.2021.1887724

Calls continue for the decolonisation of higher education (HE). Based on internationalisation debates, a research team from Africa, Europe and Latin America reviewed published decolonisation voices. Using bibliometric analysis and a conceptual review... Read More about Higher education decolonisation: #Whose voices and their geographical locations?.

Questions and answers on antithrombotic therapy and revascularization strategies in non-ST-elevation acute coronary syndrome (NSTE-ACS): a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. (2021)
Journal Article
Barbato, E., Mehilli, J., Sibbing, D., Siontis, G. C. M., Collet, J., Thiele, H., …Mamas, M. (2021). Questions and answers on antithrombotic therapy and revascularization strategies in non-ST-elevation acute coronary syndrome (NSTE-ACS): a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal, 1368 - 1378. https://doi.org/10.1093/eurheartj/ehaa601

Machine Learning-Augmented Propensity Score Analysis of Percutaneous Coronary Intervention in Over 30 Million Cancer and Non-cancer Patients. (2021)
Journal Article
Mamas. (2021). Machine Learning-Augmented Propensity Score Analysis of Percutaneous Coronary Intervention in Over 30 Million Cancer and Non-cancer Patients. Frontiers in Cardiovascular Medicine, -. https://doi.org/10.3389/fcvm.2021.620857

Background: It is unknown to what extent the clinical benefits of PCI outweigh the risks and costs in patients with vs. without cancer and within each cancer type. We performed the first known nationally representative propensity score analysis of PC... Read More about Machine Learning-Augmented Propensity Score Analysis of Percutaneous Coronary Intervention in Over 30 Million Cancer and Non-cancer Patients..

Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease ß Secretase, BACE1 (2021)
Journal Article
Mycroft-West, C. J., Devlin, A. J., Cooper, L. C., Guimond, S. E., Procter, P., Guerrini, M., …Skidmore, M. A. (2021). Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease ß Secretase, BACE1. Marine Drugs, 19(4), 203 -203. https://doi.org/10.3390/md19040203

Only palliative therapeutic options exist for the treatment of Alzheimer’s Disease; no new successful drug candidates have been developed in over 15 years. The widely used clinical anticoagulant heparin has been reported to exert beneficial effects t... Read More about Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease ß Secretase, BACE1.

Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China (2021)
Journal Article
Lu, L., Chen, Y., Cai, Y., Chen, T., Huang, Y., Meng, H., & Yu, D. (2021). Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China. Obesity Research and Clinical Practice, 15(3), 216-220. https://doi.org/10.1016/j.orcp.2021.03.011

Background Relationship between physical activity and fasting glucose in people with abnormal glucose metabolism is not well-known. This study was to investigate dose–response association between physical activity (PAT) and fasting glucose from two... Read More about Physical activity and fasting glucose in adults with abnormal glucose metabolism: Findings from two independent cross-sectional studies in China.

Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes. (2021)
Journal Article
Mamas. (2021). Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes. Journal of Interventional Cardiology, https://doi.org/10.1155/2021/6654515

Background: While thinner struts are associated with improved clinical outcomes in bare-metal stents (BMS), reducing strut thickness may affect drug delivery from drug-eluting stents (DES) and there are limited data comparing otherwise similar thin a... Read More about Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes..

Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF. (2021)
Journal Article
Pedro Ferreira, J., Verdonschot, J., Wang, P., Pizard, A., Collier, T., Ahmed, F. Z., …Zannad, F. (2021). Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF. JACC: Heart Failure, 268 - 277. https://doi.org/10.1016/j.jchf.2020.11.010

OBJECTIVES: This study sought to further understand the mechanisms underlying effect of spironolactone and assessed its impact on multiple plasma protein biomarkers and their respective underlying biologic pathways. BACKGROUND: In addition to their b... Read More about Proteomic and Mechanistic Analysis of Spironolactone in Patients at Risk for HF..

Location of death among patients presenting with cardiovascular disease to the emergency department in the United states. (2021)
Journal Article
Mamas. (2021). Location of death among patients presenting with cardiovascular disease to the emergency department in the United states. https://doi.org/10.1111/ijcp.13798

BACKGROUND: In-hospital deaths are an important outcome and little is known about deaths in the emergency department (ED). Among patients who died of cardiovascular diseases (CVD), we assessed causes of death, temporal trends and the relative distrib... Read More about Location of death among patients presenting with cardiovascular disease to the emergency department in the United states..

Trends, Outcomes, and Predictive Score For Emergency Coronary Artery Bypass Graft Surgery After Elective Percutaneous Coronary Intervention (from a Nationwide Dataset). (2021)
Journal Article
Mamas, M. (2021). Trends, Outcomes, and Predictive Score For Emergency Coronary Artery Bypass Graft Surgery After Elective Percutaneous Coronary Intervention (from a Nationwide Dataset). https://doi.org/10.1016/j.amjcard.2020.12.060

The temporal trends and preprocedural predictors of emergency coronary artery bypass graft surgery (ECABG) after elective percutaneous coronary intervention (PCI) in the contemporary era are largely unknown. From January 2003 to December 2014 electiv... Read More about Trends, Outcomes, and Predictive Score For Emergency Coronary Artery Bypass Graft Surgery After Elective Percutaneous Coronary Intervention (from a Nationwide Dataset)..

Hearing the unheard voice-puberty experiences of young Pakistani men: A qualitative study (2021)
Journal Article
Shivji. (2021). Hearing the unheard voice-puberty experiences of young Pakistani men: A qualitative study. Journal of Adolescence, 36 - 47. https://doi.org/10.1016/j.adolescence.2021.02.003

Introduction Puberty experiences of male adolescents can have significant impacts on physical and psychological health outcomes. This qualitative study explored the puberty experiences of young males in Pakistan, as there are limited accounts of wha... Read More about Hearing the unheard voice-puberty experiences of young Pakistani men: A qualitative study.

Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial (2021)
Journal Article
Chesterton, L. S., Thomas, M. J., Hendry, G., Chen, Y., Goddin, D., Halliday, N., …Roddy, E. (2021). Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial. Pilot and Feasibility Studies, 7, Article 92. https://doi.org/10.1186/s40814-021-00808-0

Plantar heel pain (PHP) is common and impacts negatively on physical function and quality of life. Initial treatment usually comprises analgesia and self-management advice (SMA), with referral to a physiotherapist or podiatrist recommended only when... Read More about Self-management advice, exercise and foot orthoses for plantar heel pain: the TREADON pilot and feasibility randomised trial.

Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care. (2021)
Journal Article
Mallen. (2021). Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care. British Journal of General Practice (BJGP), e296-e302. https://doi.org/10.3399/bjgp21X714281

BACKGROUND: In 2011, National Institute for Health and Care Excellence (NICE) guidelines recommended the routine use of out-of-office blood pressure (BP) monitoring for the diagnosis of hypertension. These changes were predicted to reduce unnecessary... Read More about Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care..

Racial, ethnic and socioeconomic disparities in patients undergoing left atrial appendage closure (2021)
Journal Article
Sparrow, R., Sanjoy, S., Choi, Y., Elgendy, I. Y., Jneid, H., Villablanca, P. A., …Bagur, R. (2021). Racial, ethnic and socioeconomic disparities in patients undergoing left atrial appendage closure. Heart, 107(24), 1946-1955. https://doi.org/10.1136/heartjnl-2020-318650

OBJECTIVE: This manuscript aims to explore the impact of race/ethnicity and socioeconomic status on in-hospital complication rates after left atrial appendage closure (LAAC). METHODS: The US National Inpatient Sample was used to identify hospitalisat... Read More about Racial, ethnic and socioeconomic disparities in patients undergoing left atrial appendage closure.

Radial First in ST-Segment-Elevation Myocardial Infarction (2021)
Journal Article
Jolly, S. S., & Nolan, J. (2021). Radial First in ST-Segment-Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 14(3), Article ARTN e010595. https://doi.org/10.1161/CIRCINTERVENTIONS.121.010595

As young interventionalists, we recall randomizing patients with ST-segment–elevation myocardial infarction (STEMI) into studies such as the RIVAL trial (the Radial Versus Femoral Access for Coronary Angiography and Intervention) and struggling with... Read More about Radial First in ST-Segment-Elevation Myocardial Infarction.

Identifying predictors of ventral hernia recurrence: systematic review and meta-analysis (2021)
Journal Article
Parker, S. G., Mallett, S., Quinn, L., Wood, C. P. J., Boulton, R. W., Jamshaid, S., …Halligan, S. (2021). Identifying predictors of ventral hernia recurrence: systematic review and meta-analysis. BJS Open, 5(2), 1-9. https://doi.org/10.1093/bjsopen/zraa071

BACKGROUND: Ventra hernias are increasing in prevalence and many recur despite attempted repair. To date, much of the literature is underpowered and divergent. As a result there is limited high quality evidence to inform surgeons succinctly which per... Read More about Identifying predictors of ventral hernia recurrence: systematic review and meta-analysis.

Toward a More Nuanced Interpretation of Statistical Significance in Biomedical Research (2021)
Journal Article
Bajpai, R., & Chaturvedi, H. K. (2021). Toward a More Nuanced Interpretation of Statistical Significance in Biomedical Research. Asian Journal of Oncology, 07, 049-051. https://doi.org/10.1055/s-0041-1727066

Editorial Statistical significance is the bedrock of evidence-based medicine, crucial for decision-making and framing biomedical science policies. The emergence of complex data in many disciplines, resulting from the analysis of large datasets, has... Read More about Toward a More Nuanced Interpretation of Statistical Significance in Biomedical Research.

Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study). (2021)
Journal Article
Van Der Windt. (2021). Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study). BMJ Open, e050101 - ?. https://doi.org/10.1136/bmjopen-2021-050101

INTRODUCTION: Shoulder pain is common and the prognosis is often unfavourable. Dutch guidelines on the treatment of shoulder pain in primary care recommend a corticosteroid injection or a referral to exercise therapy, if initial pain management fails... Read More about Clinical and cost effectiveness of a corticosteroid injection versus exercise therapy for shoulder pain in general practice: protocol for a randomised controlled trial (SIX Study)..