All Outputs (575)

Outcomes of rotational atherectomy versus orbital atherectomy for the treatment of heavily calcified coronary stenosis: A systematic review and meta-analysis. (2021)
Journal Article
Mamas. (2021). Outcomes of rotational atherectomy versus orbital atherectomy for the treatment of heavily calcified coronary stenosis: A systematic review and meta-analysis. Catheterization and Cardiovascular Interventions, 884 - 892. https://doi.org/10.1002/ccd.29430

INTRODUCTION: The optimal approach to deal with severe coronary artery calcification (CAC) during percutaneous coronary intervention (PCI) remains ill-defined. METHODS: We conducted an electronic database search of all published studies comparing Orb... Read More about Outcomes of rotational atherectomy versus orbital atherectomy for the treatment of heavily calcified coronary stenosis: A systematic review and meta-analysis..

Association of SARS-CoV-2 Infection With Psychological Distress, Psychotropic Prescribing, Fatigue, and Sleep Problems Among UK Primary Care Patients. (2021)
Journal Article
Chew-Graham. (2021). Association of SARS-CoV-2 Infection With Psychological Distress, Psychotropic Prescribing, Fatigue, and Sleep Problems Among UK Primary Care Patients. Jama Network Open, e2134803 - ?. https://doi.org/10.1001/jamanetworkopen.2021.34803

Importance: Infection with SARS-CoV-2 is associated with fatigue and sleep problems long after the acute phase of COVID-19. In addition, there are concerns of SARS-CoV-2 infection causing psychiatric illness; however, evidence of a direct effect is i... Read More about Association of SARS-CoV-2 Infection With Psychological Distress, Psychotropic Prescribing, Fatigue, and Sleep Problems Among UK Primary Care Patients..

Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability (2021)
Journal Article
Davies. (2021). Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 533-541. https://doi.org/10.1177/08968608211049882

Background: In Europe, the number of elderly end-stage kidney disease patients is increasing. Few of those patients receive peritoneal dialysis (PD), as many cannot perform PD autonomously. Assisted PD programmes are available in most European coun... Read More about Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability.

Supporting patients with long COVID return to work. (2021)
Journal Article
Chew-Graham. (2021). Supporting patients with long COVID return to work. British Journal of General Practice (BJGP), 508 - 509. https://doi.org/10.3399/bjgp21X717533

Post-COVID-19 syndrome, often called ‘long COVID’ refers to signs and/or symptoms that develop following COVID-19 infection, which continue for more than 12 weeks and are not explained by an alternative diagnosis.1 Long COVID presents with clusters o... Read More about Supporting patients with long COVID return to work..

Relation of High-Sensitivity Troponin to 1 Year Mortality in 20,000 Consecutive Hospital Patients Undergoing a Blood Test for Any Reason. (2021)
Journal Article
Hinton, J., Mariathas, M., Gabara, L., Allan, R., Nicholas, Z., Shing Kwok, C., …Curzen, N. (2021). Relation of High-Sensitivity Troponin to 1 Year Mortality in 20,000 Consecutive Hospital Patients Undergoing a Blood Test for Any Reason. American Journal of Cardiology, 124 - 131. https://doi.org/10.1016/j.amjcard.2021.07.050

This was an observational study of the 1-year outcomes of the 20,000 patients included in the original CHARIOT study. The aim of the study was to assess the association between high sensitivity troponin I (hs-cTnI) concentration and 1 year mortality... Read More about Relation of High-Sensitivity Troponin to 1 Year Mortality in 20,000 Consecutive Hospital Patients Undergoing a Blood Test for Any Reason..

Shock index predicts up to 90-day mortality risk after intracerebral haemorrhage. (2021)
Journal Article
Pana, T. A., Quinn, T. J., Perdomo-Lampignano, J. A., Szlachetka, W. A., Knoery, C., Mamas, M. A., …Collaborators, V. (2021). Shock index predicts up to 90-day mortality risk after intracerebral haemorrhage. Clinical Neurology and Neurosurgery, 106994 - ?. https://doi.org/10.1016/j.clineuro.2021.106994

BACKGROUND: Shock index (SI - heart rate/systolic blood pressure) has been studied as a measure of haemodynamic status. We aimed to determine whether SI measures within 72 h of admission were associated with adverse outcomes in intracerebral haemorrh... Read More about Shock index predicts up to 90-day mortality risk after intracerebral haemorrhage..

Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019. (2021)
Journal Article
Mamas, M. (2021). Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019. International Journal of Clinical Practice, e14841 - ?. https://doi.org/10.1111/ijcp.14841

BACKGROUND: Cancer is the second most common cause of death globally after cardiovascular disease, and cancer patients are at an increased risk of CV death. This recognition has led to publication of cardio-oncological guidelines and to the widesprea... Read More about Trends in cardiovascular mortality of cancer patients in the US over two decades 1999-2019..

Impact of malignancy on In-hospital mortality, stratified by the cause of admission: An analysis of 67 million patients from the National Inpatient Sample. (2021)
Journal Article
Mamas. (2021). Impact of malignancy on In-hospital mortality, stratified by the cause of admission: An analysis of 67 million patients from the National Inpatient Sample. International Journal of Clinical Practice, e14758 - ?. https://doi.org/10.1111/ijcp.14758

OBJECTIVE: To describe the patient characteristics and the reason for admission of patients with malignancy by malignancy, and to study mortality rates for the different causes of admissions among the different types of cancer. PATIENTS AND METHODS:... Read More about Impact of malignancy on In-hospital mortality, stratified by the cause of admission: An analysis of 67 million patients from the National Inpatient Sample..

Children’s pictures of COVID-19 and measures to mitigate its spread: an international qualitative study (2021)
Journal Article
Protheroe. (2021). Children’s pictures of COVID-19 and measures to mitigate its spread: an international qualitative study. Health Education Journal, 811-832. https://doi.org/10.1177/00178969211019459

Objectives: To gain insight into children’s health-related knowledge and understanding of SARS-CoV2 and measures adopted to mitigate transmission. Design: A child-centred qualitative creative element, embedded in an online mixed method survey of ch... Read More about Children’s pictures of COVID-19 and measures to mitigate its spread: an international qualitative study.

Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic (2021)
Journal Article
Shoaib, A., Van Spall, H. G. C., Wu, J., Cleland, J. G. F., McDonagh, T. A., Rashid, M., …Mamas, M. A. (2021). Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal - Quality of Care and Clinical Outcomes, 7(4), 378-387. https://doi.org/10.1093/ehjqcco/qcab040

Aims We hypothesized that a decline in admissions with heart failure during COVID-19 pandemic would lead to a reciprocal rise in mortality for patients with heart failure in the community. Methods and results We used National Heart Failure Audit d... Read More about Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic.

Patient satisfaction with the first contact physiotherapy service: Results from the national evaluation survey (2021)
Journal Article
Stynes, Wood, L., Bishop, A., & Goodwin, R. (2022). Patient satisfaction with the first contact physiotherapy service: Results from the national evaluation survey. Musculoskeletal Care, 20(2), 363-370. https://doi.org/10.1002/msc.1599

BACKGROUND: Musculoskeletal (MSK) First Contact Physiotherapists (FCPs) are diagnostic clinicians able to assess and manage undifferentiated and undiagnosed MSK presentations. The FCP role in primary care has been introduced to allow patients with MS... Read More about Patient satisfaction with the first contact physiotherapy service: Results from the national evaluation survey.

Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk. (2021)
Journal Article
Mamas, M. (2021). Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk. https://doi.org/10.1056/NEJMoa2108749

BACKGROUND: The appropriate duration of dual antiplatelet therapy in patients at high risk for bleeding after the implantation of a drug-eluting coronary stent remains unclear. METHODS: One month after they had undergone implantation of a biodegradab... Read More about Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk..

Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest. (2021)
Journal Article
Mamas, M., & Rashid, M. (2021). Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest. Resuscitation, 327-334. https://doi.org/10.1016/j.resuscitation.2021.10.031

OBJECTIVES: We aimed to identify whether the availability of catheter laboratory affects clinical outcomes of out-of-hospital cardiac arrest (OHCA) complicating myocardial infarction (AMI). METHODS: Patients admitted with a diagnosis of AMI and OHCA... Read More about Impact of availability of catheter laboratory facilities on management and outcomes of acute myocardial infarction presenting with out of hospital cardiac arrest..

When I say... Social (2021)
Journal Article
Guckian, J., & Rees, E. L. (2022). When I say... Social. Medical Education, 56(1), 25-26. https://doi.org/10.1111/medu.14682

When the authors say "social" within medical education, they mean learning and working cultures that foster companionship, distribute capital, and facilitate communication. This piece discusses the impact of imbalance across these factors.

Pivot to online learning for adapting or continuing workplace-based clinical learning in medical education following the COVID-19 pandemic: A BEME systematic review (2021)
Journal Article
Rees. (2021). Pivot to online learning for adapting or continuing workplace-based clinical learning in medical education following the COVID-19 pandemic: A BEME systematic review. Medical Teacher, https://doi.org/10.1080/0142159X.2021.1992372

Background The novel coronavirus disease (COVID-19) was declared a pandemic in March 2020, which necessitated adaptations to medical education. This systematic review synthesises published reports of medical educational developments and innovations... Read More about Pivot to online learning for adapting or continuing workplace-based clinical learning in medical education following the COVID-19 pandemic: A BEME systematic review.

What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study (2021)
Journal Article
Weddell, J., Hider, S., Mallen, C., & Muller, S. (2022). What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study. Rheumatology International, 285-290. https://doi.org/10.1007/s00296-021-05036-6

Polymyalgia rheumatica (PMR) is common. The mainstay of treatment, glucocorticoids, are associated with significant adverse effects and many patients remain on high doses for a number of years. Little is known about the use of other, non-pharmacologi... Read More about What non-pharmacological treatments do people with polymyalgia rheumatica try: results from the PMR Cohort Study.

Osteoarthritis year in review 2021: epidemiology & therapy (2021)
Journal Article
Quicke, J. G., Conaghan, P. G., Corp, N., & Peat, G. (2022). Osteoarthritis year in review 2021: epidemiology & therapy. Osteoarthritis and Cartilage, 30(2), 196-206. https://doi.org/10.1016/j.joca.2021.10.003

This "Year in review" presents a selection of research themes and individual studies from the clinical osteoarthritis (OA) field (epidemiology and therapy) and includes noteworthy descriptive, analytical-observational, and intervention studies. The e... Read More about Osteoarthritis year in review 2021: epidemiology & therapy.

Readmission after index hospital discharge among patients with COVID-19: Protocol for a systematic review and meta-analysis (2021)
Journal Article
AlSayegh, A., Gassan, A. A., Bajpai, R. C., Muller, S., Welsh, V., Kwok, C. S., & Mallen, C. D. (2021). Readmission after index hospital discharge among patients with COVID-19: Protocol for a systematic review and meta-analysis. Health Science Reports, 4(4), Article ARTN e417. https://doi.org/10.1002/hsr2.417

Background and Aims: Hospital readmissions among COVID-19 patients have increased the load on the healthcare systems and added more pressure to hospital capacity. This affects the ability to accommodate newly diagnosed COVID-19 patients and other non... Read More about Readmission after index hospital discharge among patients with COVID-19: Protocol for a systematic review and meta-analysis.

Support needs and barriers to accessing support: Baseline results of a mixed-methods national survey of people bereaved during the COVID-19 pandemic. (2021)
Journal Article
(2021). Support needs and barriers to accessing support: Baseline results of a mixed-methods national survey of people bereaved during the COVID-19 pandemic

BACKGROUND: The COVID-19 pandemic is a mass bereavement event which has profoundly disrupted grief experiences. Understanding support needs and access to support among people bereaved at this time is crucial to ensuring appropriate bereavement suppor... Read More about Support needs and barriers to accessing support: Baseline results of a mixed-methods national survey of people bereaved during the COVID-19 pandemic..

AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. (2021)
Journal Article
Morelle, J., Marechal, C., Yu, Z., Debaix, H., Corre, T., Lambie, M., …Devuyst, O. (2021). AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. New England Journal of Medicine, 385, 1570 - 1580. https://doi.org/10.1056/NEJMoa2034279

BACKGROUND: Variability in ultrafiltration influences prescriptions and outcomes in patients with kidney failure who are treated with peritoneal dialysis. Variants in AQP1, the gene that encodes the archetypal water channel aquaporin-1, may contribut... Read More about AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis..