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All Outputs (4695)

Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum (2024)
Journal Article
Scott, I. C., Daud, N., Bailey, J., Twohig, H., Hider, S. L., Mallen, C. D., …Muller, S. (in press). Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum. BMC Medicine, 22(1), 575. https://doi.org/10.1186/s12916-024-03774-5

Background: Gabapentinoids are increasingly prescribed in inflammatory arthritis (IA), despite no trial evidence for efficacy at managing pain in this population. Observational studies in non-IA populations suggest gabapentinoids are associated with... Read More about Gabapentinoid use and the risk of fractures in patients with inflammatory arthritis: nested case–control study in the Clinical Practice Research Datalink Aurum.

Medical ambivalence and Long Covid: The disconnects, entanglements, and productivities shaping ethnic minority experiences in the UK (2024)
Journal Article
Ridge, D. T., Broom, A., Alwan, N. A., Chew-Graham, C. A., Smyth, N., Gopal, D., …Begum, S. (2024). Medical ambivalence and Long Covid: The disconnects, entanglements, and productivities shaping ethnic minority experiences in the UK. Social Science and Medicine, Article 117603. https://doi.org/10.1016/j.socscimed.2024.117603

Structural violence - related to ‘isms’ like racism, sexism, and ableism – pertains to the ways in which social institutions harm certain groups. Such violence is critical to institutional indifference to the plight of ethnic minori... Read More about Medical ambivalence and Long Covid: The disconnects, entanglements, and productivities shaping ethnic minority experiences in the UK.

The International Society of Nephrology collaborative quality framework to support safe and effective dialysis provision in resource-challenged settings. (2024)
Journal Article
Davies, S., Naicker, S., Liew, A., Vachharajani, T., Pecoits-Filho, R., Jha, V., …Harris, D. C. (2024). The International Society of Nephrology collaborative quality framework to support safe and effective dialysis provision in resource-challenged settings. Kidney International Reports, https://doi.org/10.1016/j.ekir.2024.11.1366

Global under-provision of affordable dialysis results in inequitable access to safe and effective treatment. Identified as a key priority for the International Society of Nephrology (ISN) Kidney Failure Strategy, the need was identified for a dialysi... Read More about The International Society of Nephrology collaborative quality framework to support safe and effective dialysis provision in resource-challenged settings..

Comparative risk of type 2 diabetes development between women with gestational diabetes and women with impaired glucose tolerance over two decades: a multiethnic prospective cohort in New Zealand (2024)
Journal Article
Yu, D., Fu, H., Zhao, Z., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (2024). Comparative risk of type 2 diabetes development between women with gestational diabetes and women with impaired glucose tolerance over two decades: a multiethnic prospective cohort in New Zealand. BMJ Open Diabetes Research and Care, 12(6), https://doi.org/10.1136/bmjdrc-2024-004210

Introduction: To evaluate the long-term risk of developing type 2 diabetes (T2D) among women with a history of gestational diabetes mellitus (GDM) compared with those with impaired glucose tolerance (IGT). Research design and methods: Using data from... Read More about Comparative risk of type 2 diabetes development between women with gestational diabetes and women with impaired glucose tolerance over two decades: a multiethnic prospective cohort in New Zealand.

Neural Cell Interactions with a Surgical Grade Biomaterial Using a Simulated Injury in Brain Organotypic Slices (2024)
Journal Article
Wiseman, J. P., & Chari, D. M. (in press). Neural Cell Interactions with a Surgical Grade Biomaterial Using a Simulated Injury in Brain Organotypic Slices. Journal of Functional Biomaterials, 15(12), Article 362. https://doi.org/10.3390/jfb15120362

Tissue engineering research for neurological applications has demonstrated that biomaterial-based structural bridges present a promising approach for promoting regeneration. This is particularly relevant for penetrating traumatic brain injuries, wher... Read More about Neural Cell Interactions with a Surgical Grade Biomaterial Using a Simulated Injury in Brain Organotypic Slices.

Prediction of Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer From Gene Expression Profiling Using Cox-Boost Regression Model (2024)
Journal Article
Hamidi, O., Amini, P., Tapak, L., Zohrab Beigi, Y., Afshar, S., & Dinu, I. (in press). Prediction of Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer From Gene Expression Profiling Using Cox-Boost Regression Model. Cancer Informatics, 23, https://doi.org/10.1177/11769351241297493

Backgrounds:: Distant metastasis in breast cancer patients contributes to increased breast cancer mortality, highlighting the urgent need for effective predictive strategies. Understanding metastasis mechanisms and identifying relevant biomarkers are... Read More about Prediction of Distant Metastasis of Lymph-Node-Negative Primary Breast Cancer From Gene Expression Profiling Using Cox-Boost Regression Model.

Understanding and improving the quality of primary care for people in prison: a mixed-methods study (2024)
Journal Article
Bellass, S., Canvin, K., Farragher, T., McLintock, K., Wright, N., Hearty, P., …Sheard, L. (2024). Understanding and improving the quality of primary care for people in prison: a mixed-methods study. Health and Social Care Delivery Research, 12(46), https://doi.org/10.3310/GRFV4068

Background
People in prison are generally in poorer health than their peers in the community, often living with chronic illness and multimorbidity. Healthcare research in prisons has largely focused on specific problems, such as substance use; less... Read More about Understanding and improving the quality of primary care for people in prison: a mixed-methods study.

Everyday Living with Osteoarthritis in the Global South: A qualitative focus group inquiry in Nigeria. (2024)
Journal Article
Owoyemi, T., Alonge, I., Adetunji, O., Ogbu, E., Ogunbanjo, A., White, S., …Dziedzic, K. (2024). Everyday Living with Osteoarthritis in the Global South: A qualitative focus group inquiry in Nigeria. Osteoarthritis and Cartilage Open, Article 100555. https://doi.org/10.1016/j.ocarto.2024.100555

Objective
Africa contributes significantly to the increasing global prevalence (>37%), unmet need and treatment burden for people with osteoarthritis. Despite this, little research has examined the expressed needs of patients with osteoarthritis (OA... Read More about Everyday Living with Osteoarthritis in the Global South: A qualitative focus group inquiry in Nigeria..

Effects of employees living with an ‘arthritis’ on sickness absence and transitions out of employment: a comparative observational study in the UK (2024)
Journal Article
Whittaker, W., Higgerson, J., Eden, M., Payne, K., Wilkie, R., & Verstappen, S. M. (2024). Effects of employees living with an ‘arthritis’ on sickness absence and transitions out of employment: a comparative observational study in the UK. RMD Open, 10(4), 1-13. https://doi.org/10.1136/rmdopen-2024-004817

Purpose: To assess sickness absence and transitions from employment for employees with arthritis compared with employees without arthritis over time. Methods: We use 10 waves of the UK Household Longitudinal Survey (2009–2019). The sample (n=38 928)... Read More about Effects of employees living with an ‘arthritis’ on sickness absence and transitions out of employment: a comparative observational study in the UK.

Enhancing comparability in early child development assessment with the D-score (2024)
Journal Article
van Buuren, S., Eekhout, I., McCray, G., Lancaster, G. A., Waldman, M. R., McCoy, D. C., …Black, M. M. (in press). Enhancing comparability in early child development assessment with the D-score. International Journal of Behavioral Development, 17. https://doi.org/10.1177/01650254241294033

The lack of a valid and interpretable score to track early child development over time is a primary reason for neglecting child development in policymaking. Many instruments exist, but there is no accepted method for comparing their scores across dif... Read More about Enhancing comparability in early child development assessment with the D-score.

Healthcare utilisation of 282,080 individuals with long COVID over two years: a multiple matched control, longitudinal cohort analysis. (2024)
Journal Article
Mu, Y., Dashtban, A., Mizani, M. A., Tomlinson, C., Mohamed, M., Ashworth, M., …Banerjee, A. (in press). Healthcare utilisation of 282,080 individuals with long COVID over two years: a multiple matched control, longitudinal cohort analysis. Journal of the Royal Society of Medicine, 13. https://doi.org/10.1177/01410768241288345

ObjectivesTo investigate healthcare utilisation and cost in individuals with long COVID (LC) at population level.DesignCase-control cohort analysis with multiple age-, sex-, ethnicity-, deprivation-, region- and comorbidity-matched control groups: (1... Read More about Healthcare utilisation of 282,080 individuals with long COVID over two years: a multiple matched control, longitudinal cohort analysis..

Sex differences in myocardial infarction care and outcomes: a longitudinal Scottish National Data-Linkage Study (2024)
Journal Article
Pana, T. A., Mamas, M. A., Myint, P. K., & Dawson, D. K. (in press). Sex differences in myocardial infarction care and outcomes: a longitudinal Scottish National Data-Linkage Study. European Journal of Preventive Cardiology, https://doi.org/10.1093/eurjpc/zwae333

Aims We investigate sex disparities in management and outcomes of myocardial infarction (MI) in contemporary practice in Scotland. Methods and results This was a longitudinal cohort study including all MI admissions aged 45-80 years across Scotland b... Read More about Sex differences in myocardial infarction care and outcomes: a longitudinal Scottish National Data-Linkage Study.

Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: A population-based cohort study (2024)
Journal Article
Ho, F. K., Dale, C., Mizani, M. A., Bolton, T., Pearson, E. R., Valabhji, J., …Sattar, N. (in press). Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: A population-based cohort study. PLoS Medicine, 21(11), Article e1004485. https://doi.org/10.1371/journal.pmed.1004485

Background: This study estimated to what extent the number of measurements of cardiometabolic risk factors (e.g., blood pressure, cholesterol, glycated haemoglobin) were impacted by the COVID-19 pandemic and whether these have recovered to expected l... Read More about Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: A population-based cohort study.

The future of peritoneal dialysis (2024)
Journal Article
Davies, S. (in press). The future of peritoneal dialysis. Clinical Kidney Journal, 17(Supplement_2), 9-18. https://doi.org/10.1093/ckj/sfae277

Peritoneal dialysis (PD), long established as the leading form of home dialysis, has comparatively good 5-year outcomes and cost-utility analyses have consistently demonstrated benefits to both patients and payers. Future improvements should still be... Read More about The future of peritoneal dialysis.

Identifying Key Moments in Type 2 Diabetes Management: A Qualitative Study of the Experiences of People With Type 2 Diabetes and Diabetes Health Coaches (2024)
Journal Article
Joyce, J. B., Newbert, C., Guess, N., Fryer, K., Mitchell, C. A., Bespala, L., …Albury, C. (2024). Identifying Key Moments in Type 2 Diabetes Management: A Qualitative Study of the Experiences of People With Type 2 Diabetes and Diabetes Health Coaches. Health Expectations, 27(6), Article e70108. https://doi.org/10.1111/hex.70108

Objective: For people with type 2 diabetes who are overweight, weight loss increases the likelihood of achieving diabetes remission. The aim here was to draw on the experiences of people living with type 2 diabetes and coaches who deliver type 2 diab... Read More about Identifying Key Moments in Type 2 Diabetes Management: A Qualitative Study of the Experiences of People With Type 2 Diabetes and Diabetes Health Coaches.

Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope (2024)
Journal Article
Scott, I. C., Babatunde, O., Barker, C., Beesley, R., Beesley, R., Birkinshaw, H., …Shenker, N. G. (in press). Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(4), Article rkae128. https://doi.org/10.1093/rap/rkae128

Lay Summary: What does this mean for patients? Inflammatory arthritis includes conditions causing swollen and painful joints. The main types are rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis and juvenile idiopathic arthritis. It... Read More about Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope.

A multidisciplinary weight management intervention for adults with severe mental illness in forensic psychiatric inpatient services (Motiv8): a single blind cluster-randomised wait-list controlled feasibility trial (2024)
Journal Article
Carney, R., Law, H., El-Metaal, H., Hann, M., Shields, G., Savage, S., …Parker, S. (2024). A multidisciplinary weight management intervention for adults with severe mental illness in forensic psychiatric inpatient services (Motiv8): a single blind cluster-randomised wait-list controlled feasibility trial. Frontiers in Psychiatry, 15, 1-13. https://doi.org/10.3389/fpsyt.2024.1457864

Background: People with severe mental illness experience physical health inequalities and a 15–20-year premature mortality rate. Forensic inpatients are particularly affected by restrictions on movement, long admissions, and obesogenic/sedative psych... Read More about A multidisciplinary weight management intervention for adults with severe mental illness in forensic psychiatric inpatient services (Motiv8): a single blind cluster-randomised wait-list controlled feasibility trial.

Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. (2024)
Journal Article
Fletcher, R. A., Rockenschaub, P., Neuen, B. L., Walter, I. J., Conrad, N., Mizani, M. A., …Wood, A. M. (2024). Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. The Lancet, 9(11), e871-e885. https://doi.org/10.1016/S2468-2667%2824%2900215-9

Heart failure is common, complex, and often associated with coexisting chronic medical conditions and a high mortality. We aimed to assess the epidemiology of people admitted to hospital with heart failure with reduced ejection fraction (HFrEF) and h... Read More about Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records..