All Outputs (17)

Development and application of multivariate meta-analysis in medical research: borrowing strength across multiple correlated outcomes (2019)
Thesis
Hattle, M. S. M. (2019). Development and application of multivariate meta-analysis in medical research: borrowing strength across multiple correlated outcomes. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/415208

Multivariate meta-analysis methods combine effect estimates for multiple correlated outcomes (such as systolic and diastolic blood pressure) from independent studies, utilising their between-study and within-study correlations. In contrast, a univari... Read More about Development and application of multivariate meta-analysis in medical research: borrowing strength across multiple correlated outcomes.

Understanding self-harm behaviour in older adults: a systematic review and qualitative study (2019)
Thesis
Troya Bermeo, M. I. (2019). Understanding self-harm behaviour in older adults: a systematic review and qualitative study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/415218

Two worldwide challenges served as a drive for this research: the reality of an ageing population and the identified need of supporting people who self-harm. Addressing self-harm has been increasingly prioritised due to its social, economic and healt... Read More about Understanding self-harm behaviour in older adults: a systematic review and qualitative study.

Investigating the presence and impact of competing events on prognostic model research (2019)
Thesis
Teece, L. (2019). Investigating the presence and impact of competing events on prognostic model research. (Thesis). Keele University

Prognostic models are used to predict an individual’s future health outcomes, including the risk of disease progression and the development of further complications. The statistical methodology used to develop these models is often naïve to the prese... Read More about Investigating the presence and impact of competing events on prognostic model research.

Comparison of cough plates and cough swabs for detecting respiratory pathogens in non-expectorating children with cystic fibrosis (2019)
Thesis
Kemball, B. M. H. (2019). Comparison of cough plates and cough swabs for detecting respiratory pathogens in non-expectorating children with cystic fibrosis. (Thesis). Keele University

Background Cystic fibrosis (CF) is an autosomal recessive, multisystem disorder affecting ion transportation across epithelial membranes. Respiratory complications are the leading cause of morbidity and mortality and CF lung disease is characterised... Read More about Comparison of cough plates and cough swabs for detecting respiratory pathogens in non-expectorating children with cystic fibrosis.

A mixed methods study exploring organisational factors influencing the development of services for people with dementia in English hospices (2019)
Thesis
Hodges, E. (2019). A mixed methods study exploring organisational factors influencing the development of services for people with dementia in English hospices. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414942

Hospices are being challenged by changing demographics in the UK population. Originating from a response to cancer, hospices have struggled to diversify. As the population ages, dementia creates a particular challenge. A report by the Alzheimer’s Soc... Read More about A mixed methods study exploring organisational factors influencing the development of services for people with dementia in English hospices.

An epidemiological investigation into the incidence, prevalence, treatment and comorbidities associated with polymyalgia rheumatica in the United Kingdom 1990-2015 (2019)
Thesis
Partington, R. J. (2019). An epidemiological investigation into the incidence, prevalence, treatment and comorbidities associated with polymyalgia rheumatica in the United Kingdom 1990-2015. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414978

Background Polymyalgia rheumatica (PMR) is a common inflammatory rheumatic disease that affects older people. It can cause stiffness, severe pain and significant impairment to daily activities. Glucocorticoids (GCs) remain the mainstay of treatment... Read More about An epidemiological investigation into the incidence, prevalence, treatment and comorbidities associated with polymyalgia rheumatica in the United Kingdom 1990-2015.

Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes (2019)
Thesis
Rashid, M. (2019). Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414984

Non-elevation acute myocardial infarction (NSTEMI) is one of the commonest phenotype of acute coronary syndrome (ACS) and associated with significant morbidity and mortality at the short and long term. An invasive strategy in the form of coronary ang... Read More about Use of invasive strategies in the management of non-ST elevation acute myocardial infarction and clinical outcomes.

How do older adults self-manage distress and what role does the internet have? A qualitative study (2019)
Thesis
Moult, A. (2019). How do older adults self-manage distress and what role does the internet have? A qualitative study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414985

Although anxiety and depression are common in older adults, the medical terms may not be acceptable to them. Older people are more likely to perceive themselves as experiencing distress, and may also feel responsible for managing their own mood probl... Read More about How do older adults self-manage distress and what role does the internet have? A qualitative study.

Understanding the extent of, and reasons for, diagnostic delay in inflammatory bowel disease (2019)
Thesis
Cross, E. L. (2019). Understanding the extent of, and reasons for, diagnostic delay in inflammatory bowel disease. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417796

Background: Inflammatory Bowel Disease (IBD) is a complex chronic condition affecting the gastrointestinal (GI) system and is sub-classified into Crohn’s Disease (CD) and Ulcerative Colitis (UC). Patients with IBD can present with a multitude of symp... Read More about Understanding the extent of, and reasons for, diagnostic delay in inflammatory bowel disease.

Identifying and managing perinatal anxiety: perspectives of healthcare practitioners. A qualitative study (2019)
Thesis
Silverwood, V. A. (2019). Identifying and managing perinatal anxiety: perspectives of healthcare practitioners. A qualitative study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417798

Background Perinatal mental health (PMH) problems are those which occur during pregnancy or up to 12 months postpartum, and affect up to 20% of women. Perinatal anxiety (PNA) is at least as common as depression and can adversely impact on both mothe... Read More about Identifying and managing perinatal anxiety: perspectives of healthcare practitioners. A qualitative study.

Environmental ultraviolet-B exposures and measured health outcomes in English children (2019)
Thesis
Walker, J. (2019). Environmental ultraviolet-B exposures and measured health outcomes in English children. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417800

Purpose Vitamin D status has been shown to significantly impact extra-skeletal health outcomes. In the UK, the ability of the population to synthesize vitamin D is highly sensitive to environmental factors including ultraviolet-B wavelength light. T... Read More about Environmental ultraviolet-B exposures and measured health outcomes in English children.

Osteoarthritis and premature mortality: pathways for hand, hip, knee and foot osteoarthritis (2019)
Thesis
Seale, B. (2019). Osteoarthritis and premature mortality: pathways for hand, hip, knee and foot osteoarthritis. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417802

Purpose: Evidence of an association between osteoarthritis (OA) and mortality is conflicting; differences in definitions and anatomical sites explain some of the discordance. The high frequency and increasing prevalence of OA highlights the need to... Read More about Osteoarthritis and premature mortality: pathways for hand, hip, knee and foot osteoarthritis.

Supporting people with an intellectual disability and dementia: a constructivist grounded theory study exploring care providers’ views and experiences (2019)
Thesis
Herron, D. L. (2019). Supporting people with an intellectual disability and dementia: a constructivist grounded theory study exploring care providers’ views and experiences. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417814

Background A growing field of research illustrates that carers often lack the necessary training and knowledge to provide the best care and support for people with an intellectual disability and dementia. Less research has explored carers’ support n... Read More about Supporting people with an intellectual disability and dementia: a constructivist grounded theory study exploring care providers’ views and experiences.

Real voices: A participatory action research study to explore the support provided to children visiting adult patients in hospital. (2019)
Thesis
Jervis, J. (2019). Real voices: A participatory action research study to explore the support provided to children visiting adult patients in hospital. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414219

Background: There is evidence that a supportive and open approach to children visiting adult relatives in hospitals has positive benefits for the children, patient, families and healthcare staff. Despite this, many children (

Opioids for musculoskeletal pain and their associations with reproductive and sexual function in women: an epidemiological study (2019)
Thesis
Richardson, E. (2019). Opioids for musculoskeletal pain and their associations with reproductive and sexual function in women: an epidemiological study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/414417

Background One fifth of primary care attendees report chronic non cancer pain (CNCP) most of which is related to musculoskeletal conditions, 12% of these are prescribed strong opioid analgesics. Evidence suggests long-term opioid use causes hypogona... Read More about Opioids for musculoskeletal pain and their associations with reproductive and sexual function in women: an epidemiological study.

The role of deprivation and quality of care on healthy ageing in older people with musculoskeletal pain: a prospective study (2019)
Thesis
Rhys, G. C. (2019). The role of deprivation and quality of care on healthy ageing in older people with musculoskeletal pain: a prospective study. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/417818

Background: Musculoskeletal pain is common in older adults and is associated with a decrease in the Healthy Ageing Index (HAI) (a validated composite ageing measure). Deprivation measures were not included in the HAI. The literature advocates includi... Read More about The role of deprivation and quality of care on healthy ageing in older people with musculoskeletal pain: a prospective study.

The role of social participation in maintaining mental and physical health in older people with musculoskeletal pain (2019)
Thesis
Baker, S. (2019). The role of social participation in maintaining mental and physical health in older people with musculoskeletal pain. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/413137

Background Identifying factors that distinguish between older people with chronic musculoskeletal pain who maintain good mental and physical health, and those who do not, would inform practical programmes for promoting future physical and mental hea... Read More about The role of social participation in maintaining mental and physical health in older people with musculoskeletal pain.