All Outputs (12)

Conceptualising and measuring adherence to exercise for musculoskeletal pain: The Adherence To Exercise for Musculoskeletal Pain Tool (ATEMPT) (2022)
Thesis
Bailey, D. L. (2022). Conceptualising and measuring adherence to exercise for musculoskeletal pain: The Adherence To Exercise for Musculoskeletal Pain Tool (ATEMPT). (Thesis). Keele University

Aim: To develop and test a measurement tool for adherence to exercise for musculoskeletal (MSK) pain. Purpose: A valid and reliable measure of adherence to exercise will improve the interpretation of whether outcomes observed in studies of exercis... Read More about Conceptualising and measuring adherence to exercise for musculoskeletal pain: The Adherence To Exercise for Musculoskeletal Pain Tool (ATEMPT).

Assessing the impact of comorbidity measures on outcomes following acute coronary syndrome (2022)
Thesis
Zhang, F. (2022). Assessing the impact of comorbidity measures on outcomes following acute coronary syndrome. (Thesis). Keele University

Acute coronary syndromes (ACS) are a common acute presentation of cardiovascular disease (CVD) associated with significant morbidity, mortality and societal economic burden. With improvements in medical care and post- ACS survival rates, ACS patients... Read More about Assessing the impact of comorbidity measures on outcomes following acute coronary syndrome.

An interpretive phenomenological study of nursing insights into the formation of the therapeutic nurse patient relationship within acute psychiatric wards (2022)
Thesis
Fieldhouse, C. J. (2022). An interpretive phenomenological study of nursing insights into the formation of the therapeutic nurse patient relationship within acute psychiatric wards. (Thesis). Keele University

This study has concerned itself with the therapeutic nature of the relationship between psychiatric nurses and the inpatients of acute psychiatric wards. In particular it sought the insights that those nurses held in relation to their strategic endea... Read More about An interpretive phenomenological study of nursing insights into the formation of the therapeutic nurse patient relationship within acute psychiatric wards.

Developing tools for inter-site transport of brain tissue models in tissue engineering research (2022)
Thesis
Kabiri, B. (2022). Developing tools for inter-site transport of brain tissue models in tissue engineering research. (Thesis). Keele University

Penetrating traumatic brain injury (pTBI) remains one of the leading causes of death in the younger population in the UK, as no clinical regenerative therapies are available. Experimental therapies currently being screened for efficacy are wide rangi... Read More about Developing tools for inter-site transport of brain tissue models in tissue engineering research.

Systematic reviews of the management of premenstrual disorder through the elimination of ovulation (2022)
Thesis
Naheed, B. (2022). Systematic reviews of the management of premenstrual disorder through the elimination of ovulation. (Thesis). Keele University

Premenstrual syndrome (PMS) is a distressing psychological and somatic disorder of unidentified aetiology occurring during the luteal phase of the menstrual cycle. This thesis includes systematic reviews of the published literature on the therapeutic... Read More about Systematic reviews of the management of premenstrual disorder through the elimination of ovulation.

A metabolomic analysis of cardiac metabolism in a human model of early myocardial ischaemia (2022)
Thesis
Chacko, S. M. (2022). A metabolomic analysis of cardiac metabolism in a human model of early myocardial ischaemia. (Thesis). Keele University

Introduction: Acute myocardial ischaemia and the transition from reversible to irreversible myocardial injury are associated with abnormal metabolic patterns. Advances in metabolomics have extended our capabilities to define these metabolic perturbat... Read More about A metabolomic analysis of cardiac metabolism in a human model of early myocardial ischaemia.

Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis (2022)
Thesis
Burgess, R. M. (2022). Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis. (Thesis). Keele University

Introduction: High quality data on service performance is essential in healthcare. There is however a paucity of publicly reported data in community/primary care musculoskeletal (MSK) services. There is also a lack of guidance on which metrics servic... Read More about Benchmarking community and primary care musculoskeletal services: Developing recommendations using evidence syntheses, consensus methods and secondary data analysis.

Practice Readiness: An English exploratory study describing newly qualified graduate nurses’ perceptions of practice readiness and professional identity (2022)
Thesis
Sargeant, K. E. (2022). Practice Readiness: An English exploratory study describing newly qualified graduate nurses’ perceptions of practice readiness and professional identity. (Thesis). Keele University

Background: Greater understanding of NQNs’ perceptions of their pre-registration and transition experiences, and influences on their perceptions can inform pre-registration curricula and preceptorship programmes to support a positive transition to qu... Read More about Practice Readiness: An English exploratory study describing newly qualified graduate nurses’ perceptions of practice readiness and professional identity.

Investigating the relationship between diabetes and frozen shoulder: longitudinal analysis of primary care medical records (2022)
Thesis
Dyer, B. P. (2022). Investigating the relationship between diabetes and frozen shoulder: longitudinal analysis of primary care medical records. (Thesis). Keele University

Introduction Frozen shoulder, a condition that can cause prolonged pain and disability, has previously been found to be common amongst people with diabetes. This thesis aimed to improve the understanding of the nature of the relationship between dia... Read More about Investigating the relationship between diabetes and frozen shoulder: longitudinal analysis of primary care medical records.

Development and psychometric evaluation of a patient reported outcome measure for polymyalgia rheumatica (2022)
Thesis
Twohig, H. J. (2022). Development and psychometric evaluation of a patient reported outcome measure for polymyalgia rheumatica. (Thesis). Keele University

Background Polymyalgia rheumatica (PMR) causes pain, stiffness and disability in older adults. Measuring the impact of the condition from the patient’s perspective is vital to highquality research and patient-centred care, yet there are no validated... Read More about Development and psychometric evaluation of a patient reported outcome measure for polymyalgia rheumatica.

A transcriptomic-based drug repositioning approach for the identification of novel muscle-specific therapies for spinal muscular atrophy (2022)
Thesis
Hoolachan, J. M. (2022). A transcriptomic-based drug repositioning approach for the identification of novel muscle-specific therapies for spinal muscular atrophy. (Thesis). Keele University

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder (NMD) caused by depleted survival of motor neuron (SMN) levels and characterised by neuronal degeneration and progressive muscle atrophy. Although three approved SMN-depen... Read More about A transcriptomic-based drug repositioning approach for the identification of novel muscle-specific therapies for spinal muscular atrophy.

Cell models to evaluate oligodendrocyte lineage cell growth on biomaterials (2022)
Thesis
Chowdhury, F. (2022). Cell models to evaluate oligodendrocyte lineage cell growth on biomaterials. (Thesis). Keele University

Oligodendrocyte lineage and neuronal cells are essential neural populations required for axonal remyelination after spinal cord injury (SCI). Injection of an exogenous cell population into the site of neural injury has posed translational barriers, s... Read More about Cell models to evaluate oligodendrocyte lineage cell growth on biomaterials.