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Bayesian meta-analytical methods to incorporate multiple surrogate endpoints in drug development process. (2016)
Journal Article
(2016). Bayesian meta-analytical methods to incorporate multiple surrogate endpoints in drug development process. Statistics in Medicine, 1063 - 1089. https://doi.org/10.1002/sim.6776

A number of meta-analytical methods have been proposed that aim to evaluate surrogate endpoints. Bivariate meta-analytical methods can be used to predict the treatment effect for the final outcome from the treatment effect estimate measured on the su... Read More about Bayesian meta-analytical methods to incorporate multiple surrogate endpoints in drug development process..

What Musculoskeletal (MSK) Conditions are Referred from Routine General Practice (GP) and what Impact does this have on Developing Innovative Care Models for Patients with MSK Conditions in Primary Care? (2016)
Journal Article
Heron. (2016). What Musculoskeletal (MSK) Conditions are Referred from Routine General Practice (GP) and what Impact does this have on Developing Innovative Care Models for Patients with MSK Conditions in Primary Care?. https://doi.org/10.4172/2329-9096.1000375

Introduction: The current ethos within the United Kingdom (UK) health system is to encourage community management of health problems, increasing primary care workload. Yet General Practice (GP) is currently in ‘crisis’ with significant workload press... Read More about What Musculoskeletal (MSK) Conditions are Referred from Routine General Practice (GP) and what Impact does this have on Developing Innovative Care Models for Patients with MSK Conditions in Primary Care?.

The Current State of Peritoneal Dialysis (2016)
Journal Article
Mehrotra, R., Devuyst, O., Davies, S. J., & Johnson, D. W. (2016). The Current State of Peritoneal Dialysis. Journal of the American Society of Nephrology, 27(11), 3238 -3252. https://doi.org/10.1681/ASN.2016010112

Technical innovations in peritoneal dialysis (PD), now used widely for the long-term treatment of ESRD, have significantly reduced therapy-related complications, allowing patients to be maintained on PD for longer periods. Indeed, the survival rate f... Read More about The Current State of Peritoneal Dialysis.

The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome (2016)
Journal Article
Chesterton, L. S., Dziedzic, K. S., Van Der Windt, D. A., Davenport, G., Myers, H. L., Rathod, T., …Hay, E. M. (2016). The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome. BMC Musculoskeletal Disorders, 415 - ?. https://doi.org/10.1186/s12891-016-1264-8

BACKGROUND: Patients diagnosed with idiopathic mild to moderate carpal tunnel syndrome (CTS) are usually managed in primary care and commonly treated with night splints and/or corticosteroid injection. The comparative effectiveness of these intervent... Read More about The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome.

PMS74 - Development of the Musculoskeletal Health Questionnaire (MSK-HQ) for Use in Different Conditions and Different Healthcare Pathways (2016)
Journal Article
Hill, J., Kang, S., Benedetto, E., Myers, H., Blackburn, S., Smith, S., …Price, A. (2016). PMS74 - Development of the Musculoskeletal Health Questionnaire (MSK-HQ) for Use in Different Conditions and Different Healthcare Pathways. Value in Health, 19(7), 544 - 544. https://doi.org/10.1016/j.jval.2016.09.1142

Objectives
Musculoskeletal pain is the single greatest cause of years lived with disability. This can include osteoarthritis, inflammatory disorders and musculoskeletal disorders such as back, neck, shoulder, hip, and knee pain. The Arthritis UK Mus... Read More about PMS74 - Development of the Musculoskeletal Health Questionnaire (MSK-HQ) for Use in Different Conditions and Different Healthcare Pathways.

Implementation Science and Employer Disability Practices: Embedding Implementation Factors in Research Designs (2016)
Journal Article
Main, C. (2016). Implementation Science and Employer Disability Practices: Embedding Implementation Factors in Research Designs. Journal of Occupational Rehabilitation, 448 - 464. https://doi.org/10.1007/s10926-016-9677-7

Purpose For work disability research to have an impact on employer policies and practices it is important for such research to acknowledge and incorporate relevant aspects of the workplace. The goal of this article is to summarize recent theoretical... Read More about Implementation Science and Employer Disability Practices: Embedding Implementation Factors in Research Designs.

Effects of Antiretroviral Therapy on the Survival of Human Immunodeficiency Virus-positive Adult Patients in Andhra Pradesh, India: A Retrospective Cohort Study, 2007-2013 (2016)
Journal Article
Bajpai. (2016). Effects of Antiretroviral Therapy on the Survival of Human Immunodeficiency Virus-positive Adult Patients in Andhra Pradesh, India: A Retrospective Cohort Study, 2007-2013. Journal of Preventive Medicine and Public Health, 394 - 405. https://doi.org/10.3961/jpmph.16.073

Objectives
The survival outcomes of antiretroviral treatment (ART) programs have not been systematically evaluated at the state level in India. This retrospective study assessed the survival rates and factors associated with survival among adult hum... Read More about Effects of Antiretroviral Therapy on the Survival of Human Immunodeficiency Virus-positive Adult Patients in Andhra Pradesh, India: A Retrospective Cohort Study, 2007-2013.

CONSORT 2010 statement: extension to randomised pilot and feasibility trials. (2016)
Journal Article
(2016). CONSORT 2010 statement: extension to randomised pilot and feasibility trials. BMJ, 64 - ?. https://doi.org/10.1136/bmj.i5239

The Consolidated Standards of Reporting Trials (CONSORT) statement is a guideline designed to improve the transparency and quality of the reporting of randomised controlled trials (RCTs). In this article we present an extension to that statement for... Read More about CONSORT 2010 statement: extension to randomised pilot and feasibility trials..

Are foot and ankle characteristics associated with falls in people with rheumatoid arthritis? A prospective study. (2016)
Journal Article
(2016). Are foot and ankle characteristics associated with falls in people with rheumatoid arthritis? A prospective study. Arthritis Care and Research, 1150-1155. https://doi.org/10.1002/acr.23131

OBJECTIVE: To determine whether foot and ankle characteristics are associated with falls in people with rheumatoid arthritis (RA). METHODS: Two hundred and one adults with RA were recruited from rheumatology outpatient clinics in Auckland, New Zealan... Read More about Are foot and ankle characteristics associated with falls in people with rheumatoid arthritis? A prospective study..

The junior doctor contract in the National Health Service. (2016)
Journal Article
Mughal, Z., & Mughal, F. (2016). The junior doctor contract in the National Health Service. Journal of Family Medicine and Primary Care, 225 - 227. https://doi.org/10.4103/2249-4863.192329

The progression of the junior doctor contract negotiations within the National Health Service (NHS) has been widely reported. We aim to provide a comprehensive summary of the current state of affairs with the contract negotiations and hope to inform... Read More about The junior doctor contract in the National Health Service..

The persistence of the effects of acupuncture after a course of treatment: A meta-analysis of patients with chronic pain (2016)
Journal Article
(2016). The persistence of the effects of acupuncture after a course of treatment: A meta-analysis of patients with chronic pain. PAIN, 784-793. https://doi.org/10.1097/j.pain.0000000000000747

There is uncertainty regarding how long the effects of acupuncture treatment persist after a course of treatment. We aimed to determine the trajectory of pain scores over time following acupuncture, using a large individual patient dataset from high... Read More about The persistence of the effects of acupuncture after a course of treatment: A meta-analysis of patients with chronic pain.

The persistence of the effects of acupuncture after a course of treatment: A meta-analysis of patients with chronic pain. (2016)
Journal Article
(2016). The persistence of the effects of acupuncture after a course of treatment: A meta-analysis of patients with chronic pain. PAIN, 784-793. https://doi.org/10.1097/j.pain.0000000000000747

There is uncertainty regarding how long the effects of acupuncture treatment persist after a course of treatment. We aimed to determine the trajectory of pain scores over time following acupuncture, using a large individual patient dataset from high... Read More about The persistence of the effects of acupuncture after a course of treatment: A meta-analysis of patients with chronic pain..

Meta-analysis using individual participant data: one-stage and two-stage approaches, and why they may differ. (2016)
Journal Article
(2016). Meta-analysis using individual participant data: one-stage and two-stage approaches, and why they may differ. Statistics in Medicine, 855-875. https://doi.org/10.1002/sim.7141

Meta-analysis using individual participant data (IPD) obtains and synthesises the raw, participant-level data from a set of relevant studies. The IPD approach is becoming an increasingly popular tool as an alternative to traditional aggregate data me... Read More about Meta-analysis using individual participant data: one-stage and two-stage approaches, and why they may differ..

Defining the Na(+)/H(+) exchanger NHE1 interactome in triple-negative breast cancer cells. (2016)
Journal Article
(2016). Defining the Na(+)/H(+) exchanger NHE1 interactome in triple-negative breast cancer cells. Cellular Signalling, 69 - 77. https://doi.org/10.1016/j.cellsig.2016.10.005

Mounting evidence supports a major role for the Na(+)/H(+) exchanger NHE1 in cancer progression and metastasis. NHE1 is hyperactive at the onset of oncogenic transformation, resulting in intracellular alkalinization and extracellular microenvironment... Read More about Defining the Na(+)/H(+) exchanger NHE1 interactome in triple-negative breast cancer cells..

What to do after cardiac rehabilitation programs: the role of the general practitioner in cardiovascular prevention (2016)
Journal Article
Heron. (2016). What to do after cardiac rehabilitation programs: the role of the general practitioner in cardiovascular prevention. Monaldi Archives for Chest Disease, https://doi.org/10.4081/monaldi.2016.755

This paper will review the current role of general practitioners (GPs) in providing cardiovascular prevention for patients after attendance at a cardiac rehabilitation program. Long-term implementation of preventive strategies is needed for continued... Read More about What to do after cardiac rehabilitation programs: the role of the general practitioner in cardiovascular prevention.

Applying causal mediation methods to clinical trial data: What can we learn about why our interventions (don't) work? (2016)
Journal Article
Van Der Windt. (2016). Applying causal mediation methods to clinical trial data: What can we learn about why our interventions (don't) work?. European Journal of Pain, 614-622. https://doi.org/10.1002/ejp.964

BACKGROUND: Many randomized controlled trials (RCTs) of psychosocial interventions for low back pain (LBP) have been found to have only small effects on disability outcomes. Investigations of the specific mechanisms that may lead to an improvement in... Read More about Applying causal mediation methods to clinical trial data: What can we learn about why our interventions (don't) work?.

Does a modified STarT Back Tool predict outcome with a broader group of musculoskeletal patients than back pain? A secondary analysis of cohort data. (2016)
Journal Article
Hill, J., Afolabi, E. K., Lewis, M., Dunn, K., Roddy, E., Van Der Windt, D., & Foster, N. E. (2016). Does a modified STarT Back Tool predict outcome with a broader group of musculoskeletal patients than back pain? A secondary analysis of cohort data. BMJ Open, e012445 - ?. https://doi.org/10.1136/bmjopen-2016-012445

OBJECTIVES: The STarT Back Tool has good predictive performance for non-specific low back pain in primary care. We therefore aimed to investigate whether a modified STarT Back Tool predicted outcome with a broader group of musculoskeletal patients, a... Read More about Does a modified STarT Back Tool predict outcome with a broader group of musculoskeletal patients than back pain? A secondary analysis of cohort data..