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Centre of Mass Acceleration-Derived Variables Detects Differences between Runners of Different Abilities and Fatigue-Related Changes during a Long Distance Over ground Run (2018)
Journal Article
Winter. (2018). Centre of Mass Acceleration-Derived Variables Detects Differences between Runners of Different Abilities and Fatigue-Related Changes during a Long Distance Over ground Run. https://doi.org/10.19080/jpfmts.2018.04.555632

Background: Wireless accelerometers provide a method of performing running assessments in sports-specific environments. The purpose of this study was to investigate differences in running movement using centre of mass acceleration-derived variables b... Read More about Centre of Mass Acceleration-Derived Variables Detects Differences between Runners of Different Abilities and Fatigue-Related Changes during a Long Distance Over ground Run.

Exploring the roles of urinary HAI-1, EpCAM and EGFR in bladder cancer prognosis and risk stratification (2018)
Journal Article
(2018). Exploring the roles of urinary HAI-1, EpCAM and EGFR in bladder cancer prognosis and risk stratification. Oncotarget, https://doi.org/10.18632/oncotarget.25397

Objectives: To investigate whether elevated urinary HAI-1, EpCAM and EGFR are independent prognostic biomarkers within non-muscle-invasive bladder cancer (NMIBC) patients, and have utility for risk stratification to facilitate treatment decisions.... Read More about Exploring the roles of urinary HAI-1, EpCAM and EGFR in bladder cancer prognosis and risk stratification.

Simulation-based power calculations for planning a two-stage individual participant data meta-analysis (2018)
Journal Article
(2018). Simulation-based power calculations for planning a two-stage individual participant data meta-analysis. BMC medical research methodology, 41 -?. https://doi.org/10.1186/s12874-018-0492-z

BACKGROUND Researchers and funders should consider the statistical power of planned Individual Participant Data (IPD) meta-analysis projects, as they are often time-consuming and costly. We propose simulation-based power calculations utilising a two... Read More about Simulation-based power calculations for planning a two-stage individual participant data meta-analysis.

Photodynamic therapy corrects abnormal cancer-associated gene expression observed in actinic keratosis lesions and induces a remodeling effect in photodamaged skin (2018)
Journal Article
Joly, F., Deret, S., Gamboa, B., Menigot, C., Fogel, P., Mounier, C., …Voegel, J. J. (2018). Photodynamic therapy corrects abnormal cancer-associated gene expression observed in actinic keratosis lesions and induces a remodeling effect in photodamaged skin. Journal of Dermatological Science, 91(2), 206-218. https://doi.org/10.1016/j.jdermsci.2018.05.002

Background Actinic keratoses (AK) are proliferations of neoplastic keratinocytes in the epidermis resulting from cumulative exposure to ultraviolet radiation (UVR), which are liable to transform into squamous cell carcinoma (SCC). Organ Transplant R... Read More about Photodynamic therapy corrects abnormal cancer-associated gene expression observed in actinic keratosis lesions and induces a remodeling effect in photodamaged skin.

Incidence, determinants and outcomes of left and right radial access use in patients undergoing percutaneous coronary intervention in the United Kingdom, a national perspective using the British Cardiovascular Intervention Society (BCIS) dataset (2018)
Journal Article
de Belder, M., Nolan, J., Mamas, M., Kinnaird, T., Ludman, P., Potts, J., …Rashid, M. (2018). Incidence, determinants and outcomes of left and right radial access use in patients undergoing percutaneous coronary intervention in the United Kingdom, a national perspective using the British Cardiovascular Intervention Society (BCIS) dataset. JACC. Cardiovascular interventions, 11(11), 1021-1033. https://doi.org/10.1016/j.jcin.2018.01.252

Objectives The authors sought to determine the relationships between left radial access (LRA) or right radial access (RRA) and clinical outcomes using the British Cardiovascular Intervention Society (BCIS) database. Background LRA has been shown... Read More about Incidence, determinants and outcomes of left and right radial access use in patients undergoing percutaneous coronary intervention in the United Kingdom, a national perspective using the British Cardiovascular Intervention Society (BCIS) dataset.

Long-term clinical and cost-effectiveness of collaborative care (vs. usual care): a cluster-randomised trial (2018)
Journal Article
Chew-Graham. (2018). Long-term clinical and cost-effectiveness of collaborative care (vs. usual care): a cluster-randomised trial. https://doi.org/10.1192/bjp.2018.70

Background Collaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown. Aims To explore the long-term (24-month) effectiveness and cost-effectiveness of collaborati... Read More about Long-term clinical and cost-effectiveness of collaborative care (vs. usual care): a cluster-randomised trial.

Psychosocial variables and presence, severity and prognosis of plantar heel pain: a systematic review of cross-sectional and prognostic associations (2018)
Journal Article
(2018). Psychosocial variables and presence, severity and prognosis of plantar heel pain: a systematic review of cross-sectional and prognostic associations. Musculoskeletal Care, 329-338. https://doi.org/10.1002/msc.1246

Objective: Plantar heel pain (PHP) is often disabling, and persistent symptoms are common. Psychosocial variables are known to affect pain and disability but the association of these factors with PHP has yet to be established. The purpose of the pres... Read More about Psychosocial variables and presence, severity and prognosis of plantar heel pain: a systematic review of cross-sectional and prognostic associations.

Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy (2018)
Journal Article
Paskins, Mallen, Bucknall, Hider, Muller, Helliwell, & Roddy. (2018). Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy. Canadian Medical Association Journal, E581 -E587. https://doi.org/10.1503/cmaj.170806

BACKGROUND: Previous studies that quantified the risk of fracture among patients with gout and assessed the potential effect of urate-lowering therapy have provided conflicting results. Our study aims to provide better estimates of risk by minimizing... Read More about Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy.

‘Treading water but drowning slowly’: what are GPs’ experiences of living and working with mental illness and distress in England? A qualitative study (2018)
Journal Article
Chew-Graham. (2018). ‘Treading water but drowning slowly’: what are GPs’ experiences of living and working with mental illness and distress in England? A qualitative study. BMJ Open, https://doi.org/10.1136/bmjopen-2017-018620

Objectives This paper provides an in-depth account of general practitioners’ (GPs) experiences of living and working with mental illness and distress, as part of a wider study reporting the barriers and facilitators to help-seeking for mental illnes... Read More about ‘Treading water but drowning slowly’: what are GPs’ experiences of living and working with mental illness and distress in England? A qualitative study.

EULAR recommendations for the health professional’s approach to pain management in inflammatory arthritis and osteoarthritis (2018)
Journal Article
Paskins. (2018). EULAR recommendations for the health professional’s approach to pain management in inflammatory arthritis and osteoarthritis. Annals of the Rheumatic Diseases, 797-807. https://doi.org/10.1136/annrheumdis-2017-212662

Pain is the predominant symptom for people with inflammatory arthritis (IA) and osteoarthritis (OA) mandating the development of evidence-based recommendations for the health professional’s approach to pain management. A multidisciplinary task force... Read More about EULAR recommendations for the health professional’s approach to pain management in inflammatory arthritis and osteoarthritis.

Involving the public in health research in Latin America: making the case for mental health (2018)
Journal Article
Troya, M. . I., Bartlam, B., & Chew-Graham, C. A. (2018). Involving the public in health research in Latin America: making the case for mental health. Pan American Journal of Public Health / Revista Panamericana de Salud Pública, 1-6. https://doi.org/10.26633/rpsp.2018.45

Patient and Public Involvement and Engagement (PPIE) has been increasingly encouraged in health services and research over the last two decades. Particularly strong evidence has been presented with regard to the impact PPIE has in certain research ar... Read More about Involving the public in health research in Latin America: making the case for mental health.

Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system. (2018)
Journal Article
Kwong. (2018). Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system. Journal of Ovarian Research, 36 - ?. https://doi.org/10.1186/s13048-018-0403-2

BACKGROUND: Ovarian cancer stem cells (OCSCs) contribute to the poor prognosis of ovarian cancer. Involvement of the androgen receptor (AR) in the malignant behaviors of other tumors has been reported. However, whether AR associates with Nanog (a ste... Read More about Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system..

Characteristics of Patients Initializing Peritoneal Dialysis Treatment From 2007 to 2014: Analysis From Henan Peritoneal Dialysis Registry data (2018)
Journal Article
Yu. (2018). Characteristics of Patients Initializing Peritoneal Dialysis Treatment From 2007 to 2014: Analysis From Henan Peritoneal Dialysis Registry data

Introduction. This study aimed to assess the number and profiles of patients initializing peritoneal dialysis form the Henan Peritoneal Dialysis Registry, a provincial database in central China. Materials and Methods. All patients aged 18 years... Read More about Characteristics of Patients Initializing Peritoneal Dialysis Treatment From 2007 to 2014: Analysis From Henan Peritoneal Dialysis Registry data.

Comparison of Drug Discontinuation, Effectiveness, and Safety Between Clinical Trial Eligible and Ineligible Patients in BADBIR. (2018)
Journal Article
Mason. (2018). Comparison of Drug Discontinuation, Effectiveness, and Safety Between Clinical Trial Eligible and Ineligible Patients in BADBIR. JAMA Dermatology, 154(5), 581 - 588. https://doi.org/10.1001/jamadermatol.2018.0183

Importance: Patients with psoriasis enrolled in clinical trials of biologics may not be representative of the real-world population. There is evidence that patients ineligible for such trials have a greater risk of serious adverse events (SAEs), but... Read More about Comparison of Drug Discontinuation, Effectiveness, and Safety Between Clinical Trial Eligible and Ineligible Patients in BADBIR..

Management of gout by UK rheumatologists: a British Society for Rheumatology national audit (2018)
Journal Article
Roddy. (2018). Management of gout by UK rheumatologists: a British Society for Rheumatology national audit. Rheumatology, 826-830. https://doi.org/10.1093/rheumatology/kex521

Objectives To assess the concordance of gout management by UK rheumatologists with evidence-based best-practice recommendations. Methods Data were collected on patients newly referred to UK rheumatology out-patient departments over an 8-week per... Read More about Management of gout by UK rheumatologists: a British Society for Rheumatology national audit.

Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis (2018)
Journal Article
(2018). Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. Journal of Pain, 455-474. https://doi.org/10.1016/j.jpain.2017.11.005

Abstract Despite wide use in clinical practice, acupuncture remains a controversial treatment for chronic pain. Our objective was to update an individual patient data meta-analysis to determine the effect size of acupuncture for four chronic pain con... Read More about Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis.

239 Prevalence of impaired health literacy in patients with rheumatoid arthritis and its association with medication understanding and patient outcomes (2018)
Presentation / Conference
Grose-Hodge, E., Scott, I., Dale, N., Ryan, S., Machin, A., & Hider, S. (2018, May). 239 Prevalence of impaired health literacy in patients with rheumatoid arthritis and its association with medication understanding and patient outcomes. Poster presented at British Society for Rheumatology Annual Conference 2018, The ACC & Exhibition Centre Liverpool, Liverpool, UK

Background: Managing long-term conditions like rheumatoid arthritis (RA) involves clinicians imparting information effectively in brief appointments, often supplemented with written information. Health literacy (HL), defined as the degree to which in... Read More about 239 Prevalence of impaired health literacy in patients with rheumatoid arthritis and its association with medication understanding and patient outcomes.

FP467 CHANGES IN DIALYSIS PRESCRIPTION AFFECT THE TIME COURSE OF SOLUTE TRANSPORT IN PERITONEAL DIALYSIS (2018)
Journal Article
Brenna, I., Elphick, E., Lambie, M., & Davies, S. (2018). FP467 CHANGES IN DIALYSIS PRESCRIPTION AFFECT THE TIME COURSE OF SOLUTE TRANSPORT IN PERITONEAL DIALYSIS. Nephrology Dialysis Transplantation, 33(suppl_1), i194-i194. https://doi.org/10.1093/ndt/gfy104.fp467

INTRODUCTION AND AIMS: Long term peritoneal dialysis (PD) is associated with increased peritoneal solute transport rate (PSTR), which correlates with hard outcomes. Whether different clinical approaches affect PSTR rate of increase is unclear. MET... Read More about FP467 CHANGES IN DIALYSIS PRESCRIPTION AFFECT THE TIME COURSE OF SOLUTE TRANSPORT IN PERITONEAL DIALYSIS.