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Quantitative fibronectin to help decision-making in women with symptoms of preterm labour (QUIDS) part 1: Individual participant data meta-analysis and health economic analysis. (2018)
Journal Article
(2018). Quantitative fibronectin to help decision-making in women with symptoms of preterm labour (QUIDS) part 1: Individual participant data meta-analysis and health economic analysis. BMJ Open, e020796 - ?. https://doi.org/10.1136/bmjopen-2017-020796

INTRODUCTION: The aim of the QUIDS study is to develop a decision support tool for the management of women with symptoms and signs of preterm labour, based on a validated prognostic model using quantitative fetal fibronectin (qfFN) concentration, in... Read More about Quantitative fibronectin to help decision-making in women with symptoms of preterm labour (QUIDS) part 1: Individual participant data meta-analysis and health economic analysis..

Antithrombotic therapy in patients receiving saphenous vein coronary artery bypass grafts: a protocol for a systematic review and network meta-analysis. (2018)
Journal Article
Mamas. (2018). Antithrombotic therapy in patients receiving saphenous vein coronary artery bypass grafts: a protocol for a systematic review and network meta-analysis. BMJ Open, e019555 - ?. https://doi.org/10.1136/bmjopen-2017-019555

INTRODUCTION: The current evidence for the prevention of saphenous vein graft failure (SVGF) after coronary artery bypass graft (CABG) surgery consists of direct head-to-head comparison of treatments (including placebo) in randomised-controlled trial... Read More about Antithrombotic therapy in patients receiving saphenous vein coronary artery bypass grafts: a protocol for a systematic review and network meta-analysis..

Non-disclosure of symptoms in primary care: an observational study (2018)
Journal Article
Paskins, Z., Sanders, T., Croft, P. R., Green, J., McKinley, R., & Hassell, A. B. (2018). Non-disclosure of symptoms in primary care: an observational study. Family Practice, https://doi.org/10.1093/fampra/cmy023

Background: Symptoms form a major component of patient agendas, with the need for an explanation of symptoms being a prominent reason for consultation. Objectives: To estimate the prevalence of different symptoms pre-consultation, to investigate whet... Read More about Non-disclosure of symptoms in primary care: an observational study.

Primary care challenges in diagnosing and referring patients with suspected rheumatoid arthritis: a national cross-sectional gp survey (2018)
Journal Article
Hider, & Mallen. (2018). Primary care challenges in diagnosing and referring patients with suspected rheumatoid arthritis: a national cross-sectional gp survey. Rheumatology Advances in Practice, https://doi.org/10.1093/rap/rky012

Objectives National guidelines advocate referring patients with persistent synovitis to rheumatology within 3 working days of presentation to primary care. This infrequently occurs. We aimed to identify modifiable barriers to early referral of suspe... Read More about Primary care challenges in diagnosing and referring patients with suspected rheumatoid arthritis: a national cross-sectional gp survey.

Clinical diagnostic model for sciatica developed in primary care patients with low back-related leg pain (2018)
Journal Article
Stynes, S., Konstantinou, K., Ogollah, R., Hay, E., & Dunn, K. (2018). Clinical diagnostic model for sciatica developed in primary care patients with low back-related leg pain. PloS one, 1 -14. https://doi.org/10.1371/journal.pone.0191852

Background Identification of sciatica may assist timely management but can be challenging in clinical practice. Diagnostic models to identify sciatica have mainly been developed in secondary care settings with conflicting reference standard selection... Read More about Clinical diagnostic model for sciatica developed in primary care patients with low back-related leg pain.

UK-South Asian patients' experiences of and satisfaction toward receiving information about biologics in rheumatoid arthritis (2018)
Journal Article
Mallen. (2018). UK-South Asian patients' experiences of and satisfaction toward receiving information about biologics in rheumatoid arthritis. Patient Preference and Adherence, 489 -497. https://doi.org/10.2147/ppa.s153741

Background: Rheumatoid arthritis (RA) causes painful joint inflammation and is incurable, but treatments control RA. Drug regimens are complex, and patients often do not take their medication as expected. Poor medication adherence can lead to poorly... Read More about UK-South Asian patients' experiences of and satisfaction toward receiving information about biologics in rheumatoid arthritis.

Case Studies of Interprofessional Education Initiatives From Five Countries: Case Studies of Five Interprofessional Education Initiatives (2018)
Journal Article
Levett-Jones, T., Burdett, T., Chow, Y. L., Jönsson, L., Lasater, K., Mathews, L. R., …Wihlborg, J. (2018). Case Studies of Interprofessional Education Initiatives From Five Countries: Case Studies of Five Interprofessional Education Initiatives. Journal of Nursing Scholarship, 50(3), 324-332. https://doi.org/10.1111/jnu.12384

Background Although teamwork and interprofessional collaboration are critical to patient safety, nursing, medical, and allied health graduates often feel ill-prepared to confidently communicate and collaborate with other team members. While interpro... Read More about Case Studies of Interprofessional Education Initiatives From Five Countries: Case Studies of Five Interprofessional Education Initiatives.

Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial (2018)
Journal Article
Kigozi, J., Jowett, S., Nicholl, B. I., Lewis, M., Bartlam, B., Green, D., …Mallen, C. D. (2018). Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial. Arthritis Care and Research, 70(12), 1787-1794. https://doi.org/10.1002/acr.23568

OBJECTIVE: To investigate the cost-effectiveness (cost-utility) of introducing general practitioner screening for anxiety and depression in patients consulting with osteoarthritis (OA). METHODS: A cluster-randomised trial-based economic evaluation to... Read More about Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial.

The predictive ability of the STarT Back Tool was limited in people with chronic low back pain: a prospective cohort study (2018)
Journal Article
Hill, J. (2018). The predictive ability of the STarT Back Tool was limited in people with chronic low back pain: a prospective cohort study. Journal of Physiotherapy, 107-113. https://doi.org/10.1016/j.jphys.2018.02.009

Questions In people with chronic non-specific low back pain (LBP), what is the predictive and discriminative validity of the STarT Back Tool (SBT) for pain intensity, self-reported LBP-related disability, and global self-perceived change at 1-year f... Read More about The predictive ability of the STarT Back Tool was limited in people with chronic low back pain: a prospective cohort study.

Bmi1+ Progenitor Cell Dynamics in Murine Cornea During Homeostasis and Wound Healing (2018)
Journal Article
(2018). Bmi1+ Progenitor Cell Dynamics in Murine Cornea During Homeostasis and Wound Healing. STEM CELLS, 562-573. https://doi.org/10.1002/stem.2767

The outermost layer of the eye, the cornea, is renewed continuously throughout life. Stem cells of the corneal epithelium reside in the limbus at the corneal periphery and ensure homeostasis of the central epithelium. However, in young mice, homeosta... Read More about Bmi1+ Progenitor Cell Dynamics in Murine Cornea During Homeostasis and Wound Healing.

Testing a Model of Consultation-based Reassurance and Back Pain Outcomes with Psychological Risk as Moderator: A Prospective Cohort Study (2018)
Journal Article
Hill, J. (2018). Testing a Model of Consultation-based Reassurance and Back Pain Outcomes with Psychological Risk as Moderator: A Prospective Cohort Study. Clinical Journal of Pain, 339-348. https://doi.org/10.1097/AJP.0000000000000541

Objectives:Reassurance is an essential part of treatment for low back pain (LBP), but evidence on effective methods to deliver reassurance remains scarce. The interaction between consultation-based reassurance and patients' psychological risk is unkn... Read More about Testing a Model of Consultation-based Reassurance and Back Pain Outcomes with Psychological Risk as Moderator: A Prospective Cohort Study.

273 Anational survey of the roles and training of healthcare assistants inrheumatology departments (2018)
Journal Article
Robinson, S., Ryan, S., Heslop, P., Hassell, A., & Walker, D. (2018). 273 Anational survey of the roles and training of healthcare assistants inrheumatology departments. Rheumatology, 57(suppl_3), https://doi.org/10.1093/rheumatology/key075.497

Background: Health care assistants (HCAs) perform many roles in rheumatology departments which were previously performed by health care professionals (HCPs). HCPs have a responsibility to ensure HCAs are competent to perform delegated tasks. It is es... Read More about 273 Anational survey of the roles and training of healthcare assistants inrheumatology departments.

i049 The importance of identifying and managing co-morbid anxiety and depression in people with rheumatological conditions (2018)
Journal Article
Chew-Graham, C. (2018). i049 The importance of identifying and managing co-morbid anxiety and depression in people with rheumatological conditions. Rheumatology, 57(suppl_3), https://doi.org/10.1093/rheumatology/key075.049

Anxiety and depression are common mental disorders and major contributors to the overall global burden of disease. Depression is a risk factor for suicide. Where anxiety and depression are co-morbid with a long term physical condition, the morbidity... Read More about i049 The importance of identifying and managing co-morbid anxiety and depression in people with rheumatological conditions.

229 The impact of the EIA clinic on early RA care (2018)
Journal Article
Yates, M., Galloway, J., Snowden, N., Norton, S., Macgregor, A. J., Rivett, A., …Ledingham, J. M. (2018). 229 The impact of the EIA clinic on early RA care. Rheumatology, 57(suppl_3), https://doi.org/10.1093/rheumatology/key075.453

Background: Trials indicate early intervention and tight disease control in rheumatoid arthritis (RA) associate with improved outcomes. This is reflected in the NICE quality statements for early RA care, and in the Best Practice Tariff for RA. Many s... Read More about 229 The impact of the EIA clinic on early RA care.

315 Searching for a prodrome for rheumatoid arthritis in the primary care record: a clinical practice research datalink study (2018)
Journal Article
Muller, S., Hider, S., Machin, A., Stack, R., Hayward, R., Raza, K., & Mallen, C. (2018). 315 Searching for a prodrome for rheumatoid arthritis in the primary care record: a clinical practice research datalink study. Rheumatology, 57(suppl_3), https://doi.org/10.1093/rheumatology/key075.539

Background: Outcomes in rheumatoid arthritis (RA) are improved by early treatment with disease modifying anti-rheumatic drugs (DMARD). This requires prompt recognition of symptoms when patients present to their general practitioner (GP) in order to i... Read More about 315 Searching for a prodrome for rheumatoid arthritis in the primary care record: a clinical practice research datalink study.

A randomised controlled trial, cost-effectiveness and process evaluation of the implementation of self-management for chronic gastrointestinal disorders in primary care, and linked projects on identification and risk assessment (2018)
Journal Article
Thompson, D. G., O’Brien, S., Kennedy, A., Rogers, A., Whorwell, P., Lovell, K., …Beech, P. A randomised controlled trial, cost-effectiveness and process evaluation of the implementation of self-management for chronic gastrointestinal disorders in primary care, and linked projects on identification and risk assessment. Programme Grants for Applied Research, 6(1), 1-154. https://doi.org/10.3310/pgfar06010

Background Chronic gastrointestinal disorders are major burdens in primary care. Although there is some evidence that enhancing self-management can improve outcomes, it is not known if such models of care can be implemented at scale in routine NHS s... Read More about A randomised controlled trial, cost-effectiveness and process evaluation of the implementation of self-management for chronic gastrointestinal disorders in primary care, and linked projects on identification and risk assessment.

Predicting dementia from primary care records: A systematic review and meta-analysis (2018)
Journal Article
Ford, E., Greenslade, N., Paudyal, P., Bremner, S., Smith, H. E., Banerjee, S., …Cassell, J. (2018). Predicting dementia from primary care records: A systematic review and meta-analysis. PloS one, e0194735 - e0194735. https://doi.org/10.1371/journal.pone.0194735

Introduction Possible dementia is usually identified in primary care by general practitioners (GPs) who refer to specialists for diagnosis. Only two-thirds of dementia cases are currently recorded in primary care, so increasing the proportion of case... Read More about Predicting dementia from primary care records: A systematic review and meta-analysis.

The real evidence for polymyalgia rheumatica as a paraneoplastic syndrome. (2018)
Journal Article
Muller, S., Hider, S., Helliwell, T., Partington, R., & Mallen, C. (2018). The real evidence for polymyalgia rheumatica as a paraneoplastic syndrome. Reumatismo, 23 - 34. https://doi.org/10.4081/reumatismo.2018.1031

The aim of this study was to systematically consider the evidence for polymyalgia rheumatica (PMR) as a paraneoplastic disease. A systematic review of Medline and Embase was conducted from their inception to February 2017. Risk of bias was assessed u... Read More about The real evidence for polymyalgia rheumatica as a paraneoplastic syndrome..

Physiotherapists’ views of implementing a stratified treatment approach for patients with low back pain in Germany: a qualitative study (2018)
Journal Article
Karstens, S., Kuithan, P., Joos, S., Hill, J. C., Wensing, M., Steinhäuser, J., …Szecsenyi, J. (2018). Physiotherapists’ views of implementing a stratified treatment approach for patients with low back pain in Germany: a qualitative study. BMC Health Services Research, 18, Article 214. https://doi.org/10.1186/s12913-018-2991-3

Background The STarT-Back-Approach (STarT: Subgroups for Targeted Treatment) was developed in the UK and has demonstrated clinical and cost effectiveness. Based on the results of a brief questionnaire, patients with low back pain are stratified into... Read More about Physiotherapists’ views of implementing a stratified treatment approach for patients with low back pain in Germany: a qualitative study.