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The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka (2018)
Journal Article
(2018). The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka. BMC Public Health, 1-15. https://doi.org/10.1186/s12889-017-4992-2

BACKGROUND: The disease burden related to mental disorders and metabolic syndrome is growing in low-and middle-income countries (LMIC). The Colombo Twin and Singleton Study (COTASS) is a population-based sample of twins and singletons in Colombo, Sri... Read More about The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka.

What are the sources of stress and distress for general practitioners working in England? A qualitative study. (2018)
Journal Article
Chew-Graham. (2018). What are the sources of stress and distress for general practitioners working in England? A qualitative study. BMJ Open, e017361 - ?. https://doi.org/10.1136/bmjopen-2017-017361

OBJECTIVES: This paper reports the sources of stress and distress experienced by general practitioners (GP) as part of a wider study exploring the barriers and facilitators to help-seeking for mental illness and burnout among this medical population.... Read More about What are the sources of stress and distress for general practitioners working in England? A qualitative study..

Clinicopathological and prognostic significance of blood microvessel density in endometrial cancer: a meta-analysis and subgroup analysis (2018)
Journal Article
Wang, J. Z., Xiong, Y. J., Man, G. C. W., Chen, X. Y., Kwong, J., & Wang, C. C. (2018). Clinicopathological and prognostic significance of blood microvessel density in endometrial cancer: a meta-analysis and subgroup analysis. Archives of Gynecology and Obstetrics, 297(3), 731-740. https://doi.org/10.1007/s00404-018-4648-1

Objective The study aimed to systematically review the association between angiogenesis and clinicopathological characteristics and its prognostic value in patients with endometrial cancer. Methods Eligible studies were searched in PubMed, Embas... Read More about Clinicopathological and prognostic significance of blood microvessel density in endometrial cancer: a meta-analysis and subgroup analysis.

Is hypnotherapy an acceptable treatment option for children with habit cough? (2018)
Journal Article
Gilchrist, F. (2018). Is hypnotherapy an acceptable treatment option for children with habit cough?. Complementary Therapies in Medicine, 27 - 28. https://doi.org/10.1016/j.ctim.2018.01.005

Habit cough is a chronic, persistent dry cough which occurs in children only when awake. It is considered functional (non-organic) and can have a significant impact on the quality of life of the child and their family. One possible treatment option f... Read More about Is hypnotherapy an acceptable treatment option for children with habit cough?.

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article
Mallen, Roddy, Bucknall, Hider, Muller, Paskins, & Helliwell. (2018). Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study. BMC Medicine, https://doi.org/10.1186/s12916-017-0987-1

Background Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.

Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up. (2018)
Journal Article
Stynes, S., Konstantinou, K., Ogollah, R., Hay, E. M., & Dunn, K. M. (2018). Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up. PAIN, 159(4), https://doi.org/10.1097/j.pain.0000000000001147

Traditionally, low back-related leg pain (LBLP) is diagnosed clinically as referred leg pain or sciatica (nerve root involvement). However, within the spectrum of LBLP, we hypothesised that there may be other unrecognised patient subgroups. This stud... Read More about Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up..

Plasticity within the niche ensures the maintenance of aSox2+stem cell population in the mouse incisor. (2018)
Journal Article
(2018). Plasticity within the niche ensures the maintenance of aSox2+stem cell population in the mouse incisor. Development, https://doi.org/10.1242/dev.155929

In mice, the incisors grow throughout the animal's life, and this continuous renewal is driven by dental epithelial and mesenchymal stem cells.Sox2is a principal marker of the epithelial stem cells that reside in the mouse incisor stem cell niche, ca... Read More about Plasticity within the niche ensures the maintenance of aSox2+stem cell population in the mouse incisor..

HumanMethylation450K Array–Identified Biomarkers Predict Tumour Recurrence/Progression at Initial Diagnosis of High-risk Non-muscle Invasive Bladder Cancer (2018)
Journal Article
Kitchen, M. O., Bryan, R. T., Emes, R. D., Luscombe, C. J., Cheng, K., Zeegers, M. P., …Fryer, A. A. (2018). HumanMethylation450K Array–Identified Biomarkers Predict Tumour Recurrence/Progression at Initial Diagnosis of High-risk Non-muscle Invasive Bladder Cancer. Biomarkers in Cancer, 10, 1179299X1775192. https://doi.org/10.1177/1179299x17751920

Background: High-risk non-muscle invasive bladder cancer (HR-NMIBC) is a clinically unpredictable disease. Despite clinical risk estimation tools, many patients are undertreated with intra-vesical therapies alone, whereas others may be over-treated... Read More about HumanMethylation450K Array–Identified Biomarkers Predict Tumour Recurrence/Progression at Initial Diagnosis of High-risk Non-muscle Invasive Bladder Cancer.

A survey of general practitioners' attitudes towards psychiatry. (2018)
Journal Article
(2018). A survey of general practitioners' attitudes towards psychiatry. https://doi.org/10.1192/pb.bp.109.027896

Aims and method There is a lack of current data regarding attitudes of doctors towards psychiatry. General practitioners (GPs) are increasingly involved in teaching psychiatry, and their attitudes towards psychiatry may affect their ability to promo... Read More about A survey of general practitioners' attitudes towards psychiatry..

Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. (2018)
Journal Article
Choudry, A., & Farooq, S. (2018). Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views. BJPsych Bulletin, 345 - 352. https://doi.org/10.1192/pb.bp.116.055269

Aims and method To review the literature to examine the factors that may be affecting recruitment into psychiatry in the UK. We systematically searched four databases to identify studies from 1974 to 2016 and identified 27 papers that met the specifi... Read More about Systematic review into factors associated with the recruitment crisis in psychiatry in the UK: students', trainees' and consultants' views..

Facebook in general practice: a service evaluation in one health economy. (2018)
Journal Article
(2018). Facebook in general practice: a service evaluation in one health economy. British Journal of General Practice Open (BJGP Open), bjgpopen17X101181 - ?. https://doi.org/10.3399/bjgpopen17X101181

Background: Social media has been utilised in a variety of healthcare settings. While its potential for extending healthcare services is recognised by the NHS, potential pitfalls exist. The place, benefits and practical problems of using Facebook in... Read More about Facebook in general practice: a service evaluation in one health economy..

Rotator cuff disorders: a survey of current (2016) UK physiotherapy practice. (2018)
Journal Article
(2018). Rotator cuff disorders: a survey of current (2016) UK physiotherapy practice. Shoulder and Elbow, 52 - 61. https://doi.org/10.1177/1758573217717103

Background: Shoulder pain is a common musculoskeletal presentation, with disorders of the rotator cuff (RC) regarded as the most frequent cause. Conservative treatment is often the initial management; however, findings from a previous survey showed c... Read More about Rotator cuff disorders: a survey of current (2016) UK physiotherapy practice..

Risk of cancer in patients with psoriasis on biological therapies: a systematic review (2018)
Journal Article
Peleva, E., Exton, L. S., Kelley, K., Kleyn, C. E., Mason, K. J., & Smith, C. H. (2018). Risk of cancer in patients with psoriasis on biological therapies: a systematic review. British Journal of Dermatology, 178(1), 103-113. https://doi.org/10.1111/bjd.15830

Background Biological therapies are highly effective in psoriasis, but have profound effects on innate and adaptive immune pathways that may negatively impact on cancer immunosurveillance mechanisms. Objectives To investigate the risk of cancer... Read More about Risk of cancer in patients with psoriasis on biological therapies: a systematic review.

Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669). (2018)
Journal Article
Wynne-Jones, G., Artus, M., Bishop, A., Lawton, S., Lewis, M., Jowett, S., …Van Der Windt, D. (2018). Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669). PAIN, 159(1), 128-138. https://doi.org/10.1097/j.pain.0000000000001075

Musculoskeletal pain is a common cause of work absence and early intervention is advocated to prevent the adverse health and economic consequences of longer-term absence. This cluster randomised controlled trial investigated the effect of introducing... Read More about Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669)..

The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. (2018)
Journal Article
Healey, E., Herron, D., Hider, S., Bucknall, M., Cooke, K., Finney, A., …Chew-Graham, C. (2018). The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial. Journal of Comorbidity, 8(1), https://doi.org/10.1177/2235042X18792373

Background: Patients with inflammatory rheumatic conditions such as rheumatoid arthritis, polymyalgia rheumatica and ankylosing spondylitis are at increased risk of common comorbidities such as cardiovascular disease, osteoporosis and anxiety and dep... Read More about The INCLUDE study: INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community; identifying multimorbidity: Protocol for a pilot randomized controlled trial..

An evaluation of the clinical skills and experience within an orthopaedic Integrated Clinical Assessment and Treatment Service (2018)
Journal Article
Feist-Wilson, S., & Heron, N. (2018). An evaluation of the clinical skills and experience within an orthopaedic Integrated Clinical Assessment and Treatment Service. British Journal of General Practice Open (BJGP Open), bjgpopen17X101217 - bjgpopen17X101217. https://doi.org/10.3399/bjgpopen17X101217

Background General practice in the UK is ‘in crisis’. With 20% of GP workload relating to musculoskeletal (MSK) problems, an orthopaedic Integrated Clinical Assessment and Treatment Service (ICATS) could help support assessment of these patients in p... Read More about An evaluation of the clinical skills and experience within an orthopaedic Integrated Clinical Assessment and Treatment Service.

Hemiarthroplasty proximal femoral endoprostheses following tumour reconstruction: is acetabular replacement necessary? (2018)
Journal Article
Stevenson, J. D., Kumar, V. S., Cribb, G. L., & Cool, P. (2018). Hemiarthroplasty proximal femoral endoprostheses following tumour reconstruction: is acetabular replacement necessary?. The Bone & Joint Journal, 100-B(1), 101-108. https://doi.org/10.1302/0301-620x.100b1.bjj-2017-0005.r1

Aims Dislocation rates are reportedly lower in patients requiring proximal femoral hemiarthroplasty than for patients undergoing hip arthroplasty for neoplasia. Without acetabular replacement, pain due to acetabular wear necessitating revision surge... Read More about Hemiarthroplasty proximal femoral endoprostheses following tumour reconstruction: is acetabular replacement necessary?.