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TCT CONNECT-41 Impact of Chronic Kidney Disease on Coronary Revascularization and In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction (2020)
Journal Article
Panchal, H., Zheng, S., White, C., Leinaar, E., Mukherjee, D., Mamas, M., …Paul, T. (2020). TCT CONNECT-41 Impact of Chronic Kidney Disease on Coronary Revascularization and In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction. Journal of the American College of Cardiology, 76(17), B18. https://doi.org/10.1016/j.jacc.2020.09.072

Background Chronic kidney disease (CKD) in patients with ST-segment elevation myocardial infarction (STEMI) has been associated with worse outcomes. Our study sought to assess the impact of CKD on guideline-directed coronary revascularization and ou... Read More about TCT CONNECT-41 Impact of Chronic Kidney Disease on Coronary Revascularization and In-Hospital Outcomes in Patients With Acute ST-Segment Elevation Myocardial Infarction.

TCT CONNECT-247 Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Bi-national Analysis Derived From the United Kingdom and United States (2020)
Journal Article
Nagaraja, V., Rashid, M., Anderson, H., Ludman, P., Kapadia, S., Starling, R., …Mamas, M. (2020). TCT CONNECT-247 Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Bi-national Analysis Derived From the United Kingdom and United States. Journal of the American College of Cardiology, 76(17), B109. https://doi.org/10.1016/j.jacc.2020.09.264

Background Five years after transplantation, coronary allograft vasculopathy and late graft failure account for 32% of all mortality. The current role of percutaneous coronary intervention (PCI) in coronary allograft vasculopathy is unclear and cons... Read More about TCT CONNECT-247 Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Bi-national Analysis Derived From the United Kingdom and United States.

TCT CONNECT-266 Cobalt Chromium Biolimus Drug-Eluting Stents Compared With Stainless Steel Biolimus Drug-Eluting Stents: Final Results of BMX Alpha (2020)
Journal Article
Alexander Menown, I. B., Mamas, M., Cotton, J., Hildick-Smith, D., Eberli, F., Leibundgut, G., …Oldroyd, K. (2020). TCT CONNECT-266 Cobalt Chromium Biolimus Drug-Eluting Stents Compared With Stainless Steel Biolimus Drug-Eluting Stents: Final Results of BMX Alpha. Journal of the American College of Cardiology, 76(17), B116. https://doi.org/10.1016/j.jacc.2020.09.283

Background Thinner stent struts may improve deliverability and conformability and reduce vessel injury. The final clinical outcomes of the thinner strut (84 to 88 μm) cobalt chromium biolimus eluting stent from the BioMatrix (BMX) Alpha registry are... Read More about TCT CONNECT-266 Cobalt Chromium Biolimus Drug-Eluting Stents Compared With Stainless Steel Biolimus Drug-Eluting Stents: Final Results of BMX Alpha.

The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort. (2020)
Journal Article
(2020). The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort. Journal of Clinical Medicine, https://doi.org/10.3390/jcm9103374

OBJECTIVE: The purpose of this study was to evaluate the added value of radiographs for diagnosing knee osteoarthritis (KOA) by general practitioners (GPs) and secondary care physicians (SPs). METHODS: Seventeen GPs and nineteen SPs were recruited to... Read More about The Added Value of Radiographs in Diagnosing Knee Osteoarthritis Is Similar for General Practitioners and Secondary Care Physicians; Data from the CHECK Early Osteoarthritis Cohort..

Factors associated with disability in patients with rheumatoid arthritis with persistent moderate disease activity: a retrospective cohort study (2020)
Journal Article
Scott, I. C., Mount, J., Barry, J., & Kirkham, B. (2020). Factors associated with disability in patients with rheumatoid arthritis with persistent moderate disease activity: a retrospective cohort study. BMC Rheumatology, 63 - ?. https://doi.org/10.1186/s41927-020-00161-4

Background: Many patients with rheumatoid arthritis (RA) do not attain remission/low disease activity, remaining in a moderate disease activity state (MDAS) with ongoing disability and impaired quality of life (QoL). If patients in persistent MDAS wi... Read More about Factors associated with disability in patients with rheumatoid arthritis with persistent moderate disease activity: a retrospective cohort study.

Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality (2020)
Journal Article
Mohamed, M. O., Banerjee, A., Clarke, S., de Belder, M., Patwala, A., Goodwin, A. T., …Mamas, M. (2021). Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality. European Heart Journal - Quality of Care and Clinical Outcomes, 7(3), 247-256. https://doi.org/10.1093/ehjqcco/qcaa079

Background: Limited data exists on the impact of COVID-19 on national changes in cardiac procedure activity, including patient characteristics and clinical outcomes before and during the COVID-19 pandemic. Methods and Results: All major cardiac pr... Read More about Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality.

Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials (2020)
Journal Article
Mamas. (2020). Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials. Journal of the American College of Cardiology, 1919-1930. https://doi.org/10.1016/j.jacc.2020.08.062

Background Clinical trials change practice in cardiology, and leading them requires research training, mentorship, sponsorship, and networking. Women report challenges in obtaining these opportunities. Objectives The purpose of this review was t... Read More about Trial characteristics associated with the underrepresentation of women as lead authors in heart failure clinical trials.

Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial (2020)
Journal Article
Nathan R., H., Chris, A., Lee, B., A. John, C., David, C., D. Wyn, D., …Alexander T., C. (2020). Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial. Contemporary Clinical Trials Communications, https://doi.org/10.1016/j.cct.2020.106191

Atrial fibrillation (AF) is associated with an increased risk of stroke, enhanced stroke severity, and other comorbidities. However, AF is often asymptomatic, and frequently remains undiagnosed until complications occur. Current screening approaches... Read More about Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial.

Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID-19-related infections, hospital admissions and mortality (2020)
Journal Article
Heald, A. H., Stedman, M., Tian, Z., Wu, P., & Fryer, A. A. (2021). Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID-19-related infections, hospital admissions and mortality. International Journal of Clinical Practice, https://doi.org/10.1111/ijcp.13768

Introduction The rapid spread of the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV26 2/)(COVID-19) virus resulted in governments around the world instigating a range of measures, including mandating the wearing of... Read More about Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID-19-related infections, hospital admissions and mortality.

Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. (2020)
Journal Article
Corp, N., Mansell, G., Stynes, S., Wynne-Jones, G., Morsø, L., Hill, J., & Van Der Windt, D. (2021). Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines. European Journal of Pain, 25(2), https://doi.org/10.1002/ejp.1679

Background and objective: This systematic review synthesised evidence from European neck and low back pain (NLBP) clinical practice guidelines (CPGs) to identify recommended treatment options for use across Europe. Databases and Data Treatment: Compr... Read More about Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines..

Factors associated with adverse COVID-19 outcomes in patients with psoriasis: insights from a global registry-based study (2020)
Journal Article
Mahil, S. K., Dand, N., Mason, K. J., Yiu, Z. Z. . N., Tsakok, T., Meynell, F., …study group, P. (2021). Factors associated with adverse COVID-19 outcomes in patients with psoriasis: insights from a global registry-based study. Journal of Allergy and Clinical Immunology, 147(1), 60-71. https://doi.org/10.1016/j.jaci.2020.10.007

BACKGROUND: The multi-morbid burden and use of systemic immunosuppressants in people with psoriasis may confer greater risk of adverse COVID-19 outcomes but data are limited. OBJECTIVE: Characterize the course of COVID-19 in psoriasis and identify fa... Read More about Factors associated with adverse COVID-19 outcomes in patients with psoriasis: insights from a global registry-based study.

Ethnic differences in mortality and hospital admission rates between Maori, Pacific, and European New Zealanders with type 2 diabetes between 1994 and 2018: a retrospective, population-based, longitudinal cohort study (2020)
Journal Article
Yu, D., Zhao, Z., Osuagwu, U. L., Pickering, K., Baker, J., Cutfield, R., …Simmons, D. (2021). Ethnic differences in mortality and hospital admission rates between Maori, Pacific, and European New Zealanders with type 2 diabetes between 1994 and 2018: a retrospective, population-based, longitudinal cohort study. The Lancet Global Health, 9(2), e209-e217. https://doi.org/10.1016/S2214-109X%2820%2930412-5

Background Type 2 diabetes affects Indigenous and non-European populations disproportionately, including in New Zealand, where long-term temporal trends in cause-specific clinical outcomes between Maori, Pacific, and European people remain unclear.... Read More about Ethnic differences in mortality and hospital admission rates between Maori, Pacific, and European New Zealanders with type 2 diabetes between 1994 and 2018: a retrospective, population-based, longitudinal cohort study.

Excess mortality in England and Wales during the first wave of the COVID-19 pandemic. (2020)
Journal Article
Mamas. (2020). Excess mortality in England and Wales during the first wave of the COVID-19 pandemic. Journal of Epidemiology and Community Health, 213 - 223. https://doi.org/10.1136/jech-2020-214764

BACKGROUND: Deaths during the COVID-19 pandemic result directly from infection and exacerbation of other diseases and indirectly from deferment of care for other conditions, and are socially and geographically patterned. We quantified excess mortalit... Read More about Excess mortality in England and Wales during the first wave of the COVID-19 pandemic..

Fostering excellence in medical education career pathways (2020)
Journal Article
Rees. (2020). Fostering excellence in medical education career pathways. Education for Primary Care, https://doi.org/10.1080/14739879.2020.1827302

High quality medical education requires committed and skilled educators, researchers, and leaders. Capacity building for future educationalists is fundamental in the pursuit of excellence in medical education. Medical education as a discipline is u... Read More about Fostering excellence in medical education career pathways.

Finding the 'right' GP: a qualitative study of the experiences of people with long-COVID (2020)
Journal Article
Kingstone, T., Taylor, A. K., O'Donnell, C. A., Atherton, H., Blane, D. N., & Chew-Graham, C. (2020). Finding the 'right' GP: a qualitative study of the experiences of people with long-COVID. British Journal of General Practice Open (BJGP Open), 4(5), https://doi.org/10.3399/bjgpopen20X101143

BACKGROUND: An unknown proportion of people who had an apparently mild COVID-19 infection continue to suffer with persistent symptoms, including chest pain, shortness of breath, muscle and joint pains, headaches, cognitive impairment ('brain fog'), a... Read More about Finding the 'right' GP: a qualitative study of the experiences of people with long-COVID.

A prognostic model predicted deterioration in health-related quality of life in older patients with multimorbidity and polypharmacy (2020)
Journal Article
(2020). A prognostic model predicted deterioration in health-related quality of life in older patients with multimorbidity and polypharmacy. Journal of Clinical Epidemiology, https://doi.org/10.1016/j.jclinepi.2020.10.006

OBJECTIVE: To develop and validate a prognostic model to predict deterioration in health-related quality of life (dHRQoL) in older general practice patients with at least one chronic condition and one chronic prescription. STUDY DESIGN AND SETTING: W... Read More about A prognostic model predicted deterioration in health-related quality of life in older patients with multimorbidity and polypharmacy.

Visual recovery after small incision lenticule extraction (SMILE) in relation to pre-operative spherical equivalent (2020)
Journal Article
Tay, E., & Bajpai, R. (2021). Visual recovery after small incision lenticule extraction (SMILE) in relation to pre-operative spherical equivalent. Graefe's Archive for Clinical and Experimental Ophthalmology, 259(4), 1053–1060. https://doi.org/10.1007/s00417-020-04954-8

Purpose To assess visual recovery after small incision lenticule extraction (SMILE) in relation to pre-operative spherical equivalent. Methods Two hundred fourteen eyes of 107 patients were enrolled. Following surgery, patients were examined pre-oper... Read More about Visual recovery after small incision lenticule extraction (SMILE) in relation to pre-operative spherical equivalent.

Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis. (2020)
Journal Article
(2020). Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health, https://doi.org/10.3390/ijerph17207380

The Outcome Measures in Rheumatology workgroup (OMERACT), together with the Osteoarthritis Research Society International (OARSI) developed the OMERACT-OARSI responder criteria. These criteria are used to determine if a patient with osteoarthritis (O... Read More about Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis..