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All Outputs (553)

Exploring the physical, psychological and social well-being of people with rheumatoid arthritis during the coronavirus pandemic: a single-centre, longitudinal, qualitative interview study in the UK (2022)
Journal Article
Brooks, M., Hassell, A., Ryan, S., Campbell, P., Paskins, Z., Hider, S., …Manning, F. (2022). Exploring the physical, psychological and social well-being of people with rheumatoid arthritis during the coronavirus pandemic: a single-centre, longitudinal, qualitative interview study in the UK. BMJ Open, 12, Article e056555

Objective Rheumatoid arthritis (RA) is an autoimmune, inflammatory, systemic condition that requires specific drug treatment to suppress disease activity and prevent joint deformity. To manage the ongoing symptoms of joint pain and fatigue patients a... Read More about Exploring the physical, psychological and social well-being of people with rheumatoid arthritis during the coronavirus pandemic: a single-centre, longitudinal, qualitative interview study in the UK.

Investigating the links between diagnostic uncertainty, emotional exhaustion, and turnover intention in General Practitioners working in the United Kingdom (2022)
Journal Article
Chew-Graham. (2022). Investigating the links between diagnostic uncertainty, emotional exhaustion, and turnover intention in General Practitioners working in the United Kingdom. Frontiers in Psychiatry, https://doi.org/10.3389/fpsyt.2022.936067

Background: General Practitioners (GPs) report high levels of burnout, job dissatisfaction, and turnover intention. The complexity of presenting problems to general practice makes diagnostic uncertainty a common occurrence that has been linked to bur... Read More about Investigating the links between diagnostic uncertainty, emotional exhaustion, and turnover intention in General Practitioners working in the United Kingdom.

Diagnostic Models Combining Clinical Information, Ultrasound and Biochemical Markers for Ovarian Cancer: Cochrane Systematic Review and Meta-Analysis. (2022)
Journal Article
(2022). Diagnostic Models Combining Clinical Information, Ultrasound and Biochemical Markers for Ovarian Cancer: Cochrane Systematic Review and Meta-Analysis. Cancers, https://doi.org/10.3390/cancers14153621

BACKGROUND: Ovarian cancer (OC) is a diagnostic challenge, with the majority diagnosed at late stages. Existing systematic reviews of diagnostic models either use inappropriate meta-analytic methods or do not conduct statistical comparisons of models... Read More about Diagnostic Models Combining Clinical Information, Ultrasound and Biochemical Markers for Ovarian Cancer: Cochrane Systematic Review and Meta-Analysis..

Impact of Multisite artery disease on Clinical Outcomes After Percutaneous Coronary Intervention: An Analysis from the e-Ultimaster Registry. (2022)
Journal Article
Mamas. (2022). Impact of Multisite artery disease on Clinical Outcomes After Percutaneous Coronary Intervention: An Analysis from the e-Ultimaster Registry. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcac043

BACKGROUND: multisite artery disease is considered a 'malignant' type of atherosclerotic disease associated with an increased cardiovascular risk, but the impact of multisite artery disease on clinical outcomes after percutaneous coronary interventio... Read More about Impact of Multisite artery disease on Clinical Outcomes After Percutaneous Coronary Intervention: An Analysis from the e-Ultimaster Registry..

Knowledge, Attitude, and Practices of Pregnant Women Towards COVID-19: An On-site Cross-sectional Survey (2022)
Journal Article
Singh, C., Shahnaz, G., Bajpai, R., & Sundar, J. (2022). Knowledge, Attitude, and Practices of Pregnant Women Towards COVID-19: An On-site Cross-sectional Survey. Cureus, 14(7), Article ARTN e27259. https://doi.org/10.7759/cureus.27259

Objective: To assess the knowledge, attitude, and practices (KAP) of pregnant women towards coronavirus disease 2019 (COVID-19). Methods: This on-site cross-sectional survey was conducted in the antenatal and fetal medicine clinics in a tertiary c... Read More about Knowledge, Attitude, and Practices of Pregnant Women Towards COVID-19: An On-site Cross-sectional Survey.

Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial (2022)
Journal Article
Hill, J. C., Garvin, S., Bromley, K., Saunders, B., Kigozi, J., Cooper, V., …Foster, N. E. (2022). Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial. The Lancet Rheumatology, 4(9), e591 - e602. https://doi.org/10.1016/S2665-9913%2822%2900159-X

Background Risk-based stratified care shows clinical effectiveness and cost-effectiveness versus usual primary care for non-specific low back pain but is untested for other common musculoskeletal disorders. We aimed to test the clinical effectiveness... Read More about Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial.

Hospital procedural volume and outcomes with catheter-directed intervention for pulmonary embolism: a nationwide analysis. (2022)
Journal Article
Mamas. (2022). Hospital procedural volume and outcomes with catheter-directed intervention for pulmonary embolism: a nationwide analysis. https://doi.org/10.1093/ehjacc/zuac082

AIMS: There is limited data on the association between hospital catheter-directed intervention (CDI) volume and outcomes among patients with acute pulmonary embolism (PE). METHODS AND RESULTS: The Nationwide Readmissions Database years 2016-2019 was... Read More about Hospital procedural volume and outcomes with catheter-directed intervention for pulmonary embolism: a nationwide analysis..

Patient feedback on hospital pharmacists’ consultation skills: A feasibility study using the Interpersonal Skills Questionnaire (ISQ) (2022)
Journal Article
Al-Jabr, H., Twigg, M. J., Katangwe-Chigamba, T., Saadvandi, R., & Desborough, J. A. (2022). Patient feedback on hospital pharmacists’ consultation skills: A feasibility study using the Interpersonal Skills Questionnaire (ISQ). PloS one, 17(7), https://doi.org/10.1371/journal.pone.0268544

Background Improvement in practitioners’ consultation skills (CSs) can be driven by patient feedback, however, to date, no study has been conducted with reference to pharmacy consultations. The Interpersonal Skills Questionnaire (ISQ) is potentially... Read More about Patient feedback on hospital pharmacists’ consultation skills: A feasibility study using the Interpersonal Skills Questionnaire (ISQ).

Influence of the Danish Co-morbidity Index Score on the Treatment and Outcomes of 2.5 Million Patients Admitted With Acute Myocardial Infarction in the United States. (2022)
Journal Article
Mamas, M., & Mallen, C. (2022). Influence of the Danish Co-morbidity Index Score on the Treatment and Outcomes of 2.5 Million Patients Admitted With Acute Myocardial Infarction in the United States. American Journal of Cardiology, https://doi.org/10.1016/j.amjcard.2022.06.008

This study aimed to determine the association between the Danish Co-morbidity Index for Acute Myocardial Infarction (DANCAMI) and restricted DANCAMI (rDANCAMI) scores and clinical outcomes in patients hospitalized with AMI. Using the National Inpatie... Read More about Influence of the Danish Co-morbidity Index Score on the Treatment and Outcomes of 2.5 Million Patients Admitted With Acute Myocardial Infarction in the United States..

Monitoring residual kidney function in haemodialysis patients using timed urine collections: validation of the use of estimated blood results to calculate GFR (2022)
Journal Article
Lindley, E., Keane, D., Belcher, J., Fernandes Da Silva Jeffcoat, N., Davies, S., & trial investigators, B. (2022). Monitoring residual kidney function in haemodialysis patients using timed urine collections: validation of the use of estimated blood results to calculate GFR. Physiological Measurement, 43(8), Article 08NT01. https://doi.org/10.1088/1361-6579/ac80e8

OBJECTIVE: With growing recognition of the benefits of preserving residual kidney function (RKF) and use of incremental treatment regimes, the incentive to measure residual clearance in haemodialysis patients is increasing. Interdialytic urine collec... Read More about Monitoring residual kidney function in haemodialysis patients using timed urine collections: validation of the use of estimated blood results to calculate GFR.

Digital health in older adults for the prevention and management of cardiovascular diseases and frailty. A clinical consensus statement from the ESC Council for Cardiology Practice/Taskforce on Geriatric Cardiology, the ESC Digital Health Committee and the ESC Working Group on e-Cardiology (2022)
Journal Article
Mamas, M., Guasti, L., Dilaveris, P., Richter, D., Christodorescu, R., Lumens, J., …Cowie, M. R. (2022). Digital health in older adults for the prevention and management of cardiovascular diseases and frailty. A clinical consensus statement from the ESC Council for Cardiology Practice/Taskforce on Geriatric Cardiology, the ESC Digital Health Committee and the ESC Working Group on e-Cardiology. ESC Heart Failure, 9(5), 2808-2822. https://doi.org/10.1002/ehf2.14022

Digital health technology is receiving increasing attention in cardiology. The rise of accessibility of digital health tools including wearable technologies and smart phone applications used in medical practice has created a new era in healthcare. Th... Read More about Digital health in older adults for the prevention and management of cardiovascular diseases and frailty. A clinical consensus statement from the ESC Council for Cardiology Practice/Taskforce on Geriatric Cardiology, the ESC Digital Health Committee and the ESC Working Group on e-Cardiology.

Incidence and 1-year outcome of periprocedural myocardial infarction following cardiac surgery: are the Universal Definition and Society for Cardiovascular Angiography and Intervention criteria fit for purpose? (2022)
Journal Article
Mamas. (2022). Incidence and 1-year outcome of periprocedural myocardial infarction following cardiac surgery: are the Universal Definition and Society for Cardiovascular Angiography and Intervention criteria fit for purpose?. European Journal of Cardio-Thoracic Surgery, https://doi.org/10.1093/ejcts/ezac019

OBJECTIVES: The diagnosis and clinical implications of periprocedural myocardial infarction (PPMI) following coronary artery bypass grafting (CABG) are contentious, especially the importance of PPMI in the interpretation of trial data. METHODS: Conse... Read More about Incidence and 1-year outcome of periprocedural myocardial infarction following cardiac surgery: are the Universal Definition and Society for Cardiovascular Angiography and Intervention criteria fit for purpose?.

Effects of Shoe-Stiffening Inserts on Lower Limb Kinematics in Individuals with First Metatarsophalangeal Joint Osteoarthritis. (2022)
Journal Article
Roddy, E., McClelland, J. A., Allan, J. J., Auhl, M., Buldt, A. K., Landorf, K. B., …Munteanu, S. E. (2022). Effects of Shoe-Stiffening Inserts on Lower Limb Kinematics in Individuals with First Metatarsophalangeal Joint Osteoarthritis. Arthritis Care and Research, 74(11), 1849-1856. https://doi.org/10.1002/acr.24647

OBJECTIVE: To examine the effects of shoe-stiffening inserts on lower limb kinematics in individuals with first metatarsophalangeal (MTP) joint osteoarthritis (OA). METHODS: Forty-eight individuals with radiographically confirmed first MTP joint... Read More about Effects of Shoe-Stiffening Inserts on Lower Limb Kinematics in Individuals with First Metatarsophalangeal Joint Osteoarthritis..

Can omega-3 fatty acids and vitamin E co-supplementation affect obesity indices? (2022)
Journal Article
Musazadeh, V., Tandorost, A., Zarezadeh, M., Jafarzadeh, J., Ghavami, Z., Jamilian, P., & Ostadrahimi, A. (2023). Can omega-3 fatty acids and vitamin E co-supplementation affect obesity indices?. International Journal for Vitamin and Nutrition Research, 93(5), 471-480. https://doi.org/10.1024/0300-9831/a000757

Background: Studies have shown that vitamin E as an antioxidant protects omega-3 fatty acids (FAs) from oxidation. Several studies have evaluated the effect of omega-3 FAs and vitamin E co-supplementation on obesity indices; however, the results are... Read More about Can omega-3 fatty acids and vitamin E co-supplementation affect obesity indices?.

Metformin use and the risk of total knee replacement among diabetic patients: a propensity-score-matched retrospective cohort study. (2022)
Journal Article
Lai, F., Yip, B., Hunter, D., Rabago, D., Mallen, C., Yeoh, E., …Sit, R. (2022). Metformin use and the risk of total knee replacement among diabetic patients: a propensity-score-matched retrospective cohort study. Scientific reports, 11571 - ?. https://doi.org/10.1038/s41598-022-15871-7

Metformin has been shown to modulate meta-inflammation, an important pathogenesis in knee osteoarthritis (OA). The study aimed to test the association between regular metformin use with total knee replacement (TKR) in patients with diabetes. This is... Read More about Metformin use and the risk of total knee replacement among diabetic patients: a propensity-score-matched retrospective cohort study..

Safety and efficacy of transcatheter aortic valve implantation in stenotic bicuspid aortic valve compared to tricuspid aortic valve: a systematic review and meta-analysis. (2022)
Journal Article
Zghouzi, M., Osman, H., Ullah, W., Suleiman, A., Razvi, P., Abdalrazzak, M., …Chadi Alraies, M. (2022). Safety and efficacy of transcatheter aortic valve implantation in stenotic bicuspid aortic valve compared to tricuspid aortic valve: a systematic review and meta-analysis. Expert Review of Cardiovascular Therapy, 581 - 588. https://doi.org/10.1080/14779072.2022.2094368

BACKGROUND: Transcatheter aortic valve implantation (TAVI) has emerged as a safe and effective alternative to surgical replacement for tricuspid aortic valve (TAV) stenosis. However, utilization of TAVI for aortic stenosis in bicuspid aortic valve (B... Read More about Safety and efficacy of transcatheter aortic valve implantation in stenotic bicuspid aortic valve compared to tricuspid aortic valve: a systematic review and meta-analysis..

Management of anxiety disorders among children and adolescents in UK primary care: A cohort study. (2022)
Journal Article
Chew-Graham. (2022). Management of anxiety disorders among children and adolescents in UK primary care: A cohort study. Journal of Affective Disorders, 270 - 277. https://doi.org/10.1016/j.jad.2022.07.002

BACKGROUND: Anxiety disorders are common in childhood and adolescence but evidence-based guidance on their management is limited in the UK. In the absence of guidelines, we examined what treatment young people with anxiety disorders receive in primar... Read More about Management of anxiety disorders among children and adolescents in UK primary care: A cohort study..

Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM) (2022)
Presentation / Conference
Mason, K., Bailey, J., Heron, N., Marshall, M., Achana, F., Chen, Y., …Jordan, K. (2022, July). Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM). Paper presented at SAPC ASM 2022 - UCLan 50th Annual Scientific Meeting, University of Central Lancashire, UK

Background: Patients with painful musculoskeletal conditions have an increased risk of developing cancer, but less is known about whether this impacts on the longer-term cancer prognosis. This study aims to determine whether patients with painful mus... Read More about Musculoskeletal pain and its impact on rates of hospitalisation and mortality in cancer: a linked electronic health record cohort study (MSKCOM).