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Does Exercise Reduce Depressive Symptoms? Commentary Review on Efficacy, Mechanisms and Implementation (2022)
Journal Article
Campbell, P. (2022). Does Exercise Reduce Depressive Symptoms? Commentary Review on Efficacy, Mechanisms and Implementation. Anxiety and Depression Journal, 3(1), 1-6

This commentary review evaluates current review and meta-analysis evidence on the association between exercise and depression. Collectively this evidence demonstrates a clear and robust effect of depressive symptom reduction as a result of exercise,... Read More about Does Exercise Reduce Depressive Symptoms? Commentary Review on Efficacy, Mechanisms and Implementation.

Influenza vaccine improves cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis. (2022)
Journal Article
Mamas. (2022). Influenza vaccine improves cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis. Travel Medicine and Infectious Disease, 102311 - ?. https://doi.org/10.1016/j.tmaid.2022.102311

BACKGROUND: There are inconsistent data on the clinical benefit of the influenza vaccine on cardiovascular outcomes in patients with coronary artery disease (CAD). Therefore, the aim of our study was to evaluate the effect of the influenza vaccine on... Read More about Influenza vaccine improves cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis..

Behavioural Activation for Social IsoLation (BASIL+) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trial. (2022)
Journal Article
Chew-Graham. (2022). Behavioural Activation for Social IsoLation (BASIL+) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trial. PloS one, e0263856 - ?. https://doi.org/10.1371/journal.pone.0263856

Introduction Depression is a leading mental health problem worldwide. People with long-term conditions are at increased risk of experiencing depression. The COVID-19 pandemic led to strict social restrictions being imposed across the UK population... Read More about Behavioural Activation for Social IsoLation (BASIL+) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trial..

TREATMENT ACCEPTABILITY AND ENGAGEMENT AMONGST PATIENTS ON ORAL AND INTRAVENOUS BISPHOSPHONATES: A QUALITATIVE STUDY (2022)
Presentation / Conference
Narayanasamy, M., Bishop, S., Sahota, O., Leonardi-Bee, J., Paskins, Z., Gittoes, N., …Cottrell, E. (2022, March). TREATMENT ACCEPTABILITY AND ENGAGEMENT AMONGST PATIENTS ON ORAL AND INTRAVENOUS BISPHOSPHONATES: A QUALITATIVE STUDY. Poster presented at World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2022), Virtual

Objective: To explore treatment acceptability and engagement amongst patients prescribed oral and intravenous bisphosphonate treatment regimens for the prevention of osteoporotic fragility fractures. Methods: Semistructured interviews were conduct... Read More about TREATMENT ACCEPTABILITY AND ENGAGEMENT AMONGST PATIENTS ON ORAL AND INTRAVENOUS BISPHOSPHONATES: A QUALITATIVE STUDY.

Comparative Effectiveness of Statins on Non-HDL Cholesterol by Type and Intensity in People with Diabetes and at Risk of Cardiovascular Disease: Systematic Review and Network Meta-Analysis (2022)
Journal Article
Hodkinson, A., Tsimpida, D., Kontopantelis, E., Rutter, M. K., Mamas, M., & Panagioti, M. (2022). Comparative Effectiveness of Statins on Non-HDL Cholesterol by Type and Intensity in People with Diabetes and at Risk of Cardiovascular Disease: Systematic Review and Network Meta-Analysis. BMJ, 376, Article e067731. https://doi.org/10.1136/bmj-2021-067731

Objective: To compare the efficacy of different statin treatments by intensity on levels of non-high density lipoprotein cholesterol (non-HDL-C) for the prevention of cardiovascular disease in people with diabetes. Design: Systematic review and ne... Read More about Comparative Effectiveness of Statins on Non-HDL Cholesterol by Type and Intensity in People with Diabetes and at Risk of Cardiovascular Disease: Systematic Review and Network Meta-Analysis.

Identification of undiagnosed atrial fibrillation using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI) in primary care: a multi-centre randomised controlled trial in England (2022)
Journal Article
Hill, N. R., Groves, L., Dickerson, C., Ochs, A., Pang, D., Lawton, S., …Cohen, A. T. (2022). Identification of undiagnosed atrial fibrillation using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI) in primary care: a multi-centre randomised controlled trial in England. European Heart Journal, S111 - S111. https://doi.org/10.1093/ehjdh/ztac009

Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study (2022)
Journal Article
Närhi, F., Moonesinghe, R., Shenkin, S. D., Drake, T. M., Mulholland, R. H., Donegan, C., …Docherty, A. B. (2022). Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study. The Lancet Digital Health, 4(4), e220 - e234. https://doi.org/10.1016/S2589-7500%2822%2900018-8

Background Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY trial p... Read More about Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study.

Accuracy of placement of ultrasound-guided corticosteroid injection for subacromial pain (impingement) syndrome does not influence pain and function: secondary analysis of a randomised controlled trial (2022)
Journal Article
Chean, C. S., Raval, P., Ogollah, R. O., Hall, A., Roddy, E., & Foster, N. E. (2022). Accuracy of placement of ultrasound-guided corticosteroid injection for subacromial pain (impingement) syndrome does not influence pain and function: secondary analysis of a randomised controlled trial. Musculoskeletal Care, 20(4), 831-838. https://doi.org/10.1002/msc.1634

Abstract Objectives: To investigate whether the accuracy of placement of ultrasound-guided (US-guided) corticosteroid injections for subacromial pain (impingement) syndrome (SAPS) influences pain and function outcomes. Methods: This was a seconda... Read More about Accuracy of placement of ultrasound-guided corticosteroid injection for subacromial pain (impingement) syndrome does not influence pain and function: secondary analysis of a randomised controlled trial.

FFR- Versus Angiography-Guided Revascularization for Nonculprit Stenosis in STEMI and Multivessel Disease: A Network Meta-Analysis. (2022)
Journal Article
Mamas. (2022). FFR- Versus Angiography-Guided Revascularization for Nonculprit Stenosis in STEMI and Multivessel Disease: A Network Meta-Analysis. JACC. Cardiovascular interventions, 656 - 666. https://doi.org/10.1016/j.jcin.2022.01.002

OBJECTIVES: The aim of this study was to examine the efficacy and safety of fractional flow reserve (FFR)-guided versus angiography-guided approaches for nonculprit stenosis among patients with acute ST-segment elevation myocardial infarction (STEMI)... Read More about FFR- Versus Angiography-Guided Revascularization for Nonculprit Stenosis in STEMI and Multivessel Disease: A Network Meta-Analysis..

implementation of an intensive second language reading intervention program for Arabic L1 learners of English as a foreign language (2022)
Journal Article
Joan Oakley, M., Kormos, J., & McCray, G. (2022). implementation of an intensive second language reading intervention program for Arabic L1 learners of English as a foreign language. Instructed Second Language Acquisition, 6(1), https://doi.org/10.1558/isla.18885

The aim of this study was to investigate the effects of focused reading interventions on the eye movement patterns and reading scores of second language (L2) learners. We compared two groups of proficiency matched Arabic L2 learners before and after... Read More about implementation of an intensive second language reading intervention program for Arabic L1 learners of English as a foreign language.

Long‐Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study (2022)
Journal Article
Jordan, K. P., Rathod‐Mistry, T., Bailey, J., Chen, Y., Clarson, L., Denaxas, S., …Mamas, M. A. (2022). Long‐Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study. Journal of the American Heart Association, 11(7), Article e023146. https://doi.org/10.1161/JAHA.121.023146

Background Most adults presenting with chest pain will not receive a diagnosis and be recorded with unattributed chest pain. The objective was to assess if they have increased risk of cardiovascular disease compared with those with noncoronary chest... Read More about Long‐Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study.

Opioid use prior to total knee replacement: comparative analysis of trends in England and Sweden (2022)
Journal Article
Yu, D., Hellberg, C., Appleyard, T., Dell'Isola, A., Thomas, G. E. R., Turkiewicz, A., …Peat, G. (2022). Opioid use prior to total knee replacement: comparative analysis of trends in England and Sweden. Osteoarthritis and Cartilage, 30(6), 815-822. https://doi.org/10.1016/j.joca.2022.02.621

Objectives To describe and compare trends in the frequency of opioid prescribing/dispensing in English and Swedish patients with osteoarthritis prior to total knee replacement (TKR). Methods 49,043 patients from an English national database (Clinical... Read More about Opioid use prior to total knee replacement: comparative analysis of trends in England and Sweden.

The Impact of Intracoronary Imaging on PCI Outcomes in Cases Utilising Rotational Atherectomy: An Analysis of 8,417 Rotational Atherectomy Cases from the British Cardiovascular Intervention Society Database. (2022)
Journal Article
Protty, M. B., Gallagher, S., Sharp, A. S., Farooq, V., Egred, M., O’Kane, P., …Kinnaird, T. (2022). The Impact of Intracoronary Imaging on PCI Outcomes in Cases Utilising Rotational Atherectomy: An Analysis of 8,417 Rotational Atherectomy Cases from the British Cardiovascular Intervention Society Database. Journal of Interventional Cardiology, 5879187 - ?. https://doi.org/10.1155/2022/5879187

INTRODUCTION: There is increasing evidence supporting the use of intracoronary imaging to optimize the outcomes of percutaneous coronary intervention (PCI). However, there are no studies examining the impact of imaging on PCI outcomes in cases utilis... Read More about The Impact of Intracoronary Imaging on PCI Outcomes in Cases Utilising Rotational Atherectomy: An Analysis of 8,417 Rotational Atherectomy Cases from the British Cardiovascular Intervention Society Database..

A clinical tool to identify older women with back pain at high risk of osteoporotic vertebral fractures (Vfrac): a population-based cohort study with exploratory economic evaluation (2022)
Journal Article
Paskins. (2022). A clinical tool to identify older women with back pain at high risk of osteoporotic vertebral fractures (Vfrac): a population-based cohort study with exploratory economic evaluation. Age and ageing, https://doi.org/10.1093/ageing/afac031

Background: Osteoporotic vertebral fractures (OVFs) identify people at high risk of future fractures, but despite this, less than a third come to clinical attention. The objective of this study was to develop a clinical tool to aid healthcare profess... Read More about A clinical tool to identify older women with back pain at high risk of osteoporotic vertebral fractures (Vfrac): a population-based cohort study with exploratory economic evaluation.

Diagnostic Delay in Pediatric Inflammatory Bowel Disease: A Systematic Review (2022)
Journal Article
Matoi, S., Hay, C., Baines, L., Saunders, B., Farmer, A., Cross, E., …Prior, J. (2022). Diagnostic Delay in Pediatric Inflammatory Bowel Disease: A Systematic Review. Digestive Diseases and Sciences, 67, 5444–5454. https://doi.org/10.1007/s10620-022-07452-5

Introduction Delays in diagnosing pediatric inflammatory bowel disease (IBD) are common, but the extent of this delay remains unclear due to variations in reported time-periods between studies. The objectives of this systematic review were to examine... Read More about Diagnostic Delay in Pediatric Inflammatory Bowel Disease: A Systematic Review.

The clinical effectiveness of a physiotherapy delivered physical and psychological group intervention for older adults with neurogenic claudication: the BOOST randomised controlled trial. (2022)
Journal Article
Mallen. (2022). The clinical effectiveness of a physiotherapy delivered physical and psychological group intervention for older adults with neurogenic claudication: the BOOST randomised controlled trial. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, https://doi.org/10.1093/gerona/glac063

BACKGROUND: Neurogenic claudication (NC) is a debilitating spinal condition affecting older adults' mobility and quality of life. METHODS: A randomised controlled trial of 438 participants evaluated the effectiveness of a physical and psychological g... Read More about The clinical effectiveness of a physiotherapy delivered physical and psychological group intervention for older adults with neurogenic claudication: the BOOST randomised controlled trial..

The impact of nursing staff education on diabetes inpatient glucose management: a pilot cluster randomised controlled trial (2022)
Journal Article
Piya, M., Zarora, R., Yu, D., Fletcher, T., Myint, K., & Simmons, D. (2022). The impact of nursing staff education on diabetes inpatient glucose management: a pilot cluster randomised controlled trial. BMC Endocrine Disorders, 22, Article 61. https://doi.org/10.1186/s12902-022-00975-y

Background: An increasing number of patients in hospital have diabetes, with most of them cared for by non-specialist staff. The effect of diabetes education for staff on patient outcomes, as well as the most effective method of staff education is un... Read More about The impact of nursing staff education on diabetes inpatient glucose management: a pilot cluster randomised controlled trial.

COMPLEX, HIGH-RISK BUT INDICATED PERCUTANEOUS CORONARY INTERVENTIONS (CHIP) TYPES AND OUTCOMES AMONG DIFFERENT AGE GROUPS. AN INSIGHT FROM A NATIONAL REGISTRY (2022)
Journal Article
Rashid, & Mamas. (2022). COMPLEX, HIGH-RISK BUT INDICATED PERCUTANEOUS CORONARY INTERVENTIONS (CHIP) TYPES AND OUTCOMES AMONG DIFFERENT AGE GROUPS. AN INSIGHT FROM A NATIONAL REGISTRY. Journal of the American College of Cardiology, 855 - 855. https://doi.org/10.1016/s0735-1097%2822%2901846-0

Background: Studies looking at Complex, High-risk but Indicated Percutaneous coronary intervention (CHiP) type and outcomes among the octogenarian are limited. Methods: Data on PCI for stable angina from 1st January 2006 to 31st December 2017 was obt... Read More about COMPLEX, HIGH-RISK BUT INDICATED PERCUTANEOUS CORONARY INTERVENTIONS (CHIP) TYPES AND OUTCOMES AMONG DIFFERENT AGE GROUPS. AN INSIGHT FROM A NATIONAL REGISTRY.