All Outputs (623)

Outcomes of Cochlear implantation in early‐deafened patients with Waardenburg syndrome: A systematic review and narrative synthesis (2023)
Journal Article
Lovett, A., Eastwood, M., Metcalfe, C., Muzaffar, J., Monksfield, P., & Bance, M. (in press). Outcomes of Cochlear implantation in early‐deafened patients with Waardenburg syndrome: A systematic review and narrative synthesis. Laryngoscope Investigative Otolaryngology, https://doi.org/10.1002/lio2.1110

Objective: This systematic review aims to establish the expected hearing and speech outcomes following cochlear implantation (CI) in patients with profound congenital deafness secondary to Waardenburg syndrome (WS). Methods: A systematic review of th... Read More about Outcomes of Cochlear implantation in early‐deafened patients with Waardenburg syndrome: A systematic review and narrative synthesis.

Prevalence and outcomes of type 2 myocardial infarction in patients with cancer: A retrospective analysis from the National Inpatient Sample dataset. (2023)
Journal Article
Castaldi, G., Bharadwaj, A. S., Bagur, R., Van Spall, H. G. C., Kobo, O., & Mamas, M. A. (in press). Prevalence and outcomes of type 2 myocardial infarction in patients with cancer: A retrospective analysis from the National Inpatient Sample dataset. International Journal of Cardiology, 389, Article 131154. https://doi.org/10.1016/j.ijcard.2023.131154

This study aimed to investigate the prevalence, clinical characteristics and outcomes of type 2 myocardial infarction (T2AMI) in patients with versus without cancer. All hospitalizations with a primary discharge diagnosis of T2AMI were stratified acc... Read More about Prevalence and outcomes of type 2 myocardial infarction in patients with cancer: A retrospective analysis from the National Inpatient Sample dataset..

Infographic. Getting to the bottom of saddle sores: an infographic. (2023)
Journal Article
Napier, D. N., Rankin, A., & Heron, N. (in press). Infographic. Getting to the bottom of saddle sores: an infographic. British Journal of Sports Medicine, bjsports-2023-106911. https://doi.org/10.1136/bjsports-2023-106911

Saddle sores are skin lesions that affect the area of skin in contact with the bicycle saddle and can prove troublesome for cyclists.1 Friction and compression of the skin can lead to chafing,2 redness and infections such as folliculitis and furuncul... Read More about Infographic. Getting to the bottom of saddle sores: an infographic..

Health Care Professionals’ Perspectives of Early Intervention in Psychosis Services: A Qualitative Study (2023)
Presentation / Conference
Rickett, M., Kingstone, T., Gupta, V., Shiers, D., French, P., Lennox, B., & Chew-Graham, C. (2023, July). Health Care Professionals’ Perspectives of Early Intervention in Psychosis Services: A Qualitative Study. Poster presented at RCPsych International Congress 2023, Liverpool, England, UK

Aims An Early Intervention in Psychosis (EIP) service offers treatment in the community to people with a first episode of psychosis. EIP is meant to be given for three years; after this time, those who are well are discharged to their GP, while thos... Read More about Health Care Professionals’ Perspectives of Early Intervention in Psychosis Services: A Qualitative Study.

UK research data resources based on primary care electronic health records: review and summary for potential users (2023)
Journal Article
Edwards, L., Pickett, J., Ashcroft, D. M., Dambha-Miller, H., Majeed, A., Mallen, C., …MacLeod, J. (2023). UK research data resources based on primary care electronic health records: review and summary for potential users. British Journal of General Practice Open (BJGP Open), https://doi.org/10.3399/BJGPO.2023.0057

To describe the current landscape of UK electronic health record (EHR) databases and considerations of access and use of these resources relevant to researchers. Narrative review DATA SOURCES: Information was collected from the Health Data Research I... Read More about UK research data resources based on primary care electronic health records: review and summary for potential users.

Test-retest reliability of pain VAS/NRS, stiffness VAS/NRS, HAQ-DI and mHAQ in polymyalgia rheumatica: An OMERACT study (2023)
Journal Article
Leung, J. L., Twohig, H., Muller, S., Maxwell, L., Mackie, S. L., Neill, L. M., & Owen, C. E. (2023). Test-retest reliability of pain VAS/NRS, stiffness VAS/NRS, HAQ-DI and mHAQ in polymyalgia rheumatica: An OMERACT study. Seminars in Arthritis and Rheumatism, 62, 152239. https://doi.org/10.1016/j.semarthrit.2023.152239

Objective To examine the test-retest reliability of four measurement instruments in polymyalgia rheumatica (PMR): pain severity visual analogue scale (VAS) / numerical rating score (NRS), stiffness severity VAS/NR... Read More about Test-retest reliability of pain VAS/NRS, stiffness VAS/NRS, HAQ-DI and mHAQ in polymyalgia rheumatica: An OMERACT study.

Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis (2023)
Journal Article
Manning, F. M., Mughal, F., Ismail, H. A. S. M., Baines, L. M., Chew-Graham, C. A., Paskins, Z., & Prior, J. A. (2023). Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis. British Journal of General Practice (BJGP), 73(735), e735-e743. https://doi.org/10.3399/BJGP.2023.0035

Background: Increase in presentations of self-harm to primary care, a risk factor of suicide, has led to a growing interest in identifying at-risk populations. Aim: To examine whether osteoporosis or fractures are risk factors for self-harm, sui... Read More about Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis.

Development and validation of a short form psychometric tool assessing the caregiving Challenge of Living with Cystic Fibrosis (CLCF-SF) in a child. (2023)
Journal Article
McCray, G., Hope, H. F., Glasscoe, C., Hill, J., Quittner, A., Southern, K. W., …Lancaster, G. A. (in press). Development and validation of a short form psychometric tool assessing the caregiving Challenge of Living with Cystic Fibrosis (CLCF-SF) in a child. Psychology & Health, 1-23. https://doi.org/10.1080/08870446.2023.2231489

Caring for a child with cystic fibrosis (CF) is a rigorous daily commitment for caregivers and treatment burden is a major concern. We aimed to develop and validate a short form version of a 46-item tool assessing the Challenge of Living with Cystic... Read More about Development and validation of a short form psychometric tool assessing the caregiving Challenge of Living with Cystic Fibrosis (CLCF-SF) in a child..

Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome (2023)
Journal Article
Hanna, F., Wu, P., Heald, A., & Fryer, A. (2023). Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome. BMJ, 382, Article e071675. https://doi.org/10.1136/bmj-2022-071675

Gestational diabetes mellitus (GDM) and polycystic ovarian syndrome (PCOS) represent two of the highest risk factors for development of type 2 diabetes mellitus in young women. As these increasingly common conditions generally affect younger women, e... Read More about Diabetes detection in women with gestational diabetes and polycystic ovarian syndrome.

Using the Primary care Academic CollaboraTive to explore the characteristics and healthcare use of older housebound patients in England: protocol for a retrospective observational study and clinician survey (the CHiP study) (2023)
Journal Article
Winn, E., Kissane, M., Merriel, S., Brain, T., Silverwood, V., Whitehead, O., …Duncan, P. (in press). Using the Primary care Academic CollaboraTive to explore the characteristics and healthcare use of older housebound patients in England: protocol for a retrospective observational study and clinician survey (the CHiP study). British Journal of General Practice Open (BJGP Open), 7(4), https://doi.org/10.3399/BJGPO.2023.0114

Older housebound people are an under researched group for whom achieving good primary healthcare can be resource intensive. To describe the characteristics and healthcare use of older (≥65 years) housebound people; explore clinician views on delivery... Read More about Using the Primary care Academic CollaboraTive to explore the characteristics and healthcare use of older housebound patients in England: protocol for a retrospective observational study and clinician survey (the CHiP study).

Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population (2023)
Journal Article
Price, A., Smith, J. R., Mughal, F., Salimi, A., Melendez-Torres, G. J., & Newlove-Delgado, T. (2023). Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population. BMJ Open, 13(7), Article e068184. https://doi.org/10.1136/bmjopen-2022-068184

Introduction: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and adolescents, with an average worldwide prevalence of 5%. Up to 40% of young people continue to experience symptoms into adult... Read More about Protocol for the mixed methods, Managing young people (aged 16–25) with Attention deficit hyperactivity disorder in Primary care (MAP) study: mapping current practice and co-producing guidance to improve healthcare in an underserved population.

Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial (2023)
Journal Article
Farooq, S., Sheikh, S., Dikomitis, L., Haq, M. M. U., Khan, A. J., Sanauddin, N., …Lewis, M. (2023). Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial. BMJ Open, 13(7), e072471. https://doi.org/10.1136/bmjopen-2023-072471

Objectives: In low/middle-income countries (LMICs), more than half of patients with first-episode psychosis initially seek treatment from traditional and religious healers as their first care. This contributes to an excessively long duration of untre... Read More about Traditional healers working with primary care and mental health for early intervention in psychosis in young persons: protocol for the feasibility cluster randomised controlled trial.

Hypertensive disorders of pregnancy. (2023)
Journal Article
Wu, P., Green, M., & Myers, J. (2023). Hypertensive disorders of pregnancy. BMJ, 381, Article e071653. https://doi.org/10.1136/bmj-2022-071653

Hypertensive disorders of pregnancy (HDP) are one of the most commonly occurring complications of pregnancy and include chronic hypertension, gestational hypertension, and pre-eclampsia. New developments in early pregnancy screening to identify women... Read More about Hypertensive disorders of pregnancy..

Creative community groups as catalysts for health and wellbeing: An ethnographic study of arts participation in Stoke-on-Trent (UK) (2023)
Thesis
Fanthome, J. C. (2023). Creative community groups as catalysts for health and wellbeing: An ethnographic study of arts participation in Stoke-on-Trent (UK). (Thesis). Keele University

The role of creative activity for wellbeing is of growing interest, with third sector resources increasingly utilised to prevent the over-medicalisation of social problems. Experiences of community creative participation, however, are not well unders... Read More about Creative community groups as catalysts for health and wellbeing: An ethnographic study of arts participation in Stoke-on-Trent (UK).

Statistical methods for prognostic factor and risk prediction research (2023)
Thesis
Whittle, R. L. (2023). Statistical methods for prognostic factor and risk prediction research. (Thesis). Keele University

Prognosis research is an important part of medical research as it seeks to understand, predict, and improve future outcomes in people with a given disease or health condition. This thesis focuses on the application and development of statistical meth... Read More about Statistical methods for prognostic factor and risk prediction research.

“Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status (2023)
Thesis
Machin, H. E. (2023). “Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status. (Thesis). Keele University

Undocumented Chinese migration to the UK has, in the aftermath of widely publicised events such as the Dover and Morecambe Bay tragedies, triggered significant concern. Since such events, attention has turned to other forms of irregular entry. Yet, u... Read More about “Hot and bitter tears” (辛酸泪): An inquiry into Chinese migrants’ experiences of undocumented status.

Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study (2023)
Thesis
Campbell, L. H. (2023). Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study. (Thesis). Keele University

Background - First Contact Physiotherapists (FCPs) specialise in supporting people who consult with musculoskeletal conditions in National Health Service primary care. Cited FCP role challenges include professional isolation, time demands and changin... Read More about Using Twitter to mobilise knowledge for First Contact Physiotherapists - A qualitative study.

The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin (2023)
Thesis
Sandhu, K. S. (2023). The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin. (Thesis). Keele University

The following thesis began by discussing current controversies surrounding EPC identification then studied the effect of atorvastatin on EPC numbers in bench and bed side studies. Atorvastatin was hypothesised to increase chemokine CXCL-12 its recep... Read More about The role of Endothelial Progenitor Cells in the pleiotropic effects of Atorvastatin.

Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate (2023)
Thesis
Brown-Lyons, A. L. (2023). Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate. (Thesis). Keele University

Background: Inflammation is a major driver, and perhaps cause, of neurodegeneration, suggesting neuroimmunomodulation as a therapeutic strategy. Microglia, the primary mediators of neuroinflammation, switch between three activation states [surveillan... Read More about Neural immune cell responses to clinically relevant ligands of the niacin receptor (Gpr109a): niacin and monomethyl fumarate.

Effect of onset of type 2 diabetes on risks of cardiovascular disease and heart failure among new Zealanders with impaired glucose tolerance over 25 years: tapered-matched landmark analysis (2023)
Journal Article
Yu, D., Qu, B., Levi Osuagwu, U., Pickering, K., Baker, J., Cutfield MBChB, R., …Simmons, D. (2023). Effect of onset of type 2 diabetes on risks of cardiovascular disease and heart failure among new Zealanders with impaired glucose tolerance over 25 years: tapered-matched landmark analysis. Cardiovascular Diabetology, 22(1), Article 163. https://doi.org/10.1186/s12933-023-01871-y

Background This study aimed to examine the association between the incident onset of T2DM and 5- and 10-year risks of CVD and HF in people with IGT identified in primary care in South and West Auckland, New Zealand (NZ) between 1994 and 2019. Met... Read More about Effect of onset of type 2 diabetes on risks of cardiovascular disease and heart failure among new Zealanders with impaired glucose tolerance over 25 years: tapered-matched landmark analysis.