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Intensive glucose control and the clinical paradox of transient progression of diabetic retinopathy: Prioritising the relevance of eye screening intervals (2024)
Journal Article
Jacob, S., & Varughese, G. I. (in press). Intensive glucose control and the clinical paradox of transient progression of diabetic retinopathy: Prioritising the relevance of eye screening intervals. Journal of the Royal College of Physicians of Edinburgh, https://doi.org/10.1177/14782715241254873

The paradoxical early worsening of diabetic retinopathy with optimisation of glycaemic control is well recognised. Patients with type 2 diabetes mellitus with R0M0 grading at eye screening with enhanced glycaemic control and progression of diabetic r... Read More about Intensive glucose control and the clinical paradox of transient progression of diabetic retinopathy: Prioritising the relevance of eye screening intervals.

Barriers and facilitators of self‐management of diabetes amongst people experiencing socioeconomic deprivation: A systematic review and qualitative synthesis (2024)
Journal Article
Woodward, A., Walters, K., Davies, N., Nimmons, D., Protheroe, J., Chew‐Graham, C. A., …Armstrong, M. (2024). Barriers and facilitators of self‐management of diabetes amongst people experiencing socioeconomic deprivation: A systematic review and qualitative synthesis. Health Expectations, 27(3), Article e14070. https://doi.org/10.1111/hex.14070

Background: The number of people living with diabetes is rising worldwide and a higher prevalence of diabetes has been linked to those experiencing socioeconomic deprivation. Self‐management strategies are vital and known to reduce the risks of long‐... Read More about Barriers and facilitators of self‐management of diabetes amongst people experiencing socioeconomic deprivation: A systematic review and qualitative synthesis.

Serum Albumin and Post-Stroke Outcomes: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis (2024)
Journal Article
Thuemmler, R. J., Pana, T. A., Carter, B., Mahmood, R., Bettencourt-Silva, J. H., Metcalf, A. K., …Myint, P. K. (in press). Serum Albumin and Post-Stroke Outcomes: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis. Nutrients, 16(10), Article 1486. https://doi.org/10.3390/nu16101486

Hypoalbuminemia associates with poor acute ischemic stroke (AIS) outcomes. We hypothesised a non-linear relationship and aimed to systematically assess this association using prospective stroke data from the Norfolk and Norwich Stroke and TIA Registe... Read More about Serum Albumin and Post-Stroke Outcomes: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis.

Investigating Internalization of Reporter-Protein-Functionalized Polyhedrin Particles by Brain Immune Cells (2024)
Journal Article
Parwana, K. A. K., Kaur Gill, P., Njanike, R., Yiu, H. H. P., Adams, C. F., Chari, D. M., & Jenkins, S. I. (in press). Investigating Internalization of Reporter-Protein-Functionalized Polyhedrin Particles by Brain Immune Cells. Materials, 17(10), Article 2330. https://doi.org/10.3390/ma17102330

Achieving sustained drug delivery to the central nervous system (CNS) is a major challenge for neurological injury and disease, and various delivery vehicles are being developed to achieve this. Self-assembling polyhedrin crystals (POlyhedrin Deliver... Read More about Investigating Internalization of Reporter-Protein-Functionalized Polyhedrin Particles by Brain Immune Cells.

Developing an international consensus Reporting guideline for intervention Fidelity in Non-Drug, non-surgical trials: The ReFiND protocol. (2024)
Journal Article
Sousa Filho, L. F., Farlie, M. K., Haines, T., Borrelli, B., Carroll, C., Mathews, C., …Malliaras, P. (2024). Developing an international consensus Reporting guideline for intervention Fidelity in Non-Drug, non-surgical trials: The ReFiND protocol. Contemporary Clinical Trials, 142, Article 107575. https://doi.org/10.1016/j.cct.2024.107575

Inadequate reporting of fidelity to interventions in trials limits the transparency and interpretation of trial findings. Despite this, most trials of non-drug, non-surgical interventions lack comprehensive reporting of fidelity. If fidelity is poorl... Read More about Developing an international consensus Reporting guideline for intervention Fidelity in Non-Drug, non-surgical trials: The ReFiND protocol..

Reflecting on activities which support public involvement within an evaluation of public involvement reports from facilities funded by the national institute for health and care research: a co-produced commentary (2024)
Journal Article
Moult, A., Aries, A., Bailey, P., & Paskins, Z. (2024). Reflecting on activities which support public involvement within an evaluation of public involvement reports from facilities funded by the national institute for health and care research: a co-produced commentary. Research Involvement and Engagement, 10(1), 46. https://doi.org/10.1186/s40900-024-00579-x

Although including public contributors as members of research teams is becoming common, there are few reflections on how they have been incorporated, and almost none of these reflections are co-produced with public contributors. This commentary, writ... Read More about Reflecting on activities which support public involvement within an evaluation of public involvement reports from facilities funded by the national institute for health and care research: a co-produced commentary.

The Physical Demands of Wheelchair Tennis Match Play: A Systematic Review with Meta-analysis. (2024)
Journal Article
Williamson, S., Ardern, C. L., Berry, C., Heron, N., van Rensburg, D. C. J., Jansen, M. G. T., …Pluim, B. M. (in press). The Physical Demands of Wheelchair Tennis Match Play: A Systematic Review with Meta-analysis. Sports Medicine, https://doi.org/10.1007/s40279-024-02028-x

Wheelchair tennis, a globally popular sport, features a professional tour spanning 40 countries and over 160 tournaments. Despite its widespread appeal, information about the physical demands of wheelchair tennis is scattered across various studies,... Read More about The Physical Demands of Wheelchair Tennis Match Play: A Systematic Review with Meta-analysis..

The CO-produced Psychosocial INtervention delivered by GPs to young people after self-harm (COPING): protocol for a feasibility study (2024)
Journal Article
Mughal, F., Chew-Graham, C. A., Saunders, B., Lawton, S. A., Lewis, S., Smith, J., …Lewis, M. (in press). The CO-produced Psychosocial INtervention delivered by GPs to young people after self-harm (COPING): protocol for a feasibility study. NIHR Open Research, 4(27), https://doi.org/10.3310/nihropenres.13576.1

Background Self-harm in young people is a growing concern and reducing rates a global priority. General practitioners (GPs) can intervene early after self-harm but there are no effective treatments presently available. We developed the GP-led COPING... Read More about The CO-produced Psychosocial INtervention delivered by GPs to young people after self-harm (COPING): protocol for a feasibility study.

Calibration plots for multistate risk predictions models (2024)
Journal Article
Pate, A., Sperrin, M., Riley, R. D., Peek, N., Van Staa, T., Sergeant, J. C., …Martin, G. P. (in press). Calibration plots for multistate risk predictions models. Statistics in Medicine, https://doi.org/10.1002/sim.10094

Introduction There is currently no guidance on how to assess the calibration of multistate models used for risk prediction. We introduce several techniques that can be used to produce calibration plots for the transition probabilities of a multistat... Read More about Calibration plots for multistate risk predictions models.

Rural-Urban Stroke Mortality Gaps in the United States. (2024)
Journal Article
Chang, D., Ibrahim, R., Pham, H. N., Sainbayar, E., Shahid, M., Makkieh, M., …Lee, K. (in press). Rural-Urban Stroke Mortality Gaps in the United States. Journal of Stroke and Cerebrovascular Diseases, 33(8), Article 107762. https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107762

Disparities in stroke outcomes, influenced by the use of systemic thrombolysis, endovascular therapies, and rehabilitation services, have been identified. Our study assesses these disparities in mortality after stroke between rural and urban areas ac... Read More about Rural-Urban Stroke Mortality Gaps in the United States..

NIHR Race Equality Framework: development of a tool for addressing racial equality in public involvement (2024)
Journal Article
Faluyi, D., Ovseiko, P. V., Dziedzic, K., & Scott, F. (in press). NIHR Race Equality Framework: development of a tool for addressing racial equality in public involvement. Research Involvement and Engagement, 10(1), 44. https://doi.org/10.1186/s40900-024-00569-z

Background: While there has been a long recognition of the importance of race equality in health and care research, there is a lack of sustained action among research funding and research performing organisations to address racial equality in public... Read More about NIHR Race Equality Framework: development of a tool for addressing racial equality in public involvement.

ADHERENCE TO PRESCRIBED EXERCISE AND CLINICAL OUTCOMES IN PEOPLE WITH CHRONIC NONSPECIFIC LOW BACK PAIN: A SYSTEMATIC REVIEW AND META-ANALYSIS (2024)
Journal Article
Bastianon, A., Wood, L., Gilanyi, Y., Hansford, H., Gibbs, M. T., Dean, S., …Jones, M. D. (2024). ADHERENCE TO PRESCRIBED EXERCISE AND CLINICAL OUTCOMES IN PEOPLE WITH CHRONIC NONSPECIFIC LOW BACK PAIN: A SYSTEMATIC REVIEW AND META-ANALYSIS. Journal of Clinical Exercise Physiology, 13(s2), 360-360. https://doi.org/10.31189/2165-7629-13-s2.360

BACKGROUND Exercise is widely accepted as a first-line treatment for chronic non-specific low back pain (CNSLBP). However, the benefits of exercise diminish over time, as does adherence to exercise. It is unclear whether greater exercise adherence is... Read More about ADHERENCE TO PRESCRIBED EXERCISE AND CLINICAL OUTCOMES IN PEOPLE WITH CHRONIC NONSPECIFIC LOW BACK PAIN: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Understanding delays in chronic limb‐threatening ischaemia care: Application of the theoretical domains framework to identify factors affecting primary care clinicians' referral behaviours (2024)
Journal Article
Atkins, E., Birmpili, P., Kellar, I., Johal, A. S., Li, Q., Waton, S., …Cromwell, D. A. (2024). Understanding delays in chronic limb‐threatening ischaemia care: Application of the theoretical domains framework to identify factors affecting primary care clinicians' referral behaviours. Journal of Foot and Ankle Research, 17(2), Article e12015. https://doi.org/10.1002/jfa2.12015

Introduction: Patients in the community with suspected Chronic limb‐threatening ischaemia (CLTI) should be urgently referred to vascular services for investigation and management. The Theoretical Domains Framework (TDF) allows identification of influ... Read More about Understanding delays in chronic limb‐threatening ischaemia care: Application of the theoretical domains framework to identify factors affecting primary care clinicians' referral behaviours.

Impact of Society Guidelines on Trends in Use of Newer P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention (2024)
Journal Article
Mohamed, M. O., Kontopantelis, E., Alasnag, M., Abid, L., Banerjee, A., Sharp, A. S. P., …Mamas, M. A. (2024). Impact of Society Guidelines on Trends in Use of Newer P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention. Journal of the American Heart Association, 13(9), Article e034414. https://doi.org/10.1161/JAHA.124.034414

Over the past decade, major society guidelines have recommended the use of newer P2Y inhibitors over clopidogrel for those undergoing percutaneous coronary intervention for acute coronary syndrome. It is unclear what impact these recommendations had... Read More about Impact of Society Guidelines on Trends in Use of Newer P2Y12 Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention.

E-40 | Transcatheter Aortic Valve Replacement versus Surgical Aortic Valve Replacement in Patients with Bicuspid Aortic Stenosis: A Propensity Score Matching Analysis (2024)
Presentation / Conference
Rivera, F. B., Cha, S. W., Shiza, S., Redula, S., Liston, M., Carado, G., …Mamas, M. A. (2024, May). E-40 | Transcatheter Aortic Valve Replacement versus Surgical Aortic Valve Replacement in Patients with Bicuspid Aortic Stenosis: A Propensity Score Matching Analysis. Poster presented at Society for Cardiovascular Angiography & Interventions 47th Annual Scientific Sessions, Long Beach, California

Feasibility of blinding spinal manual therapy interventions among participants and outcome assessors: protocol for a blinding feasibility trial (2024)
Journal Article
Muñoz Laguna, J., Kurmann, A., Hofstetter, L., Nyantakyi, E., Clack, L., Bang, H., …Hincapié, C. A. (in press). Feasibility of blinding spinal manual therapy interventions among participants and outcome assessors: protocol for a blinding feasibility trial. Pilot and Feasibility Studies, 10(1), Article 70. https://doi.org/10.1186/s40814-024-01492-6

Introduction Blinding is a methodologically important aspect in randomised controlled trials yet frequently overlooked in trials of spinal manual therapy interventions for back pain. To help inform the blinding methods of a future, double-placebo-co... Read More about Feasibility of blinding spinal manual therapy interventions among participants and outcome assessors: protocol for a blinding feasibility trial.

Pre-school-based behaviour change intervention to increase physical activity levels amongst young children: a feasibility cluster randomised controlled trial (2024)
Journal Article
Al-walah, M. A., Donnelly, M., Alhusaini, A. A., & Heron, N. (in press). Pre-school-based behaviour change intervention to increase physical activity levels amongst young children: a feasibility cluster randomised controlled trial. Frontiers in Public Health, 12, Article 1379582. https://doi.org/10.3389/fpubh.2024.1379582

Background: A significant rise in childhood obesity worldwide over the past three decades highlights the urgent need for early interventions, especially in preschools as key settings for child development. This study aimed to assess the feasibility a... Read More about Pre-school-based behaviour change intervention to increase physical activity levels amongst young children: a feasibility cluster randomised controlled trial.

Prognostic Factors and Treatment Effect Modifiers for Physical Health, Opioid Prescription, and Health Care Utilization in Patients With Musculoskeletal Disorders in Primary Care: Exploratory Secondary Analysis of the STEMS Randomized Trial of Direct Access to Physical Therapist-Led Care. (2024)
Journal Article
Zouch, J., Bhimani, N., Bussières, A., Ferreira, M., Foster, N. E., & Ferreira, P. (in press). Prognostic Factors and Treatment Effect Modifiers for Physical Health, Opioid Prescription, and Health Care Utilization in Patients With Musculoskeletal Disorders in Primary Care: Exploratory Secondary Analysis of the STEMS Randomized Trial of Direct Access to Physical Therapist-Led Care. Physical Therapy, pzae066. https://doi.org/10.1093/ptj/pzae066

The aims of the study were to identify prognostic factors associated with health care outcomes in patients with musculoskeletal conditions in primary care and to determine whether characteristics associated with choice of care modify treatment effect... Read More about Prognostic Factors and Treatment Effect Modifiers for Physical Health, Opioid Prescription, and Health Care Utilization in Patients With Musculoskeletal Disorders in Primary Care: Exploratory Secondary Analysis of the STEMS Randomized Trial of Direct Access to Physical Therapist-Led Care..

Risk of renal disease progression in young adults with type-2-diabetes (2024)
Presentation / Conference
Perera, K., Baker, J., Jayanatha, K., Pickering, K., Cutfield, R., Orr-Walker, B. J., …Simmons, D. (2024, May). Risk of renal disease progression in young adults with type-2-diabetes. Paper presented at New Zealand Society for the Study of Diabetes (NZSSD) Annual Scientific Meeting & Annual General Meeting, Te Pae Convention Centre, 188 Oxford Tce, Ōtautahi Christchurch